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Biology and Biochemistry

D-Index
52
Citations
19790
World Ranking
16435
National Ranking
1299

Overview

Sonia Rocha is affiliated with the University of Liverpool in the United Kingdom. Their research primarily focuses on biochemical, genetic, and molecular biology areas, with a notable emphasis on molecular biology, cancer research, genetics, immunology, and epidemiology as subfields.

Rocha's recent publications illustrate their engagement with cancer biology and cellular response mechanisms, particularly under hypoxic conditions. Notable papers include:

  • Oxygen-sensing mechanisms in cells, 2020, published in FEBS Journal
  • Role of Hypoxia in the Control of the Cell Cycle, 2021, International Journal of Molecular Sciences
  • Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α, 2021, Science Signaling
  • Gene transcription and chromatin regulation in hypoxia, 2020, Biochemical Society Transactions
  • Von Hippel-Lindau (VHL) small-molecule inhibitor binding increases stability and intracellular levels of VHL protein, 2021, Journal of Biological Chemistry

The main research topics covered by Rocha include:

  • Cancer, Hypoxia, and Metabolism
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Cancer-related molecular mechanisms research
  • Interferon and immune responses
  • Mitochondrial Function and Pathology
  • Autophagy in Disease and Therapy

Frequent co-authors collaborating with Rocha include:

  • Michael Batie
  • Dilem Shakir
  • Julianty Frost
  • Niall S. Kenneth
  • Mark Frost

The scientist has published regularly in several venues, with the following appearing most frequently:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Preprints.org
  • International Journal of Molecular Sciences
  • Journal of Biological Chemistry

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of hypoxia-inducible factor-1α by NF-κB

    Patrick van Uden;Niall S. Kenneth;Sonia Rocha

  • Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB

    Kirsteen J Campbell;Sonia Rocha;Neil D Perkins

  • NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration.

    Claudio Mauro;Shi Chi Leow;Elena Anso;Sonia Rocha

  • Regulation of gene expression by hypoxia.

    Niall Steven Kenneth;Sonia Rocha

  • Ceramide Induces Cytochrome c Release from Isolated Mitochondria IMPORTANCE OF MITOCHONDRIAL REDOX STATE

    Pedram Ghafourifar;Sabine D. Klein;Olivier Schucht;Ursula Schenk

  • p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Association of the p52 NF-κB Subunit with Histone Deacetylase 1

    Sonia Rocha;Anthea M. Martin;David W. Meek;Neil D. Perkins

  • NF‐κB and HIF crosstalk in immune responses

    Laura D'Ignazio;Daniel Bandarra;Sonia Rocha

  • Hypoxia induces rapid changes to histone methylation and reprograms chromatin

    Michael Batie;Michael Batie;Julianty Frost;Mark Frost;James W. Wilson

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Gene regulation under low oxygen: holding your breath for transcription

    Sonia Rocha

  • p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

    Sonia Rocha;Kirsteen J. Campbell;Neil D. Perkins

  • Mechanism of Hypoxia-Induced NF-κB

    Carolyn Culver;Anders Sundqvist;Sharon Mudie;Andrew Melvin

  • Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

    Chiara Maniaci;Scott J. Hughes;Andrea Testa;Wenzhang Chen

  • Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

    Julianty Frost;Carles Galdeano;Carles Galdeano;Pedro Soares;Morgan S. Gadd

  • Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

    Sonia Rocha;Michelle D Garrett;Kirsteen J Campbell;Katie Schumm

  • Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB

    Laura D’Ignazio;Michael Batie;Sonia Rocha

  • The role of hypoxia in inflammatory disease (Review)

    John Biddlestone;Daniel Bandarra;Sonia Rocha

  • Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities

    Ana Teresa Pinto;Marta Laranjeiro Pinto;Ana Patrícia Cardoso;Cátia Monteiro

Frequent Co-Authors

Neil D. Perkins
Neil D. Perkins Newcastle University
Angus I. Lamond
Angus I. Lamond University of Dundee
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Raquel Seruca
Raquel Seruca University of Porto
Alessio Ciulli
Alessio Ciulli University of Dundee
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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