His primary areas of study are Immunology, Asthma, IL-2 receptor, T cell and Allergy. Many of his studies on Immunology involve topics that are commonly interrelated, such as Interleukin 12. The various areas that Dale T. Umetsu examines in his Asthma study include Lung and Etiology.
In his study, which falls under the umbrella issue of IL-2 receptor, Antigen-presenting cell is strongly linked to Interleukin 21. Within one scientific family, Dale T. Umetsu focuses on topics pertaining to Molecular biology under T cell, and may sometimes address concerns connected to Peripheral tolerance. His Allergy research incorporates themes from Inflammation, Ovalbumin, Immune tolerance and Immunotherapy.
Dale T. Umetsu spends much of his time researching Immunology, T cell, Asthma, Natural killer T cell and Allergy. Immune system, Antigen, Immunoglobulin E, Inflammation and Antigen-presenting cell are subfields of Immunology in which his conducts study. Dale T. Umetsu interconnects Cytokine, Molecular biology, Cell biology, Cytotoxic T cell and Antibody in the investigation of issues within T cell.
He has researched Asthma in several fields, including Innate immune system, Disease, Respiratory system and Lung. His research integrates issues of Acquired immune system, Airway hyperreactivity and T-cell receptor in his study of Natural killer T cell. His Allergy research integrates issues from Pathogenesis and Immunopathology.
His scientific interests lie mostly in Immunology, Asthma, Desensitization, Food allergy and Natural killer T cell. His Lung research extends to Immunology, which is thematically connected. The study incorporates disciplines such as Odds ratio, Randomized controlled trial and Pediatrics in addition to Asthma.
The concepts of his Desensitization study are interwoven with issues in Omalizumab and Immunoglobulin E. His studies deal with areas such as Allergen and Immunotherapy as well as Food allergy. He has included themes like Hygiene hypothesis, Dendritic cell, Microbiology, Interleukin 33 and Allergic sensitization in his Natural killer T cell study.
Dale T. Umetsu mainly investigates Immunology, Desensitization, Immunoglobulin E, Omalizumab and Food allergy. His work in Innate lymphoid cell, Allergic inflammation, Antigen and Mucosal immunology is related to Immunology. His Innate lymphoid cell research is multidisciplinary, relying on both Natural killer T cell and Interleukin 33.
His work deals with themes such as Inflammation and Autoimmunity, Immune system, which intersect with Antigen. In Inflammation, Dale T. Umetsu works on issues like Immunity, which are connected to Cellular differentiation and T cell. His Food allergy study combines topics from a wide range of disciplines, such as Allergen, Immune tolerance, Internal medicine, Cumulative dose and Immunotherapy.
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Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen.
Omid Akbari;Rosemarie H. DeKruyff;Dale T. Umetsu.
Nature Immunology (2001)
Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
Omid Akbari;Gordon J. Freeman;Everett H. Meyer;Edward A. Greenfield.
Nature Medicine (2002)
Extrathymically generated regulatory T cells control mucosal T H 2 inflammation
Steven Z. Josefowicz;Rachel E. Niec;Hye Young Kim;Piper Treuting.
Nature (2012)
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
Omid Akbari;Philippe Stock;Everett Meyer;Mitchell Kronenberg.
Nature Medicine (2003)
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
Ya Jen Chang;Hye Young Kim;Lee A. Albacker;Nicole Baumgarth.
Nature Immunology (2011)
Asthma: an epidemic of dysregulated immunity.
Dale T. Umetsu;Jennifer J. McIntire;Omid Akbari;Claudia Macaubas.
Nature Immunology (2002)
Allergen-specific Th1 cells fail to counterbalance Th2 cell–induced airway hyperreactivity but cause severe airway inflammation
Gesine Hansen;Gerald Berry;Rosemarie H. DeKruyff;Dale T. Umetsu.
Journal of Clinical Investigation (1999)
The many paths to asthma: phenotype shaped by innate and adaptive immunity
Hye Young Kim;Rosemarie H DeKruyff;Dale T Umetsu.
Nature Immunology (2010)
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
Jennifer J. McIntire;Sarah E. Umetsu;Omid Akbari;Michael Potter.
Nature Immunology (2001)
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
Norimoto Kobayashi;Piia Karisola;Victor Peña-Cruz;David M. Dorfman.
Immunity (2007)
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