D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 62 Citations 15,652 137 World Ranking 2141 National Ranking 79

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Cytokine
  • Antibody

Hisaya Akiba focuses on Immunology, Cell biology, T cell, Tumor necrosis factor alpha and Molecular biology. Interleukin 21, Interferon gamma, Antibody, Antigen and Monoclonal antibody are the core of his Immunology study. His Interleukin 21 research focuses on Perforin and how it relates to Lymphokine-activated killer cell, Interleukin 12, NK-92 and Natural killer cell.

He has researched Cell biology in several fields, including CD40, Protein kinase R, Cyclin-dependent kinase 2, CD28 and Peripheral tolerance. His T cell study integrates concerns from other disciplines, such as Immune tolerance and B cell. His Molecular biology research incorporates elements of Cell culture, Stromal cell, Fas ligand and Cytotoxic T cell, Antigen-presenting cell.

His most cited work include:

  • Expression of Programmed Death 1 Ligands by Murine T Cells and APC (761 citations)
  • The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice (623 citations)
  • Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis (416 citations)

What are the main themes of his work throughout his whole career to date?

Hisaya Akiba mostly deals with Immunology, T cell, Cell biology, Antibody and Molecular biology. As part of one scientific family, he deals mainly with the area of Immunology, narrowing it down to issues related to the Blockade, and often Transplantation. His T cell study incorporates themes from Cytotoxic T cell and CD8.

His work carried out in the field of Cell biology brings together such families of science as CD28, Receptor, Cytokine and CD40. His Tumor necrosis factor alpha research is multidisciplinary, incorporating elements of Interferon, Cancer research and Interferon gamma. Hisaya Akiba interconnects Perforin and Interleukin 12 in the investigation of issues within Interleukin 21.

He most often published in these fields:

  • Immunology (63.33%)
  • T cell (32.67%)
  • Cell biology (24.00%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (63.33%)
  • T cell (32.67%)
  • Antibody (18.67%)

In recent papers he was focusing on the following fields of study:

Hisaya Akiba mainly investigates Immunology, T cell, Antibody, Cell biology and Immune system. His Immunology study combines topics from a wide range of disciplines, such as Cytotoxic T cell and Blockade. His T cell study combines topics in areas such as Immune checkpoint, Immunotherapy, Cancer research, Melanoma and Monoclonal antibody.

His study looks at the relationship between Cancer research and fields such as Transforming growth factor, as well as how they intersect with chemical problems. His studies examine the connections between Antibody and genetics, as well as such issues in Cornea, with regards to Transmembrane protein, Immunohistochemistry and CD11c. His Cell biology research incorporates themes from Programmed death 1, Interleukin 21, Receptor, Mucin and Arterial blood.

Between 2012 and 2021, his most popular works were:

  • TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance. (64 citations)
  • TIM-3 Regulates Innate Immune Cells To Induce Fetomaternal Tolerance (61 citations)
  • Monocyte-Derived Dendritic Cells Perform Hemophagocytosis to Fine-Tune Excessive Immune Responses (57 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Cytokine
  • Antibody

His primary areas of investigation include Immunology, Immune system, Cytotoxic T cell, Inflammation and Antibody. His research integrates issues of Apoptosis and Receptor in his study of Immunology. Hisaya Akiba is involved in the study of Immune system that focuses on T cell in particular.

His research in Inflammation intersects with topics in Eosinophil, Cytokine, Proteases, Cysteine protease and Innate lymphoid cell. The various areas that he examines in his Antibody study include Corneal epithelium and IL-2 receptor. As part of the same scientific family, Hisaya Akiba usually focuses on In vivo, concentrating on Adoptive cell transfer and intersecting with Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Expression of Programmed Death 1 Ligands by Murine T Cells and APC

Tomohide Yamazaki;Hisaya Akiba;Hideyuki Iwai;Hironori Matsuda.
Journal of Immunology (2002)

1247 Citations

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.

Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith.
Journal of Experimental Medicine (2003)

886 Citations

Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama.
Nature Immunology (2012)

652 Citations

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;Jaime Imitola;Jaime Imitola;Mohammed Javeed I. Ansari.
Journal of Experimental Medicine (2003)

627 Citations

Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors

Shin Foong Ngiow;Bianca von Scheidt;Hisaya Akiba;Hideo Yagita.
Cancer Research (2011)

557 Citations

Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda.
Journal of Immunology (1999)

461 Citations

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

Qing Ding;Melissa Yeung;Geoffrey Camirand;Qiang Zeng.
Journal of Clinical Investigation (2011)

459 Citations

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.

Masafumi Nakayama;Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima.
Blood (2009)

456 Citations

The Role of ICOS in the CXCR5+ Follicular B Helper T Cell Maintenance In Vivo

Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima;Yoshihiko Usui.
Journal of Immunology (2005)

433 Citations

Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

Toshiro Futagawa;Hisaya Akiba;Tomohiro Kodama;Kazuyoshi Takeda.
International Immunology (2002)

405 Citations

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