World's Best Scientists 2026 revealed!
Hisaya Akiba

Hisaya Akiba

D-Index & Metrics

Immunology

D-Index
67
Citations
17670
World Ranking
2658
National Ranking
104

Overview

Hisaya Akiba is affiliated with Juntendo University in Japan, contributing to various research areas primarily within medicine, biochemistry, genetics, and molecular biology. Their work extensively covers immunology and microbiology, with subfields including immunology, molecular biology, physiology, oncology, and immunology and allergy.

The scientist's research topics focus on asthma and respiratory diseases, galectins and cancer biology, IL-33, ST2, and ILC pathways, inflammasome and immune disorders, immune cell function and interaction, phagocytosis and immune regulation, and allergic rhinitis and sensitization.

Akiba has authored multiple papers in notable journals, including:

  • Gasdermin D-mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma, 2022, Science Immunology
  • Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation, 2021, Cell Reports
  • ImmunoPET Imaging of TIM-3 in Murine Melanoma Models, 2020, Advanced Therapeutics
  • Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmatics, 2023, Allergology International
  • Pretreatment Frequency of Circulating Th17 Cells and FeNO Levels Predicted the Real-World Response after 1 Year of Benralizumab Treatment in Patients with Severe Asthma, 2023, Biomolecules

Frequent publication venues where Akiba has contributed include Respirology, Allergology International, Biomolecules, Science Immunology, and Cell Reports.

Collaboration is a significant aspect of Akiba's research activity, with frequent co-authors including Norihiro Harada, Kazuhisa Takahashi, Sonoko Harada, Hitoshi Sasano, and Yuuki Sandhu, each contributing to multiple joint publications.

Best Publications

  • Expression of Programmed Death 1 Ligands by Murine T Cells and APC

    Tomohide Yamazaki;Hisaya Akiba;Hideyuki Iwai;Hironori Matsuda

  • The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.

    Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith

  • Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

    Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama

  • Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

    Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;Jaime Imitola;Jaime Imitola;Mohammed Javeed I. Ansari

  • Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors

    Shin Foong Ngiow;Bianca von Scheidt;Hisaya Akiba;Hideo Yagita

  • Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.

    Masafumi Nakayama;Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima

  • Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

    Qing Ding;Melissa Yeung;Geoffrey Camirand;Qiang Zeng

  • Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda

  • The Role of ICOS in the CXCR5+ Follicular B Helper T Cell Maintenance In Vivo

    Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima;Yoshihiko Usui

  • Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

    Toshiro Futagawa;Hisaya Akiba;Tomohiro Kodama;Kazuyoshi Takeda

  • Eradication of established tumors in mice by a combination antibody-based therapy.

    Tomoyasu Uno;Kazuyoshi Takeda;Kazuyoshi Takeda;Yuko Kojima;Hirohisa Yoshizawa

  • Critical Contribution of Ox40 Ligand to T Helper Cell Type 2 Differentiation in Experimental Leishmaniasis

    Hisaya Akiba;Yasushi Miyahira;Machiko Atsuta;Kazuyoshi Takeda

  • CD27, a Member of the Tumor Necrosis Factor Receptor Superfamily, Activates NF-κB and Stress-activated Protein Kinase/c-Jun N-terminal Kinase via TRAF2, TRAF5, and NF-κB-inducing Kinase *

    Hisaya Akiba;Hiroyasu Nakano;Shigeyuki Nishinaka;Masahisa Shindo

  • Involvement of TNF-Related Apoptosis-Inducing Ligand in Human CD4+ T Cell-Mediated Cytotoxicity

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Akemi Kawasaki

  • TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.

    Kazuyoshi Takeda;Erika Cretney;Erika Cretney;Erika Cretney;Yoshihiro Hayakawa;Yoshihiro Hayakawa;Yoshihiro Hayakawa;Tsuyoshi Ota;Tsuyoshi Ota;Tsuyoshi Ota

  • RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

    Kathryn A. Knoop;Nachiket Kumar;Betsy R. Butler;Senthilkumar K. Sakthivel

  • Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy

    Kazuyoshi Takeda;Noriko Yamaguchi;Hisaya Akiba;Yuko Kojima

  • OX40 (CD134) Controls Memory T Helper 2 Cells that Drive Lung Inflammation

    Shahram Salek-Ardakani;Jianxun Song;Beth S. Halteman;Amha Gebre-Hiwot Jember

  • Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

    Takanori Kanai;Teruji Totsuka;Koji Uraushihara;Shin Makita

  • CD28-Independent Costimulation of T Cells by OX40 Ligand and CD70 on Activated B Cells

    Hisaya Akiba;Hideo Oshima;Kazuyoshi Takeda;Machiko Atsuta

Frequent Co-Authors

Hideo Yagita
Hideo Yagita Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Miyuki Azuma
Miyuki Azuma Tokyo Medical and Dental University
Kazuyoshi Takeda
Kazuyoshi Takeda Juntendo University
Nader Najafian
Nader Najafian Brigham and Women's Hospital
Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Alan D. Salama
Alan D. Salama University College London
Tetsuji Kobata
Tetsuji Kobata Tokyo Medical and Dental University
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Samia J. Khoury
Samia J. Khoury American University of Beirut

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Immunology, exploring related healthcare fields like nursing can open diverse career opportunities. Many professionals pursue advanced nursing degrees to enhance their expertise in patient care and biomedical sciences.

One popular route is through cheapest online pmhnp programs, which offer affordable paths to becoming a Psychiatric-Mental Health Nurse Practitioner with flexible learning options. These programs provide a strong foundation in mental health and immunological function.

For those aiming for higher earnings, examining the highest paid dnp specialties reveals that specialties focusing on acute and advanced care often command impressive salaries. This is valuable when considering long-term career goals.

Transitioning within nursing roles is also feasible, as outlined in guides about acute care nurse practitioner programs. Such programs help Nurse Practitioners shift their focus toward acute care settings, a realm closely linked to immunological responses.

Additionally, accelerated options like the accelerated fnp program enable registered nurses to quickly advance their education and credentials, expediting entry into advanced practice roles.

Exploring these online degrees can complement an Immunology background, fostering interdisciplinary skills essential in healthcare innovation and patient treatment.

Best Scientists Citing Hisaya Akiba

Trending Scientists

Recently Published Articles