Hisaya Akiba focuses on Immunology, Cell biology, T cell, Tumor necrosis factor alpha and Molecular biology. Interleukin 21, Interferon gamma, Antibody, Antigen and Monoclonal antibody are the core of his Immunology study. His Interleukin 21 research focuses on Perforin and how it relates to Lymphokine-activated killer cell, Interleukin 12, NK-92 and Natural killer cell.
He has researched Cell biology in several fields, including CD40, Protein kinase R, Cyclin-dependent kinase 2, CD28 and Peripheral tolerance. His T cell study integrates concerns from other disciplines, such as Immune tolerance and B cell. His Molecular biology research incorporates elements of Cell culture, Stromal cell, Fas ligand and Cytotoxic T cell, Antigen-presenting cell.
Hisaya Akiba mostly deals with Immunology, T cell, Cell biology, Antibody and Molecular biology. As part of one scientific family, he deals mainly with the area of Immunology, narrowing it down to issues related to the Blockade, and often Transplantation. His T cell study incorporates themes from Cytotoxic T cell and CD8.
His work carried out in the field of Cell biology brings together such families of science as CD28, Receptor, Cytokine and CD40. His Tumor necrosis factor alpha research is multidisciplinary, incorporating elements of Interferon, Cancer research and Interferon gamma. Hisaya Akiba interconnects Perforin and Interleukin 12 in the investigation of issues within Interleukin 21.
Hisaya Akiba mainly investigates Immunology, T cell, Antibody, Cell biology and Immune system. His Immunology study combines topics from a wide range of disciplines, such as Cytotoxic T cell and Blockade. His T cell study combines topics in areas such as Immune checkpoint, Immunotherapy, Cancer research, Melanoma and Monoclonal antibody.
His study looks at the relationship between Cancer research and fields such as Transforming growth factor, as well as how they intersect with chemical problems. His studies examine the connections between Antibody and genetics, as well as such issues in Cornea, with regards to Transmembrane protein, Immunohistochemistry and CD11c. His Cell biology research incorporates themes from Programmed death 1, Interleukin 21, Receptor, Mucin and Arterial blood.
His primary areas of investigation include Immunology, Immune system, Cytotoxic T cell, Inflammation and Antibody. His research integrates issues of Apoptosis and Receptor in his study of Immunology. Hisaya Akiba is involved in the study of Immune system that focuses on T cell in particular.
His research in Inflammation intersects with topics in Eosinophil, Cytokine, Proteases, Cysteine protease and Innate lymphoid cell. The various areas that he examines in his Antibody study include Corneal epithelium and IL-2 receptor. As part of the same scientific family, Hisaya Akiba usually focuses on In vivo, concentrating on Adoptive cell transfer and intersecting with Cell biology.
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Expression of Programmed Death 1 Ligands by Murine T Cells and APC
Tomohide Yamazaki;Hisaya Akiba;Hideyuki Iwai;Hironori Matsuda.
Journal of Immunology (2002)
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.
Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith.
Journal of Experimental Medicine (2003)
Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama.
Nature Immunology (2012)
Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis
Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;Jaime Imitola;Jaime Imitola;Mohammed Javeed I. Ansari.
Journal of Experimental Medicine (2003)
Anti-TIM3 Antibody Promotes T Cell IFN-γ–Mediated Antitumor Immunity and Suppresses Established Tumors
Shin Foong Ngiow;Bianca von Scheidt;Hisaya Akiba;Hideo Yagita.
Cancer Research (2011)
Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.
Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Kazuyoshi Takeda.
Journal of Immunology (1999)
Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
Qing Ding;Melissa Yeung;Geoffrey Camirand;Qiang Zeng.
Journal of Clinical Investigation (2011)
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.
Masafumi Nakayama;Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima.
The Role of ICOS in the CXCR5+ Follicular B Helper T Cell Maintenance In Vivo
Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima;Yoshihiko Usui.
Journal of Immunology (2005)
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells
Toshiro Futagawa;Hisaya Akiba;Tomohiro Kodama;Kazuyoshi Takeda.
International Immunology (2002)
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