World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
92
Citations
37360
World Ranking
997
National Ranking
32

Medicine

D-Index
92
Citations
37543
World Ranking
11162
National Ranking
321

Overview

Miyuki Azuma is affiliated with Tokyo Medical and Dental University in Japan. Their research primarily focuses on immunology and microbiology, with significant contributions to medicine. The subfields of study include immunology, oncology, genetics, pulmonary and respiratory medicine, and surgery.

The scientist's work extensively covers topics related to cancer immunotherapy and biomarkers, immunotherapy and immune responses, and immune cell function and interaction. Other prominent topics in their research include immune cells in cancer, CAR-T cell therapy research, immune response and inflammation, and T-cell and B-cell immunology.

Miyuki Azuma has collaborated frequently with colleagues including Shigenori Nagai, Naoto Nishii, Yohei Kawano, Pissacha Daroonpan, and Hiroyuki Harada.

Their recent published papers include:
- Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade, 2022, Diabetologia
- PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment, 2021, Communications Biology
- High density and proximity of CD8+T cells to tumor cells are correlated with better response to nivolumab treatment in metastatic pleural mesothelioma, 2023, Thoracic Cancer
- Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model, 2020, Cancer Immunology Immunotherapy
- Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters, 2023, Nature Communications

Publication venues where Miyuki Azuma's work appears regularly include:

  • Biochemical and Biophysical Research Communications
  • Cancer Immunology Immunotherapy
  • Diabetologia
  • Communications Biology
  • Thoracic Cancer

Best Publications

  • Expression of Programmed Death 1 Ligands by Murine T Cells and APC

    Tomohide Yamazaki;Hisaya Akiba;Hideyuki Iwai;Hironori Matsuda

  • Clinical Significance and Therapeutic Potential of the Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer

    Takeo Nomi;Masayuki Sho;Takahiro Akahori;Kaoru Hamada

  • Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

    Tadashi Yokosuka;Masako Takamatsu;Wakana Kobayashi-Imanishi;Akiko Hashimoto-Tane

  • B70 antigen is a second ligand for CTLA-4 and CD28

    Miyuki Azuma;Daisuke Ito;Daisuke Ito;Hideo Yagita;Ko Okumura

  • Clinical Significance of Programmed Death-1 Ligand-1 and Programmed Death-1 Ligand-2 Expression in Human Esophageal Cancer

    Yuichiro Ohigashi;Masayuki Sho;Yukishige Yamada;Yoshikazu Tsurui

  • The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.

    Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith

  • B7-H1 Expression on Non-Small Cell Lung Cancer Cells and Its Relationship with Tumor-Infiltrating Lymphocytes and Their PD-1 Expression

    Jun Konishi;Koichi Yamazaki;Miyuki Azuma;Ichiro Kinoshita

  • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

    Madhav D. Sharma;Babak Baban;Phillip Chandler;De Yan Hou

  • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

    Brian T Fife;Kristen E Pauken;Todd N Eagar;Takashi Obu

  • The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.

    K Inaba;M Witmer-Pack;M Inaba;K S Hathcock

  • Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

    Qing Zhou;Meghan E. Munger;Rachelle G. Veenstra;Brenda J. Weigel

  • Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

    M G Cifone;R De Maria;P Roncaioli;M R Rippo

  • CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.

    L L Lanier;S O'Fallon;C Somoza;J H Phillips

  • Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

    Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;Jaime Imitola;Jaime Imitola;Mohammed Javeed I. Ansari

  • Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers.

    Juro Nakanishi;Yoshihiro Wada;Koichiro Matsumoto;Miyuki Azuma

  • Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.

    Masafumi Nakayama;Hisaya Akiba;Kazuyoshi Takeda;Yuko Kojima

  • CD28- T lymphocytes. Antigenic and functional properties.

    M Azuma;J H Phillips;L L Lanier

  • A critical role for the programmed death ligand 1 in fetomaternal tolerance.

    Indira Guleria;Arezou Khosroshahi;Mohammed Javeed I Ansari;Antje Habicht

  • CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes.

    Miyuki Azuma;Mark Cayabyab;David Buck;Joseph H. Phillips

  • B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.

    C Caux;B Vanbervliet;C Massacrier;M Azuma

Frequent Co-Authors

Hideo Yagita
Hideo Yagita Juntendo University
Ko Okumura
Ko Okumura Juntendo University
Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Hisaya Akiba
Hisaya Akiba Juntendo University
Lieping Chen
Lieping Chen Yale University
Hiromasa Inoue
Hiromasa Inoue Kagoshima University
Nader Najafian
Nader Najafian Brigham and Women's Hospital
Pascal Schneider
Pascal Schneider University of Lausanne
Tetsuji Kobata
Tetsuji Kobata Tokyo Medical and Dental University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo

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