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Immunology

D-Index
97
Citations
46250
World Ranking
805
National Ranking
72

Medicine

D-Index
97
Citations
46325
World Ranking
9119
National Ranking
889

Overview

Andrew L. Mellor is affiliated with Newcastle University in the United Kingdom. Their research primarily focuses on medicine, with significant contributions to immunology and microbiology. They have published extensively across several subfields, including immunology, oncology, molecular biology, materials chemistry, and rheumatology.

Their work covers a range of main topics that include:

  • Immune Cell Function and Interaction
  • Tryptophan and brain disorders
  • Interferon and immune responses
  • Peptidase Inhibition and Analysis
  • Cancer Immunotherapy and Biomarkers
  • Hydrogels: synthesis, properties, applications
  • T-cell and B-cell Immunology

Mellor has contributed to several scientific papers, with notable recent publications including:

  • CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint, 2020, Nature Communications
  • Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment, 2020, Cell Death and Differentiation
  • Novel delivery of cellular therapy to reduce ischemia reperfusion injury in kidney transplantation, 2020, American Journal of Transplantation
  • Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity, 2020, Journal for ImmunoTherapy of Cancer
  • Genipin-crosslinked chitosan hydrogels: Preliminary evaluation of the in vitro biocompatibility and biodegradation, 2021, Journal of Applied Polymer Science

Frequent co-authors in Mellor's work include Lei Huang, Henrique Lemos, Arthur G. Pratt, John D. Isaacs, and Amy E. Anderson.

Several publication venues have featured their work multiple times, which include:

  • Journal of Applied Polymer Science
  • Frontiers in Immunology
  • Annals of the Rheumatic Diseases
  • Nature Communications
  • Cell Death and Differentiation

Mellor has also contributed to book publications, notably with Yale University Press, with the work titled The Northern Silence published in 2022.

Best Publications

  • Prevention of allogeneic fetal rejection by tryptophan catabolism

    David H. Munn;Min Zhou;John T. Attwood;Igor Bondarev

  • IDO expression by dendritic cells: tolerance and tryptophan catabolism.

    Andrew L. Mellor;David H. Munn

  • Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

    Brian J. Miller;Peter Buckley;Wesley Seabolt;Andrew Mellor

  • INHIBITION OF T CELL PROLIFERATION BY MACROPHAGE TRYPTOPHAN CATABOLISM

    David H. Munn;Ebrahim Shafizadeh;John T. Attwood;Igor Bondarev

  • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

    David H. Munn;Madhav D. Sharma;Babak Baban;Heather P. Harding

  • Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

    David H. Munn;Madhav D. Sharma;Jeffrey R. Lee;Kanchan G. Jhaver

  • Indoleamine 2,3-dioxygenase and tumor-induced tolerance.

    David H. Munn;Andrew L. Mellor

  • Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

    David H. Munn;Madhav D. Sharma;Deyan Hou;Babak Baban

  • Indoleamine 2,3 dioxygenase and metabolic control of immune responses

    David H. Munn;Andrew L. Mellor

  • IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

    David H. Munn;Andrew L. Mellor

  • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

    Madhav D. Sharma;Babak Baban;Phillip Chandler;De Yan Hou

  • cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

    Christer Betsholtz;Ann Johnsson;Carl-Henrik Heldin;Bengt Westermark

  • Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

    Andrew L Mellor;David H Munn

  • Eosinophilia in transgenic mice expressing interleukin 5.

    Lindsay A. Dent;Malcolm Strath;Andrew L. Mellor;Colin J. Sanderson

  • Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses

    De Yan Hou;Alexander J. Muller;Madhav D. Sharma;James DuHadaway

  • Ligation of B7-1/B7-2 by Human CD4+ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells

    David H. Munn;Madhav D. Sharma;Andrew L. Mellor

  • Cutting Edge: Induced Indoleamine 2,3 Dioxygenase Expression in Dendritic Cell Subsets Suppresses T Cell Clonal Expansion

    Andrew L. Mellor;Babak Baban;Phillip Chandler;Brendan Marshall

  • IDO Activates Regulatory T Cells and Blocks Their Conversion into Th17-Like T Cells

    Babak Baban;Phillip R. Chandler;Madhav D. Sharma;Jeanene Pihkala

  • Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

    Andrew L. Mellor;Jayabalan Sivakumar;Phillip Chandler;Kimberly Smith

  • A critical role for the programmed death ligand 1 in fetomaternal tolerance.

    Indira Guleria;Arezou Khosroshahi;Mohammed Javeed I Ansari;Antje Habicht

  • Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

    Geon Kook Lee;Hyeon Jin Park;Megan Macleod;Phillip Chandler

Frequent Co-Authors

David H. Munn
David H. Munn Augusta University
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
George C. Prendergast
George C. Prendergast Lankenau Institute for Medical Research
Pandelakis A. Koni
Pandelakis A. Koni Elixiron Immunotherapeutics (Taiwan)
Alexander J. Muller
Alexander J. Muller Lankenau Institute for Medical Research
Kebin Liu
Kebin Liu Augusta University
Peter F. Buckley
Peter F. Buckley University of Tennessee Health Science Center
Richard A. Flavell
Richard A. Flavell Yale University
Hideo Yagita
Hideo Yagita Juntendo University
Elizabeth M. Simpson
Elizabeth M. Simpson University of British Columbia

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