World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
103
Citations
52773
World Ranking
7218
National Ranking
3788

Overview

Shih-Jen Hwang is affiliated with the National Institutes of Health in the United States and has a substantial record of research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work intersects several subfields including Genetics, Molecular Biology, Cardiology and Cardiovascular Medicine, Nephrology, and Physiology.

The main topics covered in the research include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Chronic Kidney Disease and Diabetes, RNA modifications and cancer, Birth, Development, and Health, Bioinformatics and Genomic Networks, and Adipokines, Inflammation, and Metabolic Diseases.

Their recent publications include:

  • Development and Validation of the American Heart Association's PREVENT Equations, 2023, Circulation
  • Genetic diversity fuels gene discovery for tobacco and alcohol use, 2022, Nature
  • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals, 2020, Nature Genetics
  • Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes, 2023, JAMA
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification, 2023, Nature Genetics

Frequent co-authors in Hwang's work include Daniel Levy, Chen Yao, Bruce M. Psaty, Joshua C. Bis, and Jerome I. Rotter.

Their research has been published multiple times in notable venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Circulation, and Nature Genetics.

Best Publications

  • Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.

    Kunihiro Matsushita;Marije van der Velde;Brad C. Astor;Mark Woodward

  • Arterial Stiffness and Cardiovascular Events The Framingham Heart Study

    Gary F. Mitchell;Shih-Jen Hwang;Ramachandran S. Vasan;Martin G. Larson

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: The Atherosclerosis Risk In Communities (ARIC) study

    Shih Jen Hwang;Christie M. Ballantyne;A. Richey Sharrett;Louis C. Smith

  • Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects

    Yoav Ben-Shlomo;Melissa Spears;Chris Boustred;Margaret May

  • Genome-wide association study of blood pressure and hypertension

    Daniel Levy;Georg B. Ehret;Georg B. Ehret;Kenneth Rice;Germaine C. Verwoert

  • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

    Gareth L. Bond;Wenwei Hu;Elisabeth E. Bond;Harlan Robins

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior

    Helena Furberg;Yunjung Kim;Jennifer Dackor;Eric Boerwinkle

  • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

    Elizabeth K. Speliotes;Laura M. Yerges-Armstrong;Jun Wu;Ruben Hernaez;Ruben Hernaez

  • Genetic associations with valvular calcification and aortic stenosis.

    George Thanassoulis;George Thanassoulis;Catherine Y. Campbell;David S. Owens;J. Gustav Smith;J. Gustav Smith

  • New loci associated with kidney function and chronic kidney disease

    Anna Köttgen;Anna Köttgen;Cristian Pattaro;Carsten A. Böger;Christian Fuchsberger

  • Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

    Abbas Dehghan;Anna Köttgen;Qiong Yang;Shih Jen Hwang

  • Trends in All-Cause and Cardiovascular Disease Mortality Among Women and Men With and Without Diabetes Mellitus in the Framingham Heart Study, 1950 to 2005

    Sarah Rosner Preis;Shih-Jen Hwang;Sean Coady;Michael J. Pencina

  • Multiple loci associated with indices of renal function and chronic kidney disease

    Anna Köttgen;Nicole L. Glazer;Abbas Dehghan;Shih Jen Hwang

  • A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Majid Nikpay;Anuj Goel;Hong-Hee Won;Leanne M. Hall

  • Adiposity, Cardiometabolic Risk, and Vitamin D Status: The Framingham Heart Study

    Susan Cheng;Joseph M. Massaro;Joseph M. Massaro;Caroline S. Fox;Caroline S. Fox;Martin G. Larson;Martin G. Larson

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Caroline S. Fox
Caroline S. Fox MSD (United States)
Daniel Levy
Daniel Levy National Institutes of Health
Christopher J. O'Donnell
Christopher J. O'Donnell Harvard Medical School
Bruce M. Psaty
Bruce M. Psaty University of Washington
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Ramachandran S. Vasan
Ramachandran S. Vasan The University of Texas Health Science Center at San Antonio
Albert Hofman
Albert Hofman Harvard University
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor
Vilmundur Gudnason
Vilmundur Gudnason University of Iceland

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