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Immunology

D-Index
82
Citations
22619
World Ranking
1514
National Ranking
129

Overview

Stephen P. Cobbold is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology, cell biology, and immunology.

Their recent academic contributions include publications on the regulation and maintenance of Lck activity in T cells, covering aspects of lipid membrane structure and behavior as well as sphingolipid metabolism and signaling. The two recent papers are:

  • Role of the membrane anchor in the regulation of Lck activity, 2022, Journal of Biological Chemistry
  • A role of Lck annular lipids in the steady upkeep of active Lck in T cells, 2022, bioRxiv (Cold Spring Harbor Laboratory)

The scientist's work addresses several main topics, including:

  • Lipid Membrane Structure and Behavior
  • Sphingolipid Metabolism and Signaling
  • Cellular transport and secretion
  • Immune Response and Inflammation

Frequent collaborators in their research projects include Nicla Porciello, Deborah Cipria, Giulia Masi, Anna-Lisa Lanz, and Edoardo Milanetti, each appearing as coauthors on multiple publications.

Their research has been disseminated mainly through two publication venues:

  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Stephen P. Cobbold's focused approach on biochemical mechanisms related to lipid membranes and immune cell functions contributes to ongoing studies in cellular transport, secretion, and inflammation processes within their fields of study.

Best Publications

  • Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

    S P Cobbold;A Jayasuriya;A Nash;T D Prospero

  • "Infectious" transplantation tolerance

    Shixin Qin;Stephen P. Cobbold;Heather Pope;James Elliott

  • Identification of regulatory T cells in tolerated allografts

    Luis Graca;Stephen P. Cobbold;Herman Waldmann

  • Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants.

    Stephen P. Cobbold;Raquel Castejon;Elizabeth Adams;Diana Zelenika

  • Both CD4+CD25+ and CD4+CD25− Regulatory Cells Mediate Dominant Transplantation Tolerance

    Luis Graca;Sara Thompson;Chun-Yen Lin;Elizabeth Adams

  • Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

    Masahide Tone;Yukiko Tone;Elizabeth Adams;Stephen F. Yates

  • Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance

    S. P. Cobbold;G. Martin;S. Qin;H. Waldmann

  • Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells.

    I Müller;S P Cobbold;H Waldmann;S H Kaufmann

  • Induction of classical transplantation tolerance in the adult.

    Shixin Qin;S. Cobbold;R. Benjamin;H. Waldmann

  • Humanised monoclonal antibody therapy for rheumatoid arthritis.

    J D Isaacs;R A Watts;B L Hazleman;G Hale

  • Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase.

    Andrew L. Mellor;Phillip Chandler;Babak Baban;Anna M. Hansen

  • Infectious tolerance via the consumption of essential amino acids and mTOR signaling

    Stephen P. Cobbold;Elizabeth Adams;Claire A. Farquhar;Kathleen F. Nolan

  • T cell suppression in transplantation tolerance through linked recognition.

    Joanna D. Davies;Louise Y W Leong;Andrew Mellor;Stephen P. Cobbold

  • Induction of tolerance in peripheral T cells with monoclonal antibodies.

    Shixin Qin;Matt Wise;Stephen P. Cobbold;Louise Leong

  • Monoclonal-antibody therapy in systemic vasculitis.

    P. W. Mathieson;S. P. Cobbold;G. Hale;M. R. Clark

  • CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression.

    Karen Honey;Stephen P. Cobbold;Herman Waldmann

  • Regulating the immune response to transplants. a role for CD4+ regulatory cells?

    Herman Waldmann;Stephen Cobbold

  • Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system.

    Anthony Nash;A Jayasuriya;J Phelan;S.P Cobbold

  • Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8.

    Stephen P. Cobbold;Elizabeth Adams;Sara E. Marshall;Joanna D. Davies

  • Autoimmune Diabetes Onset Results From Qualitative Rather Than Quantitative Age-Dependent Changes in Pathogenic T-Cells

    Sylvaine You;Mériam Belghith;Stephen Cobbold;Marie-Alexandra Alyanakian

  • Regulatory T cells in transplantation tolerance.

    H Waldmann;L Graca;E Adams;P J Fairchild

Frequent Co-Authors

Herman Waldmann
Herman Waldmann University of Oxford
Luis Graca
Luis Graca University of Lisbon
Peter J. Friend
Peter J. Friend University of Oxford
Andrew L. Mellor
Andrew L. Mellor Newcastle University
Shohei Hori
Shohei Hori University of Tokyo
John D. Isaacs
John D. Isaacs Newcastle University
David R. Greaves
David R. Greaves University of Oxford
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Amit C. Nathwani
Amit C. Nathwani University College London

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