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D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
26382
World Ranking
4483
National Ranking
339

Overview

David R. Greaves is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on medicine, immunology and microbiology, and biochemistry, genetics and molecular biology. Within these main fields, their work spans several subfields including immunology, molecular biology, oncology, biomedical engineering, and genetics.

The key topics covered in their research involve immune cells in cancer, cytokine signaling pathways and interactions, receptor mechanisms and signaling, congenital heart defects research, lymphatic system and diseases, inflammasome and immune disorders, and adipokines, inflammation, and metabolic diseases.

David R. Greaves has authored multiple recent papers, including:

  • Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair, 2020, Nature Communications
  • Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart, 2021, Development
  • Inhibition of Bruton's TK regulates macrophage NF-κB and NLRP3 inflammasome activation in metabolic inflammation, 2020, British Journal of Pharmacology
  • NF-κB Signaling and Inflammation-Drug Repurposing to Treat Inflammatory Disorders?, 2022, Biology
  • 20 Years an Orphan: Is GPR84 a Plausible Medium-Chain Fatty Acid-Sensing Receptor?, 2020, DNA and Cell Biology

Key frequent co-authors they have collaborated with include Gareth S. D. Purvis, Keith M. Channon, Vincent B. Luscombe, Angela J. Russell, and Annabell Roberti.

The primary venues where David R. Greaves has published include bioRxiv (Cold Spring Harbor Laboratory), British Journal of Pharmacology, Biology, Frontiers in Immunology, and European Journal of Pharmacology.

Best Publications

  • A new class of membrane-bound chemokine with a CX3C motif

    J F Bazan;K B Bacon;G Hardiman;W Wang

  • Position-independent, high-level expression of the human β-globin gene in transgenic mice

    Frank Grosveld;Greet Blom van Assendelft;David R. Greaves;George Kollias

  • Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation

    Divya Vats;Lata Mukundan;Justin I. Odegaard;Lina Zhang

  • Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).

    Kyle J. Garton;Peter J. Gough;Carl P. Blobel;Gillian Murphy

  • Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

    Fernando O. Martinez;Laura Helming;Ronny Milde;Audrey Varin

  • Identification of Novel, Functional Genetic Variants in the Human Matrix Metalloproteinase-2 Gene: ROLE OF Sp1 IN ALLELE-SPECIFIC TRANSCRIPTIONAL REGULATION

    Simon J. Price;David R. Greaves;Hugh Watkins

  • Synthetic chemerin-derived peptides suppress inflammation through ChemR23.

    Jenna L. Cash;Rosie Hart;Andreas Russ;John P.C. Dixon

  • Human CD2 3′-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

    David R. Greaves;Frank D. Wilson;Georgina Lang;Dimitris Kioussis

  • CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

    David R. Greaves;Wei Wang;Daniel J. Dairaghi;Marie Caroline Dieu

  • A dominant control region from the human β-globin locus conferring integration site-independent gene expression

    Dale Talbot;Philip Collis;Michael Antoniou;Miguel Vidal

  • Programmed gene rearrangements altering gene expression.

    P Borst;Greaves

  • Importance of globin gene order for correct developmental expression.

    Olivia Hanscombe;David Whyatt;Peter Fraser;Nikos Yannoutsos

  • CC Chemokine Receptors and Chronic Inflammation—Therapeutic Opportunities and Pharmacological Challenges

    Gemma E. White;Asif J. Iqbal;David R. Greaves

  • The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges

    David R. Greaves;Siamon Gordon

  • PPARγ activation in adipocytes is sufficient for systemic insulin sensitization

    Shigeki Sugii;Peter Olson;Peter Olson;Dorothy D. Sears;Maziyar Saberi

  • TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism.

    John Crawford Welch;Laure Escoubet-Lozach;David Brian Sykes;Kate Liddiard

  • Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice

    Mohammed Qatanani;Nava R. Szwergold;David R. Greaves;Rexford S. Ahima

  • Magnetic Resonance Imaging of Endothelial Adhesion Molecules in Mouse Atherosclerosis Using Dual-Targeted Microparticles of Iron Oxide

    Martina A. McAteer;Jurgen E. Schneider;Ziad A. Ali;Nicholas Warrick

  • Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair

    Filipa C. Simões;Thomas J. Cahill;Amy Kenyon;Daria Gavriouchkina;Daria Gavriouchkina

  • Oxidative metabolism and PGC-1 beta attenuate macrophage-mediated inflammation

    D Vats;L Mukundan;J I Odegaard;L Zhang

Frequent Co-Authors

Keith M. Channon
Keith M. Channon University of Oxford
Siamon Gordon
Siamon Gordon University of Oxford
Peter J. Gough
Peter J. Gough Inzen Therapeutics
Paul R. Riley
Paul R. Riley University of Oxford
Frank Grosveld
Frank Grosveld Erasmus University Rotterdam
Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland
Edward A. Fisher
Edward A. Fisher New York University
Thomas J. Schall
Thomas J. Schall ChemoCentryx (United States)
Yanhua Hu
Yanhua Hu King's College London
Harris Perlman
Harris Perlman Northwestern University

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