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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
11994
World Ranking
9369
National Ranking
716

Overview

Yanhua Hu is affiliated with King's College London in the United Kingdom. Their research spans key areas within medicine and biochemistry, genetics, and molecular biology, with a substantial focus on molecular biology, immunology, surgery, genetics, and oncology.

Their scholarly output includes studies on a broad range of biomedical topics, with particular attention to angiogenesis and VEGF in cancer, lymphatic system and diseases, inflammatory bowel disease, plant and fungal species descriptions, diabetes, cardiovascular risks and lipoproteins, atherosclerosis and cardiovascular diseases, and SARS-CoV-2 and COVID-19 research.

Frequent coauthors in their publications include:

  • Qingbo Xu
  • Rachel Maddux
  • Chun-Ying Wu
  • Sarah Harris

The venues most commonly publishing their work include:

  • The American Journal of Gastroenterology
  • Annals of the Rheumatic Diseases
  • Circulation Research
  • Cellular and Molecular Life Sciences
  • Arteriosclerosis Thrombosis and Vascular Biology

Representative recent papers with year of publication and venue are:

  • "Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial," 2020, Cancer Cell
  • "The Transcriptome of Paired Major and Minor Salivary Gland Tissue in Patients With Primary Sjögren's Syndrome," 2021, Frontiers in Immunology
  • "Hyaluronan promotes the regeneration of vascular smooth muscle with potent contractile function in rapidly biodegradable vascular grafts," 2020, Biomaterials
  • "Molecular and clinical effects of selective tyrosine kinase 2 inhibition with deucravacitinib in psoriasis," 2021, Journal of Allergy and Clinical Immunology
  • "Nonbone Marrow CD34 + Cells Are Crucial for Endothelial Repair of Injured Artery," 2021, Circulation Research

Yanhua Hu's work reflects interdisciplinary collaboration across medicine and molecular biology specialties, evidenced both by the diverse research topics and the range of publication venues. Their research covers clinical, biological, and pathological aspects of disease mechanisms, with emphasis on both immune-related and cardiovascular conditions as well as cancer biology.

Best Publications

  • Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice

    Yanhua Hu;Zhongyi Zhang;Evelyn Torsney;Ali R. Afzal

  • HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells

    Lingfang Zeng;Qingzhong Xiao;Andriana Margariti;Zhongyi Zhang

  • Activation of PDGF receptor α in vascular smooth muscle cells by mechanical stress

    Yanhua Hu;Güunther Böck;Georg Wick;Qingbo Xu

  • Exacerbated vein graft arteriosclerosis in protein kinase Cδ–null mice

    Michael Leitges;Manuel Mayr;Ursula Braun;Ursula Mayr

  • Endothelial Replacement and Angiogenesis in Arteriosclerotic Lesions of Allografts Are Contributed by Circulating Progenitor Cells

    Yanhua Hu;Fergus Davison;Zhongyi Zhang;Qingbo Xu

  • Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

    Andriana Margariti;Bernhard Winkler;Eirini Karamariti;Anna Zampetaki

  • Cyclic Strain Stress-induced Mitogen-activated Protein Kinase (MAPK) Phosphatase 1 Expression in Vascular Smooth Muscle Cells Is Regulated by Ras/Rac-MAPK Pathways

    Chaohong Li;Yanhua Hu;Manuel Mayr;Qingbo Xu

  • XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation

    Andriani Margariti;Hongling Li;Ting Chen;Daniel Martin

  • Circulating Progenitor Cells Regenerate Endothelium of Vein Graft Atherosclerosis, Which Is Diminished in ApoE-Deficient Mice

    Qingbo Xu;Zhongyi Zhang;Fergus Davison;Yanhua Hu

  • Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow

    Lingfang Zeng;Anna Zampetaki;Andriana Margariti;Anna Elena Pepe

  • Both Donor and Recipient Origins of Smooth Muscle Cells in Vein Graft Atherosclerotic Lesions

    Yanhua Hu;Manuel Mayr;Bernhard Metzler;Martin Erdel

  • Smooth Muscle Cells in Transplant Atherosclerotic Lesions Are Originated From Recipients, but Not Bone Marrow Progenitor Cells

    Yanhua Hu;Fergus Davison;Burkhard Ludewig;Martin Erdel

  • Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases

    Manuel Mayr;Chaohong Li;Yiping Zou;Ursula Huemer

  • Rapid Endothelial Turnover in Atherosclerosis-Prone Areas Coincides With Stem Cell Repair in Apolipoprotein E–Deficient Mice

    Georgios Foteinos;Yanhua Hu;Qingzhong Xiao;Bernhard Metzler

  • Mechanical stress-induced DNA damage and rac-p38MAPK signal pathways mediate p53-dependent apoptosis in vascular smooth muscle cells

    Manuel Mayr;Yanhua Hu;Pierre Hainaut;Qingbo Xu

  • Proteomic and Metabolomic Analyses of Atherosclerotic Vessels From Apolipoprotein E-Deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism

    Manuel Mayr;Yuen-Li Chung;Ursula Mayr;Xiaoke Yin

  • Endothelial progenitor cells, cardiovascular risk factors, cytokine levels and atherosclerosis--results from a large population-based study.

    Qingzhong Xiao;Stefan Kiechl;Seema Patel;Friedrich Oberhollenzer

  • Histone Deacetylase 3 Is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow

    Anna Zampetaki;Lingfang Zeng;Andriana Margariti;Qingzhong Xiao

  • Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased dna damage and senescence

    Koralia E. Paschalaki;Richard D. Starke;Yanhua Hu;Nicolas Mercado

  • Transdifferentiated Human Vascular Smooth Muscle Cells are a New Potential Cell Source for Endothelial Regeneration.

    Xuechong Hong;Andriana Margariti;Alexandra Le Bras;Laureen Jacquet

Frequent Co-Authors

Qingbo Xu
Qingbo Xu King's College London
Qingzhong Xiao
Qingzhong Xiao Queen Mary University of London
Manuel Mayr
Manuel Mayr King's College London
Keith M. Channon
Keith M. Channon University of Oxford
David R. Greaves
David R. Greaves University of Oxford
Alan W. Stitt
Alan W. Stitt Queen's University Belfast
Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
Christof Niehrs
Christof Niehrs German Cancer Research Center
Shu Chien
Shu Chien University of California, San Diego
Bin Zhou
Bin Zhou Chinese Academy of Sciences

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