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Genetics

D-Index
48
Citations
7232
World Ranking
4069
National Ranking
1753

Overview

Vicki Huff is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with an emphasis on molecular biology as evidenced by the volume of publications in this subfield.

The scientist's work covers several specialized topics, including:

  • Renal and related cancers
  • Epigenetics and DNA methylation
  • Genetic and kidney cyst diseases
  • Reproductive biology and fertility
  • Prenatal screening and diagnostics
  • Chromatin remodeling and cancer
  • Gestational trophoblastic disease studies

Vicki Huff has contributed to multiple studies and papers published in various peer-reviewed venues. Key publications include:

  • Genetic changes associated with relapse in favorable histology Wilms tumor: A Children's Oncology Group AREN03B2 study, 2022, Cell Reports Medicine
  • Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children's Oncology Group AREN18B5-Q, 2023, Nature Communications
  • Hallmark discoveries in the biology of Wilms tumour, 2023, Nature Reviews Urology
  • Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse, 2024, Differentiation
  • Rhabdoid Tumor of the Kidney and Soft Tissues: Results from National Wilms Tumor Study-5 and Children's Oncology Group Study AREN0321, 2024, Pediatric Blood & Cancer

The scientist frequently collaborates with several coauthors, including Conrad V. Fernandez, Elizabeth A. Mullen, Lindsay A. Renfro, Elizabeth J. Perlman, and Jeffrey S. Dome.

Publication venues where Vicki Huff's research often appears include:

  • Cell Reports Medicine
  • Nature Communications
  • Nature Reviews Urology
  • Differentiation
  • Pediatric Blood & Cancer

Best Publications

  • Loss of Heterozygosity for Chromosomes 1p and 16q Is an Adverse Prognostic Factor in Favorable-Histology Wilms Tumor: A Report From the National Wilms Tumor Study Group

    Paul E. Grundy;Norman E. Breslow;Sierra Li;Elizabeth Penman

  • Loss of heterozygosity for chromosomes 16q and 1p in Wilms' tumors predicts an adverse outcome

    Paul E. Grundy;Perry E. Telzerow;Norman Breslow;Jamie Moksness

  • A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

    Samantha Gadd;Vicki Huff;Amy L. Walz;Ariadne H.A.G. Ooms

  • Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

    Amy L. Walz;Ariadne Ooms;Samantha Gadd;Daniela S. Gerhard

  • The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.

    Fei Gao;Sourindra Maiti;Nargis Alam;Zhen Zhang

  • Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13

    Vicki Huff;Duane A. Compton;Lian Yu Chao;Louise C. Strong

  • Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

    E. Cristy Ruteshouser;Stephen M. Robinson;Vicki D Huff

  • Frequent Association of β-Catenin and WT1 Mutations in Wilms Tumors

    Sourindra Maiti;Rita Alam;Christopher I. Amos;Vicki Huff

  • Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT.

    Vicki Huff;Hiroshi Miwa;Daniel A. Haber;Katherine M. Call

  • Wt1 negatively regulates Β-catenin signaling during testis development

    Hao Chang;Fei Gao;Florian Guillou;Makoto M. Taketo

  • Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development.

    Brigitte Royer-Pokora;Manfred Beier;Markus Henzler;Rita Alam

  • Treatment With Nephrectomy Only for Small, Stage I/Favorable Histology Wilms’ Tumor: A Report From the National Wilms’ Tumor Study Group

    D. M. Green;N. E. Breslow;J. B. Beckwith;M. L. Ritchey

  • Children's Oncology Group's 2013 blueprint for research: Renal tumors

    Jeffrey S. Dome;Conrad V. Fernandez;Elizabeth A. Mullen;John A. Kalapurakal

  • Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group.

    Marcio Malogolowkin;Cecilia A. Cotton;Cecilia A. Cotton;Daniel M. Green;Daniel M. Green;Norman E. Breslow;Norman E. Breslow

  • Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

    Silvestre Vicent;Ron Chen;Leanne C. Sayles;Chenwei Lin

  • The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.

    Xiao Na Wang;Ze Song Li;Ze Song Li;Yu Ren;Tao Jiang

  • Linkage of Familial Wilms' Tumor Predisposition to Chromosome 19 and a Two-Locus Model for the Etiology of Familial Tumors

    J. Matthew McDonald;Edwin C. Douglass;Ross Fisher;Clementina F. Geiser

  • Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1.

    Max J. Coppes;Vicki D Huff;Jerry Pelletier

  • Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

    Qianghua Hu;Fei Gao;Weihua Tian;E. Cristy Ruteshouser

  • Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: a report from the National Wilms Tumor Study Group.

    Daniel M. Green;Daniel M. Green;Cecilia A. Cotton;Marcio Malogolowkin;Norman E. Breslow

Frequent Co-Authors

Elizabeth J. Perlman
Elizabeth J. Perlman Northwestern University
Louise C. Strong
Louise C. Strong The University of Texas MD Anderson Cancer Center
Grady F. Saunders
Grady F. Saunders The University of Texas MD Anderson Cancer Center
Marco A. Marra
Marco A. Marra University of British Columbia
Julie M. Gastier-Foster
Julie M. Gastier-Foster Baylor College of Medicine
Robert C. Shamberger
Robert C. Shamberger Boston Children's Hospital
Malcolm A. Smith
Malcolm A. Smith National Institutes of Health
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
J. Bruce Beckwith
J. Bruce Beckwith Loma Linda University
David A. Wheeler
David A. Wheeler Baylor College of Medicine

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