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D-Index & Metrics

Medicine

D-Index
87
Citations
39948
World Ranking
13423
National Ranking
6826

Overview

Malcolm A. Smith is affiliated with the National Institutes of Health in the United States. Their research primarily revolves around medicine and biochemistry, genetics, and molecular biology, with a total of 158 and 63 publications in these fields respectively. Within these broad categories, Smith focuses on several subfields including molecular biology, neurology, oncology, genetics, and pulmonary and respiratory medicine.

The scientist's main topics of investigation cover areas such as neuroblastoma research and treatments, CAR-T cell therapy research, acute lymphoblastic leukemia research, sarcoma diagnosis and treatment, cancer therapeutics and mechanisms, glioma diagnosis and treatment, and the quality of life of childhood cancer survivors.

  • Neuroblastoma Research and Treatments
  • CAR-T cell therapy research
  • Acute Lymphoblastic Leukemia research
  • Sarcoma Diagnosis and Treatment
  • Cancer therapeutics and mechanisms
  • Glioma Diagnosis and Treatment
  • Childhood Cancer Survivors' Quality of Life

Smith has contributed to multiple research papers in high-impact venues. Some recent notable publications include:

  • Selumetinib in Children with Inoperable Plexiform Neurofibromas, 2020, New England Journal of Medicine
  • The genomic landscape of pediatric acute lymphoblastic leukemia, 2022, Nature Genetics
  • Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032, 2021, Clinical Cancer Research
  • A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study, 2021, Neuro-Oncology
  • The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models, 2021, Clinical Cancer Research

Frequent co-authors with whom Malcolm A. Smith has collaborated extensively include Beverly A. Teicher, Stephen W. Erickson, Raushan T. Kurmasheva, Eric J. Earley, and Richard Görlick. Their collaborative efforts have resulted in a significant number of joint publications across various cancer research topics.

  • Beverly A. Teicher
  • Stephen W. Erickson
  • Raushan T. Kurmasheva
  • Eric J. Earley
  • Richard Görlick

The most frequent publication venues for Smith's work are Cancer Research, European Journal of Cancer, Pediatric Blood & Cancer, Journal of Clinical Oncology, and Neuro-Oncology. This distribution reflects a consistent focus on cancer and pediatric oncology studies.

  • Cancer Research
  • European Journal of Cancer
  • Pediatric Blood & Cancer
  • Journal of Clinical Oncology
  • Neuro-Oncology

In addition to journal publications, Smith has contributed to book literature, including a work titled "Hats," published by Michigan State University Press in 2020.

Best Publications

  • Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

    Alice L. Yu;Andrew L. Gilman;M. Fevzi Ozkaynak;Wendy B. London

  • Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

    MA Smith;S Makino;R Kvetnansky;RM Post

  • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.

    Charles G Mullighan;Xiaoping Su;Jinghui Zhang;Ina Radtke

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • Outcomes for Children and Adolescents With Cancer: Challenges for the Twenty-First Century

    Malcolm A. Smith;Nita L. Seibel;Sean F. Altekruse;Lynn A.G. Ries

  • The genetic landscape of high-risk neuroblastoma

    Trevor J Pugh;Olena Morozova;Edward F Attiyeh;Edward F Attiyeh;Shahab Asgharzadeh;Shahab Asgharzadeh

  • The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

    Yu Liu;John Easton;Ying Shao;Jamie Maciaszek

  • Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

    Xiaotu Ma;Yu Liu;Yanling Liu;Ludmil B. Alexandrov

  • The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions

    Hamid Bolouri;Jason E Farrar;Timothy Triche;Rhonda E Ries

  • Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

    Kathryn G. Roberts;Ryan D. Morin;Jinghui Zhang;Martin Hirst

  • Study design and cohort characteristics of the Childhood Cancer Survivor Study: a multi-institutional collaborative project.

    Leslie L. Robison;Ann C. Mertens;John D. Boice;Norman E. Breslow

  • Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia

    Richard C. Harvey;Richard C. Harvey;Charles G. Mullighan;I-Ming Chen;I-Ming Chen;Walker Wharton

  • JAK mutations in high-risk childhood acute lymphoblastic leukemia.

    Charles G. Mullighan;Jinghui Zhang;Richard C. Harvey;J. Racquel Collins-Underwood

  • Declining childhood and adolescent cancer mortality.

    Malcolm A. Smith;Sean F. Altekruse;Peter C. Adamson;Gregory H. Reaman

  • Retinoids in cancer therapy.

    Malcolm A. Smith;David R. Parkinson;Bruce D. Cheson;Michael A. Friedman

  • Cancer surveillance series [corrected]: brain and other central nervous system cancers: recent trends in incidence and mortality.

    Legler Jm;Ries La;Smith Ma;Warren Jl

  • Cancer Surveillance Series: Recent Trends in Childhood Cancer Incidence and Mortality in the United States

    Martha S. Linet;Lynn A. G. Ries;Malcolm A. Smith;Robert E. Tarone

  • Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome.

    Richard C. Harvey;Richard C. Harvey;Charles G. Mullighan;Xuefei Wang;Kevin K. Dobbin

  • Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

    Thomas F Eleveld;Derek A Oldridge;Virginie Bernard;Jan Koster

  • The pediatric preclinical testing program: description of models and early testing results.

    Peter J. Houghton;Christopher L. Morton;Chandra Tucker;Debbie Payne

Frequent Co-Authors

Peter J. Houghton
Peter J. Houghton The University of Texas Health Science Center at San Antonio
John M. Maris
John M. Maris Children's Hospital of Philadelphia
Richard Gorlick
Richard Gorlick The University of Texas MD Anderson Cancer Center
C. Patrick Reynolds
C. Patrick Reynolds Texas Tech University Health Sciences Center
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Julie M. Gastier-Foster
Julie M. Gastier-Foster Baylor College of Medicine
Todd A. Alonzo
Todd A. Alonzo University of Southern California
Marco A. Marra
Marco A. Marra University of British Columbia
Stephen P. Hunger
Stephen P. Hunger University of Pennsylvania
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital

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