D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 14,431 153 World Ranking 6985 National Ranking 3242

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Internal medicine
  • DNA

Pamela L. Zeitlin spends much of her time researching Cystic fibrosis, Cystic fibrosis transmembrane conductance regulator, Internal medicine, Molecular biology and Genetic enhancement. Her Cystic fibrosis research is multidisciplinary, incorporating perspectives in Phenylbutyrate, Immunology, Pathology, Chloride channel and Bronchoalveolar lavage. Her studies deal with areas such as Secretion and Protein kinase A as well as Cystic fibrosis transmembrane conductance regulator.

Pamela L. Zeitlin combines subjects such as Gastroenterology, Placebo and Endocrinology with her study of Internal medicine. The various areas that she examines in her Molecular biology study include Cell culture and Endoplasmic reticulum. Her research in Genetic enhancement focuses on subjects like Adeno-associated virus, which are connected to Gene expression and Virus.

Her most cited work include:

  • Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. (507 citations)
  • Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR (393 citations)
  • Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter (384 citations)

What are the main themes of her work throughout her whole career to date?

Pamela L. Zeitlin focuses on Cystic fibrosis, Internal medicine, Cystic fibrosis transmembrane conductance regulator, Endocrinology and Molecular biology. Her Cystic fibrosis research is multidisciplinary, incorporating elements of Mutation, Chloride channel, Immunology and Pathology. Her research integrates issues of Gastroenterology, Placebo and Surgery in her study of Internal medicine.

Her work deals with themes such as Phenylbutyrate, Genetic enhancement, Mutant and Cell biology, which intersect with Cystic fibrosis transmembrane conductance regulator. Her Endocrinology research integrates issues from Epithelium, Western blot and In vivo. Her Molecular biology study integrates concerns from other disciplines, such as Cell culture, Immunocytochemistry, Adeno-associated virus, Gene expression and Antibody.

She most often published in these fields:

  • Cystic fibrosis (59.06%)
  • Internal medicine (33.92%)
  • Cystic fibrosis transmembrane conductance regulator (29.82%)

What were the highlights of her more recent work (between 2010-2021)?

  • Cystic fibrosis (59.06%)
  • Internal medicine (33.92%)
  • Cell biology (18.13%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Cystic fibrosis, Internal medicine, Cell biology, Cystic fibrosis transmembrane conductance regulator and Immunology. The concepts of her Cystic fibrosis study are interwoven with issues in Molecular biology, Lung, Mucociliary clearance and Pathology. Her Internal medicine research incorporates themes from Gastroenterology, Chloride channel, Endocrinology and Placebo.

Her biological study spans a wide range of topics, including Ubiquitin, Respiratory epithelium and Mutation. Her Cystic fibrosis transmembrane conductance regulator research incorporates elements of Frameshift mutation, Missense mutation, Bronchiectasis and Exocrine pancreatic insufficiency. Her study in Immunology is interdisciplinary in nature, drawing from both Bronchoalveolar lavage and Microbiology.

Between 2010 and 2021, her most popular works were:

  • Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial (225 citations)
  • Airway microbiota across age and disease spectrum in cystic fibrosis (99 citations)
  • N-acetylcysteine Enhances Cystic Fibrosis Sputum Penetration and Airway Gene Transfer by Highly Compacted DNA Nanoparticles (69 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • DNA

Her main research concerns Cystic fibrosis, Internal medicine, Cystic fibrosis transmembrane conductance regulator, Lung and Chloride channel. She interconnects Endocrinology, Respiratory epithelium, Intensive care medicine, Mucociliary clearance and Nasal administration in the investigation of issues within Cystic fibrosis. Her Nasal administration research includes themes of Molecular biology, Gene expression and Genetic enhancement.

The Internal medicine study combines topics in areas such as Placebo, Tobramycin and Ataluren. Her Cystic fibrosis transmembrane conductance regulator study combines topics from a wide range of disciplines, such as Drug metabolism and Mechanism of action. Her Lung research is multidisciplinary, relying on both Immunology and Microbiology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Terence R. Flotte;Sandra A. Afione;Carol Conrad;Sharon A. McGrath.
Proceedings of the National Academy of Sciences of the United States of America (1993)

704 Citations

Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

Marie Egan;Terence Flotte;Terence Flotte;Sandra Afione;Rikki Solow.
Nature (1992)

513 Citations

Immunocytochemical localization of the cystic fibrosis gene product CFTR.

Isabelle Crawford;Peter C. Maloney;Pamela L. Zeitlin;William B. Guggino.
Proceedings of the National Academy of Sciences of the United States of America (1991)

498 Citations

A pilot clinical trial of oral sodium 4-phenylbutyrate (Buphenyl) in deltaF508-homozygous cystic fibrosis patients: partial restoration of nasal epithelial CFTR function.

Ronald C. Rubenstein;Pamela L. Zeitlin.
American Journal of Respiratory and Critical Care Medicine (1998)

478 Citations

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

Benjamin C. Tang;Michelle Dawson;Michelle Dawson;Samuel K. Lai;Ying Ying Wang.
Proceedings of the National Academy of Sciences of the United States of America (2009)

475 Citations

Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter

Terence R. Flotte;Sandra A. Afione;Rikki Solow;Mitchell L. Drumm.
Journal of Biological Chemistry (1993)

471 Citations

In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.

Ronald C. Rubenstein;Marie E. Egan;Pamela L. Zeitlin.
Journal of Clinical Investigation (1997)

469 Citations

A Cystic Fibrosis Bronchial Epithelial Cell Line: Immortalization by Adeno-12-SV40 Infection

P. L. Zeitlin;L. Lu;J. Rhim;G. Cutting.
American Journal of Respiratory Cell and Molecular Biology (1991)

448 Citations

Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis.

Ronald L. Gibson;Julia Emerson;Sharon McNamara;Jane L. Burns.
American Journal of Respiratory and Critical Care Medicine (2003)

378 Citations

Sodium 4-phenylbutyrate downregulates Hsc70: implications for intracellular trafficking of ΔF508-CFTR

Ronald C. Rubenstein;Pamela L. Zeitlin.
American Journal of Physiology-cell Physiology (2000)

370 Citations

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