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Johan E. van Lier

Johan E. van Lier

D-Index & Metrics

Chemistry

D-Index
60
Citations
10274
World Ranking
9908
National Ranking
263

Overview

Johan E. van Lier is affiliated with the Université de Sherbrooke in Canada. Their primary research lies within the field of Materials Science, with a specialized focus on Materials Chemistry. Additional subfields include Organic Chemistry, Biomedical Engineering, Spectroscopy, and Surgery.

The scientist's work spans several main topics related to crystallography and chemistry. These topics include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Luminescence and Fluorescent Materials
  • Porphyrin and Phthalocyanine Chemistry
  • Nanoplatforms for cancer theranostics
  • Molecular Sensors and Ion Detection
  • Cholesterol and Lipid Metabolism

van Lier has published extensively, with notable papers such as:

  • Synthesis, spectral and crystal structures of gem-dibromovinyl boron dipyrrins, 2020, published in Dyes and Pigments
  • Pd-Catalyzed Sonogashira Cross-Coupling Reactions of gem-Dibromovinyl BODIPY Derivatives, 2021, published in European Journal of Organic Chemistry
  • Pd-catalyzed synthesis of C-C (Sonogashira, Suzuki, Heck, Stille), C-P and C-S linked products using gem -dibromovinyl BODIPY, 2021, published in Journal of Porphyrins and Phthalocyanines
  • X-ray structure analysis of the cholesterol 25- and 20-hydroperoxides, the elusive primary sidechain autoxidation products of cholesterol, 2022, published in Steroids
  • Synthesis of 2',2'-dibromovinyl porphyrins and their versatile use in Pd-catalyzed cross-coupling reactions, 2025, published in Tetrahedron

Their frequent coauthors include Hesham Ali and Brigitte Guérin, with whom they have collaborated on multiple publications.

van Lier's work has been published in a variety of scientific venues. Most frequent publishing sites are:

  • The Cambridge Structural Database
  • European Journal of Organic Chemistry
  • Dyes and Pigments
  • Journal of Porphyrins and Phthalocyanines
  • Steroids

Best Publications

  • Current status of phthalocyanines in the photodynamic therapy of cancer

    Cynthia M. Allen;Wesley M. Sharman;Johan E. Van Lier

  • Targeted photodynamic therapy via receptor mediated delivery systems.

    Wesley M Sharman;Johan E van Lier;Cynthia M Allen

  • Photosensitizing activity of water- and lipid-soluble phthalocyanines on Escherichia coli.

    Giulio Bertolini;Francesca Rossi;Giuliana Valduga;Giulio Jori

  • Sterol metabolism. XX. Cholesterol 7.beta.-hydroperoxide

    Jon I. Teng;Martin J. Kulig;Leland L. Smith;Gordon Kan

  • Sterol metabolism. VII. Autoxidation of cholesterol via hydroperoxide intermediates

    Johan E. Van Lier;Leland Leroy. Smith

  • Biological activities of phthalocyanines. IX: Photosensitization of V-79 Chinese hamster cells and EMT-6 mouse mammary tumor by selectively sulfonated zinc phthalocyanines

    Nicole Brasseur;Hasrat Ali;Réjean Langlois;Johan E. Van Lier

  • Photosensitized reactions of nucleic acids.

    Unknown

  • Phthalocyanine-peptide conjugates: receptor-targeting bifunctional agents for imaging and photodynamic therapy.

    Elena Ranyuk;Nicole Cauchon;Klaus Klarskov;Brigitte Guérin

  • PEG-coated Poly(lactic acid) Nanoparticles for the Delivery of Hexadecafluoro Zinc Phthalocyanine to EMT-6 Mouse Mammary Tumours

    Eric Allemann;Nicole Brasseur;Ouhida Benrezzak;Jacques Rousseau

  • Structure‐Photodynamic Activity Relationships of a Series of 4‐Substituted Zinc Phthalocyanines

    Philippe Margaron;Marie‐Josée Grégoire;Vladimir Ŝĉasnár;Hasrat Ali

  • Azaanalogs of phthalocyanine: syntheses and properties

    Svetlana V. Kudrevich;Johan E. van Lier

  • PHTHALOCYANINE AND NAPHTHALOCYANINE PHOTOSENSITIZED OXIDATION OF 2′‐DEOXYGUANOSINE: DISTINCT TYPE I AND TYPE II PRODUCTS

    J.-L. Ravanat;M. Berger;F. Benard;R. Langlois

  • BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES‐X. SYNTHESES AND ANALYSES OF SULFONATED PHTHALOCYANINES

    Unknown

  • BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—V. PHOTODYNAMIC THERAPY OF EMT-6 MAMMARY TUMORS IN MICE WITH SULFONATED PHTHALOCYANINES

    Nicole Brasseur;Hasrat Ali;Réjean Langlois;J. Richard Wagner

  • Structure-photodynamic activity relationships of substituted zinc trisulfophthalocyanines.

    Nicole Cauchon;Hongjian Tian;Réjean Langlois;Carole La Madeleine

  • BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES—IV. TYPE II SENSITIZED PHOTOOXIDATION OF L‐TRYPTOPHAN AND CHOLESTEROL BY SULFONATED METALLO PHTHALOCYANINES

    Unknown

  • Photodynamic therapy of tumours with hexadecafluoro zinc phthalocyanine formulated in PEG‐coated poly(lactic acid) nanoparticles

    Eric Allémann;Eric Allémann;Jacques Rousseau;Nicole Brasseur;Svetlana V. Kudrevich

  • TaBr5-catalyzed Biginelli reaction: one-pot synthesis of 3,4-dihydropyrimidin-2-(1H)-ones/thiones under solvent-free conditions

    Naseem Ahmed;Johan E. van Lier

  • PHTHALOCYANINE AND NAPHTHALOCYANINE PHOTOSENSITIZED OXIDATION OF 2′-DEOXYGUANOSINE

    J.‐L. Ravanat;M. Berger;F. Benard;R. Langlois

  • Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings

    Wesley M. Sharman;Svetlana V. Kudrevich;Johan E. van Lier

  • Receptor-mediated targeting of phthalocyanines to macrophages via covalent coupling to native or maleylated bovine serum albumin.

    Nicole Brasseur;Réjean Langlois;Carole La Madeleine;René Ouellet

  • Biological activities of phthalocyanines--VII. Photoinactivation of V-79 Chinese hamster cells by selectively sulfonated gallium phthalocyanines.

    Nicole Brasseur;Hasrat Ali;Rejean Langlois;Johan E. Van Lier

  • Quantitative structure-activity relationships/comparative molecular field analysis (QSAR/CoMFA) for receptor-binding properties of halogenated estradiol derivatives.

    Tsvetan G. Gantchev;Hasrat Ali;Johan E. van Lier

Frequent Co-Authors

David Dolphin
David Dolphin University of British Columbia
Pirjo Nuutila
Pirjo Nuutila Turku University Hospital
Sébastien Tremblay
Sébastien Tremblay Université Laval
Robert Gurny
Robert Gurny University of Geneva
Volker Hessel
Volker Hessel University of Adelaide
Geoffrey L. Hammond
Geoffrey L. Hammond University of British Columbia
André Pèlegrin
André Pèlegrin University of Montpellier
Peter ten Dijke
Peter ten Dijke Leiden University Medical Center
Manfred M. Kappes
Manfred M. Kappes Karlsruhe Institute of Technology

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