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Biology and Biochemistry

D-Index
90
Citations
22760
World Ranking
2483
National Ranking
179

Overview

Karl Kunzelmann is affiliated with the University of Regensburg in Germany. Their research spans several interconnected fields primarily within Medicine and Biochemistry, Genetics and Molecular Biology.

The main areas of study for Kunzelmann include:

  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Physiology
  • Genetics
  • Pathology and Forensic Medicine

Kunzelmann's work focuses significantly on topics such as:

  • Ion channel regulation and function
  • Cystic Fibrosis Research Advances
  • Neonatal Respiratory Health Research
  • Ion Transport and Channel Regulation
  • Asthma and respiratory diseases
  • Genetic and Kidney Cyst Diseases
  • Biomedical Research and Pathophysiology

The scientist has contributed frequently to various publication venues. The most common include:

  • International Journal of Molecular Sciences
  • Pflügers Archiv - European Journal of Physiology
  • Cell Calcium
  • The FASEB Journal
  • Cells

Among the recent papers authored or co-authored by Kunzelmann are:

  • "Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo," 2020, Nature Communications
  • "Pharmacological Inhibition and Activation of the Ca2+ Activated Cl− Channel TMEM16A," 2020, International Journal of Molecular Sciences
  • "Impaired Renal HCO3 - Excretion in Cystic Fibrosis," 2020, Journal of the American Society of Nephrology
  • "P. aeruginosa Induced Lipid Peroxidation Causes Ferroptotic Cell Death in Airways," 2021, Cellular Physiology and Biochemistry
  • "TMEM16A Mediates Mucus Production in Human Airway Epithelial Cells," 2020, American Journal of Respiratory Cell and Molecular Biology

Karl Kunzelmann has collaborated frequently with several co-authors, including:

  • Rainer Schreiber
  • Jiraporn Ousingsawat
  • Raquel Centeio
  • Khaoula Talbi
  • Inês Cabrita

Best Publications

  • CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells.

    A. L. Cozens;M. J. Yezzi;K. Kunzelmann;T. Ohrui

  • Electrolyte Transport in the Mammalian Colon: Mechanisms and Implications for Disease

    Karl Kunzelmann;Marcus Mall

  • Ion channels and cancer.

    Karl Kunzelmann

  • Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.

    Tobias B. Huber;Bernhard Schermer;Roman Ulrich Müller;Martin Höhne

  • TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

    Umamaheswar Duvvuri;Daniel J. Shiwarski;Dong Xiao;Carol Bertrand

  • Loss of TMEM16A Causes a Defect in Epithelial Ca2+-dependent Chloride Transport

    Jiraporn Ousingsawat;Joana R. Martins;Rainer Schreiber;Jason R. Rock

  • Expression and Function of Epithelial Anoctamins

    Rainer Schreiber;Inna Uliyakina;Patthara Kongsuphol;Richard Warth

  • The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

    M Mall;M Bleich;R Greger;R Schreiber

  • Transfer and Expression of Foreign Genes in Mammalian Cells

    A. Colosimo;K. K. Goncz;A. R. Holmes;K. H. P. Kunzelmann

  • Characteristics of apical chloride channels in human colon cells (HT29).

    John P. Hayslett;Heinz Gögelein;Karl Kunzelmann;Rainer Greger

  • Anoctamins are a family of Ca2+-activated Cl- channels.

    Yuemin Tian;Rainer Schreiber;Karl Kunzelmann

  • TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A.

    Joana Almaça;Yuemin Tian;Fadi Aldehni;Jiraporn Ousingsawat

  • Inhibition of epithelial Na+ currents by intracellular domains of the cystic fibrosis transmembrane conductance regulator.

    K Kunzelmann;G.L Kiser;R Schreiber;J.R Riordan

  • Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis.

    Christian Ruiz;Joana Raquel Martins;Florian Rudin;Sandra Schneider

  • The role of the IsK protein in the specific pharmacological properties of the IKs channel complex

    A. E. Busch;G. L. Busch;E. Ford;H. Suessbrich

  • Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis

    Margarida D. Amaral;Karl Kunzelmann

  • Cholinergic ion secretion in human colon requires coactivation by cAMP

    M. Mall;M. Bleich;M. Schürlein;J. Kühr

  • Wild type but not ΔF508 CFTR inhibits Na+ conductance when coexpressed in Xenopus oocytes

    M. Mall;A. Hipper;R. Greger;K. Kunzelmann

  • Expression of Voltage-Gated Potassium Channels in Human and Mouse Colonic Carcinoma

    Jiraporn Ousingsawat;Melanie Spitzner;Supaporn Puntheeranurak;Luigi Terracciano

  • Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages.

    Jiraporn Ousingsawat;Podchanart Wanitchakool;Arthur Kmit;Ana M. Romao

Frequent Co-Authors

Rainer Schreiber
Rainer Schreiber University of Regensburg
Marcus A. Mall
Marcus A. Mall Charité - University Medicine Berlin
Margarida D. Amaral
Margarida D. Amaral University of Lisbon
Hermann Pavenstädt
Hermann Pavenstädt University of Freiburg
Roland Nitschke
Roland Nitschke University of Freiburg
Daniel Markovich
Daniel Markovich University of Queensland
Kai-Uwe Eckardt
Kai-Uwe Eckardt Charité - University Medicine Berlin
Joachim Kuehr
Joachim Kuehr University of Freiburg
Florian Lang
Florian Lang University of Tübingen
Thomas Benzing
Thomas Benzing University of Cologne

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