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H. Criss Hartzell

H. Criss Hartzell

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
13598
World Ranking
8343
National Ranking
3764

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

H. Criss Hartzell is affiliated with Emory University in the United States and has made contributions primarily in the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work spans multiple subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Cellular and Molecular Neuroscience, and Immunology.

The scientist's main research topics cover a variety of specialized areas, including:

  • Ion channel regulation and function
  • Muscle Physiology and Disorders
  • Cardiac electrophysiology and arrhythmias
  • Blood Coagulation and Thrombosis Mechanisms
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • S100 Proteins and Annexins
  • Ion Channels and Receptors

Hartzell has published extensively, with notable papers including:

  • Myosoft: An automated muscle histology analysis tool using machine learning algorithm utilizing FIJI/ImageJ software, 2020, PLoS ONE
  • ANO5 ensures trafficking of annexins in wounded myofibers, 2021, The Journal of Cell Biology
  • TMEM16E regulates endothelial cell procoagulant activity and thrombosis, 2023, Journal of Clinical Investigation
  • Molecular mechanisms of activation and regulation of ANO1-Encoded Ca2+-Activated Cl- channels, 2021, Channels
  • Phosphatidylserine exposure modulates adhesion GPCR BAI1 (ADGRB1) signaling activity, 2022, Journal of Biological Chemistry

The research has been disseminated through various publication venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • The Journal of Cell Biology
  • UNC Libraries
  • PLoS ONE

Hartzell collaborates frequently with several coauthors, including Kuai Yu, Steven Foltz, Hyo-Jung Choo, Pengfei Liang, and Yui Chun S. Wan. These collaborations reflect a consistent network within their research areas.

Recognition for Hartzell's contributions includes election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • MOLECULAR PHYSIOLOGY OF NOREPINEPHRINE AND SEROTONIN TRANSPORTERS

    R D Blakely;L J De Felice;H C Hartzell

  • Regulation of cardiac ion channels by catecholamines, acetylcholine and second messenger systems.

    H.Criss Hartzell

  • Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

    H C Hartzell;R Fischmeister

  • Molecular Physiology of Bestrophins: Multifunctional Membrane Proteins Linked to Best Disease and Other Retinopathies

    H. Criss Hartzell;Zhiqiang Qu;Kuai Yu;Qinghuan Xiao

  • ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity

    Jiaping Gu;Chi Wai Lee;Yanjie Fan;Daniel Komlos

  • Chloride Channels: Often Enigmatic, Rarely Predictable

    Charity Duran;Christopher H. Thompson;Qinghuan Xiao;H. Criss Hartzell

  • Acetylcholine receptors. Distribution and extrajunctional density in rat diaphragm after denervation correlated with acetylcholine sensitivity

    H. Criss Hartzell;Douglas M. Fambrough

  • Anoctamin/TMEM16 family members are Ca2+‐activated Cl− channels

    H. Criss Hartzell;Kuai Yu;Qinhuan Xiao;Li-Ting Chien

  • Magnesium ions in cardiac function. Regulator of ion channels and second messengers.

    Richard E. White;H.Criss Hartzell

  • Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones

    H. Criss Hartzell;Stephen W. Kuffler;Robert Stickgold;Doju Yoshikami

  • Mechanism of action of acetylcholine on calcium current in single cells from frog ventricle.

    R Fischmeister;H C Hartzell

  • Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop

    Qinghuan Xiao;Kuai Yu;Patricia Perez-Cornejo;Yuanyuan Cui

  • Cyclic guanosine 3',5'-monophosphate regulates the calcium current in single cells from frog ventricle.

    R Fischmeister;H C Hartzell

  • Two Bestrophins Cloned from Xenopus laevis Oocytes Express Ca2+-activated Cl- Currents

    Zhiqiang Qu;Raymond W. Wei;Wesley Mann;H. Criss Hartzell

  • Acetylcholine receptors: number and distribution at neuromuscular junctions in rat diaphragm.

    Douglas M. Fambrough;H. Criss Hartzell

  • Anion Permeation in Ca2+-Activated Cl− Channels

    Zhiqiang Qu;H. Criss Hartzell

  • Bimodal Control of a Ca2+-Activated Cl− Channel by Different Ca2+ Signals

    Akinori Kuruma;H. Criss Hartzell

  • Tmem16A Encodes the Ca2+-activated Cl− Channel in Mouse Submandibular Salivary Gland Acinar Cells

    Victor G. Romanenko;Marcelo A. Catalán;David A. Brown;Ilva Putzier

  • Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology

    Kuai Yu;Charity Duran;Zhiqiang Qu;Yuan-Yuan Cui

  • Identification of a lipid scrambling domain in ANO6/TMEM16F

    Kuai Yu;Jarred M Whitlock;Kyleen Lee;Eric A Ortlund

Frequent Co-Authors

Emad Tajkhorshid
Emad Tajkhorshid University of Illinois at Urbana-Champaign
Victor Faundez
Victor Faundez Emory University
Douglas M. Fambrough
Douglas M. Fambrough Johns Hopkins University
Rodolphe Fischmeister
Rodolphe Fischmeister University of Paris-Saclay
Neal S. Peachey
Neal S. Peachey Cleveland Clinic
Velia M. Fowler
Velia M. Fowler University of Delaware
Randy D. Blakely
Randy D. Blakely Florida Atlantic University
John E. Rash
John E. Rash Colorado State University
Angel L. De Blas
Angel L. De Blas University of Connecticut
Berry Pinshow
Berry Pinshow Ben-Gurion University of the Negev

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