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Biology and Biochemistry

D-Index
57
Citations
10307
World Ranking
13973
National Ranking
5902

Overview

Byron Kemper is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research spans multiple disciplines within the life sciences, predominantly focusing on biochemistry, genetics, and molecular biology, as well as medicine. They have contributed extensively to subfields such as molecular biology, epidemiology, cancer research, oncology, and cellular and molecular neuroscience.

Their research topics cover a range of areas including liver disease diagnosis and treatment, epigenetics and DNA methylation, fibroblast growth factor research, autophagy in disease and therapy, microRNA in disease regulation, RNA research and splicing, and hepatitis B virus studies.

Byron Kemper has published several papers in notable journals. Some of the recent works include:

  • Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase, 2020, Nature Communications
  • Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A, 2020, Nature Communications
  • Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver, 2020, Diabetes
  • BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination, 2020, JCI Insight
  • Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice, 2022, Molecular Metabolism

Byron Kemper frequently collaborates with several researchers. Their notable coauthors include Jongsook Kim Kemper, Hao Sun, Sunmi Seok, Young-Chae Kim, and Jinjing Chen. Their collaboration network reflects a strong focus on molecular mechanisms underpinning metabolic and liver-related diseases.

Their work has been published primarily in journals such as Nature Communications, eLife, Diabetes, JCI Insight, and Molecular Metabolism, with Nature Communications and eLife being the most frequent venues.

Best Publications

  • The P450 gene superfamily: recommended nomenclature.

    Nebert Dw;Adesnik M;Coon Mj;Estabrook Rw

  • Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering.

    David A. Mead;Elzbieta Szczesna-Skorupa;Byron Kemper

  • The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

    Daniel W. Nebert;David R. Nelson;Milton Adesnik;Minor J. Coon

  • Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

    Sung E. Choi;Ting Fu;Sunmi Seok;Dong Hyun Kim

  • Pre-proparathyroid Hormone: A Direct Translation Product of Parathyroid Messenger RNA

    Byron Kemper;Joel F. Habener;Richard C. Mulligan;John T. Potts

  • Proparathyroid hormone: identification of a biosynthetic precursor to parathyroid hormone.

    Byron Kemper;Joel F. Habener;John T. Potts;Alexander Rich

  • A universal approach to the expression of human and rabbit cytochrome P450s of the 2C subfamily in Escherichia coli

    Toby H. Richardson;Frank Jung;Keith J. Griffin;Mike Wester

  • Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region.

    Joel F. Habener;Michael Rosenblatt;Byron Kemper;Henry M. Kronenberg

  • MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function

    Ting Fu;Sunmi Seok;Sunge Choi;Zhang Huang

  • Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide

    Elzbieta Szczesna-Skorupa;Nancy Browne;David Mead;Byron Kemper

  • Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase.

    Sangwon Byun;Sangwon Byun;Sunmi Seok;Young Chae Kim;Yang Zhang

  • Single stranded DNA SP6 promoter plasmids for engineering mutant RNAs and proteins: synthesis of a 'stretched' preproparathyroid hormone.

    David A. Mead;Elzbieta Szczesna Skorupa;Byron Kemper

  • Pre-proparathyroid hormone: analysis of radioactive tryptic peptides and amino acid sequence.

    Byron Kemper;Joel F. Habener;Michael D. Ernst;John T. Potts

  • Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ

    Youngkyu Park;Hong Li;Byron Kemper;Byron Kemper

  • Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form.

    John K. Leighton;Bettina A. DeBrunner-Vossbrinck;Byron Kemper

  • A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

    Dong Hyun Kim;Zhen Xiao;Sanghoon Kwon;Xiaoxiao Sun

  • Parathyroid Secretion: Discovery of a Major Calcium-Dependent Protein

    Byron Kemper;Joel F. Habener;Alexander Rich;John T. Potts

  • Glucocorticoid Receptor-interacting Protein 1 Mediates Ligand-independent Nuclear Translocation and Activation of Constitutive Androstane Receptor in Vivo

    Gyesik Min;J. Kim Kemper;Byron Kemper

  • Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells.

    Elzbieta Szczesna-Skorupa;Bahar Mallah;Byron Kemper

  • Chimeric single-stranded DNA phage-plasmid cloning vectors.

    David A. Mead;Byron Kemper

Frequent Co-Authors

Eric F. Johnson
Eric F. Johnson AbbVie (United States)
H. Eric Xu
H. Eric Xu Chinese Academy of Sciences
Dong-Hyun Kim
Dong-Hyun Kim Kyung Hee University
Joel F. Habener
Joel F. Habener Harvard University
Janardan K. Reddy
Janardan K. Reddy Northwestern University
Minor J. Coon
Minor J. Coon University of Michigan–Ann Arbor
Michael R. Waterman
Michael R. Waterman Vanderbilt University
Milton Adesnik
Milton Adesnik New York University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Daniel W. Nebert
Daniel W. Nebert University of Cincinnati

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