World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
15695
World Ranking
7090
National Ranking
3259

Chemistry

D-Index
71
Citations
15661
World Ranking
5657
National Ranking
1745

James R. Halpert publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where James R. Halpert sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 276 publications — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

James R. Halpert D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James R. Halpert sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 71 D-Index — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

James R. Halpert is affiliated with the University of Connecticut in the United States. Their work spans multiple areas within pharmacology, toxicology, and pharmaceutics, with additional contributions related to medicine.

The scientist's recent publications cover a range of topics primarily focused on pharmacogenetics and drug metabolism. Some notable papers include:

  • Strategies in herbivory by mammals revisited: The role of liver metabolism in a juniper specialist (Neotoma stephensi) and a generalist (Neotoma albigula), 2020, Molecular Ecology
  • Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond, 2022, Drug Metabolism and Disposition
  • Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferences, 2022, Advances in pharmacology
  • The Evolution of Drug Metabolism and Disposition: A Perspective From the Editors, 2022, Drug Metabolism and Disposition
  • So many roads traveled: A career in science and administration, 2020, Journal of Biological Chemistry

These publications often explore cytochrome P450 enzymes, their diversity, structure, and role in drug metabolism, alongside ecological aspects of animal herbivory and metabolism.

Frequent coauthors who have collaborated with James R. Halpert include:

  • Michele M. Skopec
  • P. Ross Wilderman
  • M. Denise Dearing
  • Jeffrey Stevens
  • Teri J. Orr

The researcher has published multiple articles in venues such as:

  • Drug Metabolism and Disposition
  • Journal of Biological Chemistry
  • Molecular Ecology
  • Advances in pharmacology
  • The FASEB Journal

James R. Halpert's main fields of study include pharmacology, toxicology and pharmaceutics, and medicine. Subfields of their research incorporate pharmacology, molecular biology, ecology, pediatrics, perinatology and child health, along with computational theory and mathematics.

The core topics addressed in their work are:

  • Pharmacogenetics and Drug Metabolism
  • Pharmacological Effects and Toxicity Studies
  • Computational Drug Discovery Methods
  • Analytical Chemistry and Chromatography
  • Animal Ecology and Behavior Studies
  • Wildlife Ecology and Conservation
  • Metabolomics and Mass Spectrometry Studies

Best Publications

  • Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

    M D Burke;S Thompson;C R Elcombe;J Halpert

  • The genetic determinants of the CYP3A5 polymorphism

    Elisabeth Hustert;Michael Haberl;Oliver Burk;Renzo Wolbold

  • An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

    Emily E. Scott;You Ai He;Michael R. Wester;Mark A. White

  • Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding.

    Emily E. Scott;Mark A. White;You Ai He;Eric F. Johnson

  • Identification and functional characterization of eight CYP3A4 protein variants.

    Regina Eiselt;Tammy L. Domanski;Arne Zibat;Romy Mueller

  • Analysis of human cytochrome P450 3A4 cooperativity: construction and characterization of a site-directed mutant that displays hyperbolic steroid hydroxylation kinetics.

    Greg R. Harlow;James R. Halpert

  • Selective inhibitors of cytochromes P450.

    J R Halpert;F P Guengerich;J R Bend;M A Correia

  • cDNA cloning and initial characterization of CYP3A43, a novel human cytochrome P450.

    Tammy L. Domanski;Csaba Finta;James R. Halpert;Peter G. Zaphiropoulos

  • TOXICOLOGY OF THIONO-SULFUR COMPOUNDS

    Robert A. Neal;James Halpert

  • Amino acid sequence of a presynaptic neurotoxin from the venom of Notechis scutatus scutatus (Australian tiger snake).

    J Halpert;D Eaker

  • Midazolam oxidation by cytochrome P450 3A4 and active-site mutants: an evaluation of multiple binding sites and of the metabolic pathway that leads to enzyme inactivation

    Kishore K. Khan;You Qun He;Tammy L. Domanski;James R. Halpert

  • Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction.

    Yonghong Zhao;Mark A. White;B.K. Muralidhara;Ling Sun

  • Alanine-scanning mutagenesis of a putative substrate recognition site in human cytochrome P450 3A4. Role of residues 210 and 211 in flavonoid activation and substrate specificity

    Greg R. Harlow;James R. Halpert

  • Analysis of mammalian cytochrome P450 structure and function by site-directed mutagenesis.

    T L Domanski;J R Halpert

  • Molecular modeling of cytochrome P450 3A4

    Grazyna D. Szklarz;James R. Halpert

  • Phenylalanine and tryptophan scanning mutagenesis of CYP3A4 substrate recognition site residues and effect on substrate oxidation and cooperativity.

    Tammy L. Domanski;You-Ai He;Kishore K. Khan;Fabienne Roussel

  • Analysis of Four Residues within Substrate Recognition Site 4 of Human Cytochrome P450 3A4: Role in Steroid Hydroxylase Activity and α-Naphthoflavone Stimulation

    Tammy L. Domanski;Juping Liu;Greg R. Harlow;James R. Halpert

  • A truncation of 2B subfamily cytochromes P450 yields increased expression levels, increased solubility, and decreased aggregation while retaining function.

    Emily E. Scott;Margit Spatzenegger;James R. Halpert

  • Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.

    Huifen Wang;Ryan Dick;Hequn Yin;Estefania Licad-Coles

  • Structural Basis of Selective Cytochrome P450 Inhibition

    James R. Halpert

Frequent Co-Authors

Hong Liu
Hong Liu Shandong University
Eric F. Johnson
Eric F. Johnson AbbVie (United States)
Richard M. Philpot
Richard M. Philpot National Institutes of Health
C. David Stout
C. David Stout Scripps Research Institute
Paul F. Hollenberg
Paul F. Hollenberg University of Michigan–Ann Arbor
Weihua Li
Weihua Li East China University of Science and Technology
David J. Waxman
David J. Waxman Boston University
Rune Toftgård
Rune Toftgård Karolinska Institute
John R. Bend
John R. Bend University of Western Ontario
Dennis R. Koop
Dennis R. Koop Oregon Health & Science University

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