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Chemistry

D-Index
43
Citations
10942
World Ranking
17052
National Ranking
4201

Overview

Ilia G. Denisov is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research primarily focuses on pharmacology, toxicology, and pharmaceutics, with contributions extending into endocrinology, diabetes, metabolism, molecular biology, spectroscopy, and inorganic chemistry.

The scientist's work covers a range of topics, including pharmacogenetics and drug metabolism, hormonal regulation and hypertension, metal-catalyzed oxygenation mechanisms, hormonal and reproductive studies, lipid membrane structure and behavior, advanced biosensing and bioanalysis techniques, and eicosanoids and hypertension pharmacology.

Denisov has authored several papers, notable among them are:

  • Midazolam as a Probe for Drug-Drug Interactions Mediated by CYP3A4: Homotropic Allosteric Mechanism of Site-Specific Hydroxylation, 2021, Biochemistry
  • Midazolam as a Probe for Heterotropic Drug-Drug Interactions Mediated by CYP3A4, 2022, Biomolecules

Other frequently cited papers that relate to their research network include:

  • Nanodiscs: A toolkit for membrane protein science, 2020, Protein Science
  • Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome b5, 2021, Journal of the American Chemical Society

Denisov frequently collaborates with several researchers, including Stephen G. Sligar, Yelena V. Grinkova, James R. Kincaid, Yilin Liu, and Mark A. McLean.

Their publications appear regularly in venues such as Biochemistry, Journal of Inorganic Biochemistry, Cancer Research, Protein Science, and Voprosy Obrazovaniya/ Educational Studies Moscow.

Best Publications

  • Structure and Chemistry of Cytochrome P450

    Ilia G. Denisov;Thomas M. Makris;Stephen G. Sligar;Ilme Schlichting

  • Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size.

    Ilia G Denisov;Yelena V Grinkova;A A Lazarides;Stephen G Sligar

  • Chapter 11 - Reconstitution of membrane proteins in phospholipid bilayer nanodiscs.

    T. K. Ritchie;Y. V. Grinkova;T. H. Bayburt;I. G. Denisov

  • Nanodiscs for structural and functional studies of membrane proteins

    Ilia G Denisov;Stephen G Sligar

  • Nanodiscs in Membrane Biochemistry and Biophysics

    Ilia G. Denisov;Stephen G. Sligar

  • Cooperativity in Cytochrome P450 3A4 LINKAGES IN SUBSTRATE BINDING, SPIN STATE, UNCOUPLING, AND PRODUCT FORMATION

    Ilia G. Denisov;Bradley J. Baas;Yelena V. Grinkova;Stephen G. Sligar

  • Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment.

    Bradley J. Baas;Ilia G. Denisov;Stephen G. Sligar

  • Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers.

    Yelena V. Grinkova;Ilia G. Denisov;Stephen G. Sligar

  • Thermotropic phase transition in soluble nanoscale lipid bilayers.

    Ilia G. Denisov;Mark A. McLean;Andrew W. Shaw;Yelena V. Grinkova

  • Spectroscopic features of cytochrome P450 reaction intermediates.

    Abhinav Luthra;Ilia G. Denisov;Stephen G. Sligar

  • Nanodiscs as a new tool to examine lipid-protein interactions

    Mary A. Schuler;Ilia G. Denisov;Stephen G. Sligar

  • Molecular dynamics simulations of discoidal bilayers assembled from truncated human lipoproteins.

    Amy Y. Shih;Ilia G. Denisov;James C. Phillips;Stephen G. Sligar

  • Nanodiscs: A toolkit for membrane protein science.

    Stephen G. Sligar;Ilia G. Denisov

  • Cooperative properties of cytochromes P450

    Ilia G. Denisov;Daniel J. Frank;Stephen G. Sligar

  • Cryotrapped Reaction Intermediates of Cytochrome P450 Studied by Radiolytic Reduction with Phosphorus-32

    Ilia G. Denisov;Thomas M. Makris;Stephen G. Sligar

  • Cytochromes P450 in Nanodiscs

    Ilia G. Denisov;Stephen G. Sligar

  • The ferrous-dioxygen intermediate in human cytochrome P450 3A4. Substrate dependence of formation and decay kinetics.

    Ilia G. Denisov;Yelena V. Grinkova;Bradley J. Baas;Stephen G. Sligar

  • Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis.

    Stephen G. Sligar;Thomas M. Makris;Ilia G. Denisov

  • Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450

    Ilia G. Denisov;Piotr J. Mak;Thomas M. Makris;Stephen G. Sligar

  • Structural differences between soluble and membrane bound cytochrome P450s

    I. G. Denisov;A. Y. Shih;Stephen Sligar

Frequent Co-Authors

Stephen G. Sligar
Stephen G. Sligar University of Illinois at Urbana-Champaign
James R. Kincaid
James R. Kincaid Marquette University
Thomas L. Poulos
Thomas L. Poulos University of California, Irvine
Gunda I. Georg
Gunda I. Georg University of Minnesota
Jorge H. Capdevila
Jorge H. Capdevila Vanderbilt University
Ian A. Blair
Ian A. Blair University of Pennsylvania
John H. Dawson
John H. Dawson University of South Carolina
Emad Tajkhorshid
Emad Tajkhorshid University of Illinois at Urbana-Champaign
John R. Falck
John R. Falck The University of Texas Southwestern Medical Center
Haitao Chu
Haitao Chu University of Minnesota

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