World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
17025
World Ranking
4646
National Ranking
2250

Overview

Jorge H. Capdevila is affiliated with Vanderbilt University in the United States and focuses their research on several interconnected scientific disciplines. Their work spans the fields of Biochemistry, Genetics and Molecular Biology, Chemistry, and Medicine, contributing to a multidisciplinary understanding of biological and chemical processes.

The scientist's research encompasses specific subfields including Biochemistry, Organic Chemistry, and Endocrinology, Diabetes and Metabolism. These areas provide a foundation for exploring complex biochemical interactions and hormonal regulation mechanisms.

Capdevila's scholarly output includes publications in recognized academic venues. Notably, their work has appeared in Prostaglandins & Other Lipid Mediators, which is a frequent publication venue for their research.

Their recent published paper titled "Epoxyeicosatrienoic acids (EETs): A novel class of second messengers of hormonal functional responses" was released in 2025 within the same journal. This publication addresses molecular signaling processes involving epoxyeicosatrienoic acids.

Research topics covered in their work highlight several thematic areas:

  • Eicosanoids and Hypertension Pharmacology
  • Free Radicals and Antioxidants
  • Hormonal Regulation and Hypertension

Collaboration plays a part in their research activities, with frequent co-authors including John R. Falck and Adeniyi Michael Adebesin. These collaborations indicate integration of expertise across related research domains.

Best Publications

  • Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase

    Jorge H. Capdevila;John R. Falck;Raymond C. Harris

  • Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension

    John D. Imig;Xueying Zhao;Jorge H. Capdevila;Christophe Morisseau

  • Human cytochromes P450

    Julia A Hasler;Ronald Estabrook;Michael Murray;Irina Pikuleva

  • Cytochrome P450 and the arachidonate cascade.

    Jorge H. Capdevila;J R Falck;Ronald W. Estabrook

  • Liver microsomal cytochrome P-450 and the oxidative metabolism of arachidonic acid.

    J Capdevila;N Chacos;J Werringloer;R A Prough

  • Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

    Vijaykumar R. Holla;Fadi Adas;John D. Imig;Xueying Zhao

  • The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands

    L. Ashley Cowart;Shouzuo Wei;Shouzuo Wei;Shouzuo Wei;Mei-Hui Hsu;Eric F. Johnson

  • The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase.

    N. Chacos;J. Capdevila;J. R. Falck;S. Manna

  • Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

    Keiko Makita;Kihito Takahashi;Armando Karara;Harry R. Jacobson

  • Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.

    Jorge Capdevila;Lionel Gil;Miriam Orellana;Lawrence J. Marnett

  • Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase.

    Darryl C. Zeldin;Jun Kobayashi;John R. Falck;Bruce S. Winder

  • The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3

    Jorge H. Capdevila;Shozou Wei;Christian Helvig;John R. Falck

  • An Active Site Substitution, F87V, Converts Cytochrome P450 BM-3 into a Regio- and Stereoselective (14S,15R)-Arachidonic Acid Epoxygenase

    Sandra Graham-Lorence;Gilles Truan;Julian A. Peterson;John R. Falck

  • Molecular Cloning, Expression and Characterization of an Endogenous Human Cytochrome P450 Arachidonic Acid Epoxygenase Isoform

    Darryl C. Zeldin;Raymond N. DuBois;John R. Falck;Jorge H. Capdevila

  • Functional Variant of CYP4A11 20-Hydroxyeicosatetraenoic Acid Synthase Is Associated With Essential Hypertension

    James V. Gainer;Aouatef Bellamine;Elliott P. Dawson;Kristie E. Womble

  • Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis.

    Jian Kang Chen;Jorge Capdevila;Raymond C. Harris

  • Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids

    Ambra Pozzi;Ines Macias-Perez;Tristin Abair;Shouzuo Wei

  • Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.

    J H Capdevila;S Wei;J Yan;A Karara

  • Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties.

    Armando Karara;Elizabeth Dishman;J R Falck;Jorge H. Capdevila

  • Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase

    J H Capdevila;A Karara;D J Waxman;M V Martin

Frequent Co-Authors

John R. Falck
John R. Falck The University of Texas Southwestern Medical Center
Raymond C. Harris
Raymond C. Harris Vanderbilt University Medical Center
John D. Imig
John D. Imig Medical College of Wisconsin
Michal L. Schwartzman
Michal L. Schwartzman New York Medical College
Ian A. Blair
Ian A. Blair University of Pennsylvania
Michael R. Waterman
Michael R. Waterman Vanderbilt University
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
Wen-Hui Wang
Wen-Hui Wang New York Medical College
Darryl C. Zeldin
Darryl C. Zeldin National Institutes of Health
Nancy J. Brown
Nancy J. Brown Vanderbilt University Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a wide range of rewarding careers in healthcare, research, and education. With the growing demand for flexibility in education, many students are turning to online degree programs to gain the skills needed for these fields.

Advanced studies such as a doctorate in healthcare management can prepare you for leadership roles in hospitals, clinics, and public health organizations. For those interested in clinical pharmacy and medication management, consider exploring the comprehensive online pharmd programs now available.

If your interests lean more toward human movement, physical health, or sports, you may want to look into an online exercise science degree or specialize with online kinesiology programs. These degrees can lead to careers as exercise physiologists, wellness coaches, or rehabilitation specialists.

Online degrees provide the flexibility to study at your own pace while accessing top programs across the country, making them an excellent option for balancing education with other life commitments.

Best Scientists Citing Jorge H. Capdevila

Trending Scientists

Recently Published Articles