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Myung-Shik Lee

Myung-Shik Lee

D-Index & Metrics

Medicine

D-Index
92
Citations
55876
World Ranking
11067
National Ranking
29

Overview

Myung-Shik Lee is affiliated with Yonsei University in South Korea and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Epidemiology, Physiology, Surgery, and Genetics, reflecting a broad scientific focus.

Major research topics include:

  • Autophagy in Disease and Therapy
  • Calcium signaling and nucleotide metabolism
  • Pancreatic function and diabetes
  • Inflammasome and immune disorders
  • GDF15 and Related Biomarkers
  • Liver Disease Diagnosis and Treatment
  • RNA modifications and cancer

Frequent publication venues for their research are:

  • Autophagy
  • Nature Communications
  • Cell Death Discovery
  • Experimental & Molecular Medicine
  • Frontiers in Immunology

Recent papers authored or co-authored by Myung-Shik Lee include:

  • "SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease," 2020, Nature Communications
  • "Identification of type 2 diabetes loci in 433,540 East Asian individuals," 2020, Nature
  • "Mitochondrial event as an ultimate step in ferroptosis," 2022, Cell Death Discovery
  • "TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response," 2021, Nature Metabolism
  • "A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome," 2021, Hepatology

Frequent collaborators in their work include:

  • Soo Jin Oh
  • Jinyoung Kim
  • Kook Hwan Kim
  • Kihyoun Park
  • Kyu Yeon Hur

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice

    Na Ri Shin;June Chul Lee;Hae Youn Lee;Min Soo Kim

  • Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

    Yoshinobu Ichimura;Satoshi Waguri;Yu shin Sou;Shun Kageyama

  • Autophagy--a key player in cellular and body metabolism.

    Kook Hwan Kim;Myung-Shik Lee

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

    Kook Hwan Kim;Yeon Taek Jeong;Hyunhee Oh;Seong Hun Kim

  • Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

    Yoshihiro Inami;Satoshi Waguri;Ayako N. Sakamoto;Tsuguka Kouno

  • Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

    Hye Seung Jung;Kun Wook Chung;Jeong Won Kim;Jin Kim

  • Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice.

    Lise Wogensen;Myung Shik Lee;Nora Sarvetnick

  • p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.

    Tetsuya Saito;Yoshinobu Ichimura;Yoshinobu Ichimura;Keiko Taguchi;Takafumi Suzuki

  • Identification of type 2 diabetes loci in 433,540 East Asian individuals

    Cassandra N Spracklen;Cassandra N Spracklen;Momoko Horikoshi;Young Jin Kim;Kuang Lin

  • Factors affecting graft and patient survival after live donor kidney transplantation in the UK.

    Ki-Soo Park;Young-Seok Kim;Jae-Hyeon Kim;Bongkum Choi

  • SGLT2 Inhibition Modulates NLRP3 Inflammasome Activity via Ketones and Insulin in Diabetes With Cardiovascular Disease

    So Ra Kim;Sang Guk Lee;Soo Hyun Kim;Jin Hee Kim

  • Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

    Giovanni Solinas;Willscott Naugler;Francesco Galimi;Myung Shik Lee

  • STAT1 as a key modulator of cell death.

    Hun Sik Kim;Myung-Shik Lee

  • The emerging role of autophagy in the pathophysiology of diabetes mellitus

    Claudio D. Gonzalez;Myung Shik Lee;Piero Marchetti;Massimo Pietropaolo

  • Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans

    Kook Hwan Kim;Seong Hun Kim;Young-Ki Min;Hun-Mo Yang

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

Frequent Co-Authors

Kyoungho Suk
Kyoungho Suk Kyungpook National University
Nora Sarvetnick
Nora Sarvetnick University of Nebraska Medical Center
Masaaki Komatsu
Masaaki Komatsu Juntendo University
Sergio Lavandero
Sergio Lavandero University of Chile
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Eun-Kyeong Jo
Eun-Kyeong Jo Chungnam National University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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