World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
109
Citations
42550
World Ranking
936
National Ranking
38

Medicine

D-Index
109
Citations
44107
World Ranking
5776
National Ranking
324

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2018 - Member of Academia Europaea

Overview

Ingrid Fleming is affiliated with Goethe University Frankfurt in Germany. Their research primarily intersects the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine, with a total of 92 and 86 publications respectively in these main areas.

The scientist's work further specializes into subfields including Molecular Biology, Biochemistry, Physiology, Immunology, and Cardiology and Cardiovascular Medicine. These subfields have contributed to a wide range of studies across molecular and physiological mechanisms relevant to health and disease.

The main research topics covered by Ingrid Fleming include:

  • Eicosanoids and Hypertension Pharmacology
  • Cancer, Hypoxia, and Metabolism
  • Sulfur Compounds in Biology
  • Immune cells in cancer
  • Nitric Oxide and Endothelin Effects
  • Hormonal Regulation and Hypertension
  • Congenital heart defects research

Frequent venues for publication highlight the scientist's active contributions to both preprint and peer-reviewed journals. These include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cardiovascular Research
  • Cells
  • Nature Communications
  • International Journal of Molecular Sciences

Their collaborative network features multiple recurrent coauthors, demonstrating distinct ongoing research partnerships. Notable frequent coauthors include:

  • Jiong Hu
  • Stefan Günther
  • Ilka Wittig
  • Sofia-Iris Bibli
  • Sven Zukunft

Selected recent publications by Ingrid Fleming provide insight into their research focus and outputs. These include:

  • Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets, 2021, Signal Transduction and Targeted Therapy
  • Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction, 2021, Nature Communications
  • Inhibition of fatty acid oxidation enables heart regeneration in adult mice, 2023, Nature
  • Perivascular adipose tissue as a source of therapeutic targets and clinical biomarkers, 2023, European Heart Journal
  • Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice, 2020, Nature Communications

Ingrid Fleming was recognized with the honor of becoming a Member of Academia Europaea in 2018.

Best Publications

  • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

    Stefanie Dimmeler;Ingrid Fleming;Beate Fisslthaler;Corinna Hermann

  • Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

    Ingrid Fleming;Rudi Busse

  • Cytochrome P450 2C is an EDHF synthase in coronary arteries

    Beate Fisslthaler;Rüdiger Popp;Ladislau Kiss;Michael Potente

  • EDHF: bringing the concepts together.

    Rudi Busse;Gillian Edwards;Michel Félétou;Ingrid Fleming

  • Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

    Ingrid Fleming;Beate Fisslthaler;Stefanie Dimmeler;Bruce E. Kemp

  • Transdifferentiation of Blood-Derived Human Adult Endothelial Progenitor Cells Into Functionally Active Cardiomyocytes

    Cornel Badorff;Ralf P. Brandes;Rüdiger Popp;Stefan Rupp

  • Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets.

    Bei Wang;Lujin Wu;Jing Chen;Lingli Dong

  • Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway.

    G. Julou-Schaeffer;G. A. Gray;I. Fleming;C. Schott

  • Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries

    Ingrid Fleming;U. Ruth Michaelis;Daniel Bredenkötter;Beate Fisslthaler

  • Nitric Oxide Attenuates the Release of Endothelium-Derived Hyperpolarizing Factor

    Johann Bauersachs;Ru¨diger Popp;Markus Hecker;Edith Sauer

  • Molecular mechanisms underlying the activation of eNOS

    Ingrid Fleming

  • Cytochrome P450 and Vascular Homeostasis

    Ingrid Fleming

  • Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium

    Joris Vriens;Grzegorz Owsianik;B Fisslthaler;M Suzuki

  • Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis).

    Dimitri Scholz;Wulf Ito;Ingrid Fleming;Elisabeth Deindl

  • Activation and Signaling by the AMP-Activated Protein Kinase in Endothelial Cells

    Beate Fisslthaler;Ingrid Fleming

  • Endothelial Dysfunction Coincides With an Enhanced Nitric Oxide Synthase Expression and Superoxide Anion Production

    Anne Bouloumié;Johann Bauersachs;Wolfgang Linz;Bernward A. Schölkens

  • Intracellular pH and Tyrosine Phosphorylation but Not Calcium Determine Shear Stress–Induced Nitric Oxide Production in Native Endothelial Cells

    Kazuhide Ayajiki;Markus Kindermann;Markus Hecker;Ingrid Fleming

  • An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice

    Ralf P. Brandes;Friedrich-Hubertus Schmitz-Winnenthal;Michel Félétou;Axel Gödecke

  • Ca2+-Independent Activation of the Endothelial Nitric Oxide Synthase in Response to Tyrosine Phosphatase Inhibitors and Fluid Shear Stress

    Ingrid Fleming;Johann Bauersachs;Beate Fisslthaler;Rudi Busse

  • Endothelial dysfunction in atherosclerosis.

    Rudi Busse;Ingrid Fleming

Frequent Co-Authors

Rudi Busse
Rudi Busse Goethe University Frankfurt
Ralf P. Brandes
Ralf P. Brandes Goethe University Frankfurt
Bruce D. Hammock
Bruce D. Hammock University of California, Davis
Jean-Claude Stoclet
Jean-Claude Stoclet Centre national de la recherche scientifique, CNRS
Ilka Wittig
Ilka Wittig Goethe University Frankfurt
Stefanie Dimmeler
Stefanie Dimmeler Goethe University Frankfurt
Johann Bauersachs
Johann Bauersachs Hannover Medical School
Andreas Papapetropoulos
Andreas Papapetropoulos National and Kapodistrian University of Athens
John R. Falck
John R. Falck The University of Texas Southwestern Medical Center
Andreas M. Zeiher
Andreas M. Zeiher Goethe University Frankfurt

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