Dennis R. Koop

Overview

Best Publications

• Oxidative and reductive metabolism by cytochrome P450 2E1.

  Dennis R. Koop

  797
  Citations

• Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.

  D R Koop;E T Morgan;G E Tarr;M J Coon

  703
  Citations

• Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.

  D R Koop

  503
  Citations

• On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction.

  L D Gorsky;D R Koop;M J Coon

  465
  Citations

• Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages

  Teri L Wadsworth;Dennis R Koop

  423
  Citations

• Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes.

  D R Koop;J P Casazza

  352
  Citations

• Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols.

  E T Morgan;D R Koop;M J Coon

  322
  Citations

• Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes

  Chung S. Yang;Yityoong Y. Tu;Dennis R. Koop;Minor J. Coon

  313
  Citations

• Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid.

  Dennis R. Koop;Becky L. Crump;Gerald D. Nordblom;Minor J. Coon

  299
  Citations

• Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1

  Ronald M. Laethem;Michael Balazy;J R Falck;Carmen L. Laethem

  284
  Citations

• Multiple mechanisms in the regulation of ethanol-inducible cytochrome P450IIE1

  Dennis R. Koop;Daniel J. Tierney

  278
  Citations

• Steatohepatitis induced by intragastric overfeeding in mice

  Qing Gao Deng;Hongyun She;Jason H. Cheng;Samuel W. French;Samuel W. French

  263
  Citations

• Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride— and iron-dependent microsomal lipid peroxidation

  Tirso Castillo;Dennis R. Koop;Seiichiro Kamimura;George Triadafilopoulos

  258
  Citations

• Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.

  B E Daikh;J M Lasker;J L Raucy;D R Koop

  239
  Citations

• CYP2E1 is not involved in early alcohol-induced liver injury

  Hiroshi Kono;Blair U. Bradford;Ming Yin;Kathleen K. Sulik

  227
  Citations

• Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a

  Dene E. Ryan;Dennis R. Koop;Paul E. Thomas;Minor J. Coon

  225
  Citations

• Attenuation of CCl4-induced hepatic fibrosis by GdCl3 treatment or dietary glycine

  C. A. Rivera;B. U. Bradford;K. J. Hunt;Y. Adachi

  216
  Citations

• A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer.

  Joshi J. Alumkal;Rachel Slottke;Jacob Schwartzman;Ganesh Cherala

  216
  Citations

• Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha.

  Teri L Wadsworth;Tasha L McDonald;Dennis R Koop

  209
  Citations

• Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages - Ten years after

  Teri L. Wadsworth;Dennis R. Koop

  0
  Citations