Edward T. Morgan

Overview

Best Publications

• Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.

  D R Koop;E T Morgan;G E Tarr;M J Coon

  703
  Citations

• Regulation of Cytochromes P450 During Inflammation and Infection

  Edward T. Morgan

  610
  Citations

• REGULATION OF DRUG-METABOLIZING ENZYMES AND TRANSPORTERS IN INFLAMMATION

  Alison E. Aitken;Terrilyn A. Richardson;Edward T. Morgan

  531
  Citations

• Regulation of cytochrome p450 by inflammatory mediators: why and how?

  Edward T. Morgan

  529
  Citations

• Impact of Infectious and Inflammatory Disease on Cytochrome P450–Mediated Drug Metabolism and Pharmacokinetics

  Edward T Morgan

  479
  Citations

• Regulation of Drug Metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer

  Edward T. Morgan;Kerry B. Goralski;Micheline Piquette-Miller;Kenneth W. Renton

  436
  Citations

• Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.

  Alison E. Aitken;Edward T. Morgan

  418
  Citations

• Regulation of Drug Metabolizing Enzymes and Transporters in Infection, Inflammation, and Cancer

  Edward T. Morgan;Choon-Myung Lee;Beatrice A. Nyagode

  372
  Citations

• Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat.

  E. T. Morgan;C. MacGeoch;Jan-Ake Gustafsson

  339
  Citations

• Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols.

  E T Morgan;D R Koop;M J Coon

  322
  Citations

• Suppression of constitutive cytochrome P-450 gene expression in livers of rats undergoing an acute phase response to endotoxin.

  E T Morgan

  206
  Citations

• Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen

  Edward T. Morgan;Dennis R. Koop;Minor J. Coon

  200
  Citations

• Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.

  Chi Chen;Yatrik M. Shah;Keiichirou Morimura;Kristopher W. Krausz

  193
  Citations

• Bimodal Regulation of Ceramidase by Interleukin-1β IMPLICATIONS FOR THE REGULATION OF CYTOCHROME P450 2C11 (CYP2C11)

  Mariana Nikolova-Karakashian;Edward T. Morgan;Christopher Alexander;Dennis C. Liotta

  186
  Citations

• Cancer, inflammation, and therapy: effects on cytochrome p450-mediated drug metabolism and implications for novel immunotherapeutic agents.

  R Donald Harvey;E T Morgan

  147
  Citations

• Hepatic cytochrome P450 regulation in disease states.

  Po-Yung Cheng;Edward Morgan

  145
  Citations

• Mechanisms of cytochrome P450 regulation by inflammatory mediators.

  Edward T Morgan;Tong Li-Masters;Po-Yung Cheng

  143
  Citations

• Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5.

  E T Morgan;M J Coon

  138
  Citations

• Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450.

  Marion B. Sewer;Dennis R. Koop;Edward T. Morgan

  138
  Citations

• Suppression of the constitutive expression of cytochrome P-450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6.

  Jin Qiang Chen;Anders Ström;Jan-Ake Gustafsson;Edward T. Morgan

  137
  Citations