What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
Olivier Fardel spends much of his time researching Biochemistry, Cell biology, Multidrug resistance-associated protein 2, Hepatocyte and Efflux.
His Cell biology research includes themes of Arsenic trioxide, Carcinogen, Immune system, Antigen and Macrophage.
The various areas that Olivier Fardel examines in his Multidrug resistance-associated protein 2 study include Receptor, Internal medicine, Endocrinology and Pharmacology.
His Pharmacology research is multidisciplinary, relying on both Multiple drug resistance, Drug resistance, Pregnane X receptor and ATP-binding cassette transporter.
His Hepatocyte study integrates concerns from other disciplines, such as Regulation of gene expression, Oltipraz, Cell culture and In vivo.
His Efflux research includes elements of Proinflammatory cytokine and Organic anion-transporting polypeptide.
His most cited work include:
- Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes. (255 citations)
- Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin. (252 citations)
- Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. (208 citations)
What are the main themes of his work throughout his whole career to date?
Olivier Fardel mainly focuses on Biochemistry, Molecular biology, Cell biology, Pharmacology and Transporter.
His research integrates issues of Arsenic trioxide, P-glycoprotein, Gene expression, Northern blot and Hepatocyte in his study of Molecular biology.
His Cell biology research is multidisciplinary, incorporating elements of Apoptosis, Transcription factor, Immune system and Secretion.
The concepts of his Transporter study are interwoven with issues in Toxicity and Drug.
As a part of the same scientific family, he mostly works in the field of Efflux, focusing on Multiple drug resistance and, on occasion, Immunology.
His work in Multidrug resistance-associated protein 2 addresses subjects such as Internal medicine, which are connected to disciplines such as Gastroenterology.
He most often published in these fields:
- Biochemistry (36.89%)
- Molecular biology (27.18%)
- Cell biology (26.70%)
What were the highlights of his more recent work (between 2017-2021)?
- Transporter (19.90%)
- Drug (8.74%)
- Pharmacology (21.84%)
In recent papers he was focusing on the following fields of study:
Olivier Fardel mostly deals with Transporter, Drug, Pharmacology, Cancer research and Janus kinase.
His study on Transporter is covered under Biochemistry.
When carried out as part of a general Biochemistry research project, his work on Organic anion transporter 1, Carbamate, Carbamate pesticides and Transport protein is frequently linked to work in Agrochemical, therefore connecting diverse disciplines of study.
His work on Drug metabolism as part of general Pharmacology research is often related to Absorption rate, Small sample, Context and Functional features, thus linking different fields of science.
His study in Cancer research is interdisciplinary in nature, drawing from both Jurkat cells, Inflammation, Apoptosis, Efferocytosis and Apoptotic cell clearance.
His Cell biology research incorporates themes from Regulation of gene expression, Pregnane X receptor and Cell type.
Between 2017 and 2021, his most popular works were:
- Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats. (29 citations)
- The JAK1/2 Inhibitor Ruxolitinib Reverses Interleukin-6-Mediated Suppression of Drug-Detoxifying Proteins in Cultured Human Hepatocytes (18 citations)
- Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement. (17 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Olivier Fardel focuses on Cancer research, Janus kinase, Inflammation, STAT protein and Ruxolitinib.
Olivier Fardel has included themes like Tumor necrosis factor alpha, Jurkat cells, CXCL10 and Apoptotic cell clearance in his Cancer research study.
His research in Janus kinase intersects with topics in Pulmonary fibrosis, CCL18 and TLR4.
His work deals with themes such as Phagocytosis, Apoptosis, Macrophage polarization, Efferocytosis and RHOA, which intersect with Inflammation.
His studies deal with areas such as Lipopolysaccharide, Receptor, Signal transduction, Serum amyloid A and Pharmacology as well as Interleukin.
His Cytokine research is multidisciplinary, incorporating perspectives in Proinflammatory cytokine, Interferon, STAT1 and Chemokine.
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