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Olivier Fardel

Olivier Fardel

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
12083
World Ranking
9364
National Ranking
331

Overview

Olivier Fardel is affiliated with the University of Rennes in France and specializes in the field of medicine. Their academic work spans a variety of subfields including oncology, pharmacology, pediatrics, perinatology and child health, health, toxicology and mutagenesis, and molecular biology.

Their research focuses on multiple main topics such as drug transport and resistance mechanisms, pharmacological effects and toxicity studies, pharmacogenetics and drug metabolism, drug-induced hepatotoxicity and protection, antibiotics pharmacokinetics and efficacy, as well as air quality and health impacts and air quality monitoring and forecasting.

Frequent publication venues for Olivier Fardel include:

  • Environmental Pollution
  • European Journal of Drug Metabolism and Pharmacokinetics
  • Xenobiotica
  • Expert Opinion on Drug Metabolism & Toxicology
  • International Journal of Environmental Research and Public Health

Some of the recent papers authored or co-authored by Olivier Fardel are:

  • Combined anti-fibrotic and anti-inflammatory properties of JAK-inhibitors on macrophages in vitro and in vivo: Perspectives for scleroderma-associated interstitial lung disease, 2020, Biochemical Pharmacology
  • Crystalline Silica Impairs Efferocytosis Abilities of Human and Mouse Macrophages: Implication for Silica-Associated Systemic Sclerosis, 2020, Frontiers in Immunology
  • Determination of glyphosate and AMPA in indoor settled dust by hydrophilic interaction liquid chromatography with tandem mass spectrometry and implications for human exposure, 2022, Journal of Hazardous Materials
  • Interactions of janus kinase inhibitors with drug transporters and consequences for pharmacokinetics and toxicity, 2020, Expert Opinion on Drug Metabolism & Toxicology
  • Nitrogen Dioxide Inhalation Exposures Induce Cardiac Mitochondrial Reactive Oxygen Species Production, Impair Mitochondrial Function and Promote Coronary Endothelial Dysfunction, 2020, International Journal of Environmental Research and Public Health

Olivier Fardel has collaborated frequently with several co-authors, including:

  • Marc Le Vée
  • Arnaud Bruyère
  • Elodie Jouan
  • Valérie Lecureur
  • Jennifer Carteret

Best Publications

  • Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin.

    Marie Jaguin;Noémie Houlbert;Olivier Fardel;Valérie Lecureur

  • Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes.

    Emilie Jigorel;Marc Le Vee;Claire Boursier-Neyret;Yannick Parmentier

  • Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6.

    Marc Le Vee;Valérie Lecureur;Bruno Stieger;Olivier Fardel

  • The P-glycoprotein multidrug transporter.

    Olivier Fardel;Valérie Lecureur;André Guillouzo

  • Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications.

    JE Goasguen;JM Dossot;O Fardel;F Le Mee

  • Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line

    Marc Le Vee;Emilie Jigorel;Denise Glaise;Philippe Gripon

  • Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor.

    Anthony Lemarié;Dominique Lagadic-Gossmann;Claudie Morzadec;Nathalie Allain

  • CD3-CD56+ non-Hodgkin's lymphomas with an aggressive behavior related to multidrug resistance

    Bernard Drénou;Thierry Lamy;Laurence Amiot;Olivier Fardel

  • Polycyclic Aromatic Hydrocarbons Inhibit Differentiation of Human Monocytes into Macrophages

    Julien van Grevenynghe;Sophie Rion;Eric Le Ferrec;Marc Le Vee

  • Analysis of drug transporter expression in human intestinal Caco-2 cells by real-time PCR

    Nathalie Maubon;Marc Le Vee;Lina Fossati;Mathilde Audry

  • Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta

    Marc Le Vee;Philippe Gripon;Bruno Stieger;Olivier Fardel

  • Use of human hepatocyte cultures for drug metabolism studies.

    André Guillouzo;Fabrice Morel;Olivier Fardel;Bernard Meunier

  • Human macrophages constitute targets for immunotoxic inorganic arsenic.

    Anthony Lemarie;Claudie Morzadec;Emilie Bourdonnay;Olivier Fardel

  • Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation.

    Normand Podechard;Valérie Lecureur;Eric Le Ferrec;Isabelle Guenon

  • Preferential Increase of Glutathione S-Transferase Class α Transcripts in Cultured Human Hepatocytes by Phenobarbital, 3-Methylcholanthrene, and Dithiolethiones

    Fabrice Morel;Olivier Fardel;David J. Meyer;Sophie Langouet

  • FUNCTIONAL EXPRESSION OF SINUSOIDAL DRUG TRANSPORTERS IN PRIMARY HUMAN AND RAT HEPATOCYTES

    Emilie Jigorel;Marc Le Vee;Claire Boursier-Neyret;Marc Bertrand

  • Evaluation of P-Glycoprotein Inhibitory Potential Using a Rhodamine 123 Accumulation Assay.

    Elodie Jouan;Marc Le Vée;Abdullah Mayati;Claire Denizot

  • Polycyclic Aromatic Hydrocarbons Affect Functional Differentiation and Maturation of Human Monocyte-Derived Dendritic Cells

    Béatrice Laupeze;Laurence Amiot;Lydie Sparfel;Eric Le Ferrec

  • Up‐regulation of multidrug resistance‐associated protein 2 (MRP2) expression in rat hepatocytes by dexamethasone

    Arnaud Courtois;Léa Payen;André Guillouzo;Olivier Fardel

  • Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene.

    Monique N'Diaye;Eric Le Ferrec;Dominique Lagadic-Gossmann;Sébastien Corre

Frequent Co-Authors

André Guillouzo
André Guillouzo University of Rennes
Renée Fauchet
Renée Fauchet University of Rennes
Bruno Stieger
Bruno Stieger University of Zurich
Christiane Guguen-Guillouzo
Christiane Guguen-Guillouzo University of Rennes
Jørn A. Holme
Jørn A. Holme Norwegian Institute of Public Health
Patrick Balaguer
Patrick Balaguer University of Montpellier
Thierry Douki
Thierry Douki Grenoble Alpes University
Roméo Cecchelli
Roméo Cecchelli Artois University
Olivier Micheau
Olivier Micheau University of Burgundy
Elisabeth G.E. de Vries
Elisabeth G.E. de Vries University Medical Center Groningen

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