D-Index & Metrics Best Publications
Christiane Guguen-Guillouzo

Christiane Guguen-Guillouzo

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 66 Citations 15,595 206 World Ranking 5554 National Ranking 164

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Christiane Guguen-Guillouzo mainly focuses on Cell culture, Cell biology, Molecular biology, Cellular differentiation and Biochemistry. Christiane Guguen-Guillouzo combines subjects such as Drug metabolism and In vitro, Hepatocyte with her study of Cell culture. Her work deals with themes such as Cell, Epidermal growth factor and In vivo, which intersect with Cell biology.

The concepts of her Molecular biology study are interwoven with issues in Virus, Hepatitis B virus, Apoptosis and Transfection. Her research integrates issues of Infectivity and Mutant in her study of Hepatitis B virus. As part of the same scientific family, Christiane Guguen-Guillouzo usually focuses on Cellular differentiation, concentrating on CYP3A4 and intersecting with Pharmacology, Toxicity and Steatosis.

Her most cited work include:

  • Infection of a human hepatoma cell line by hepatitis B virus (901 citations)
  • Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells (495 citations)
  • Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. (472 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of study are Molecular biology, Cell biology, Hepatocyte, Cell culture and Biochemistry. Her biological study spans a wide range of topics, including Gene expression, Cell growth, Virology, Cell cycle and Hepatitis B virus. The study incorporates disciplines such as Cell and Epidermal growth factor in addition to Cell biology.

Her research in Hepatocyte intersects with topics in In vivo, Internal medicine and Endocrinology. The Cell culture study combines topics in areas such as Secretion, Intracellular, Cellular differentiation and Drug metabolism. Her study looks at the relationship between Biochemistry and fields such as Cholestasis, as well as how they intersect with chemical problems.

She most often published in these fields:

  • Molecular biology (33.48%)
  • Cell biology (31.28%)
  • Hepatocyte (28.19%)

What were the highlights of her more recent work (between 2010-2020)?

  • Biochemistry (28.19%)
  • Cholestasis (12.33%)
  • Pharmacology (9.69%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Biochemistry, Cholestasis, Pharmacology, Cell biology and Cell culture. Her research links Bone canaliculus with Biochemistry. Her Cholestasis research is multidisciplinary, incorporating perspectives in Lithocholic acid, Bile acid and Sulfation.

Her Pharmacology study integrates concerns from other disciplines, such as Proinflammatory cytokine, Sitaxentan, Taurocholic acid and Cytotoxicity. The various areas that she examines in her Cell biology study include Transplantation and Heparg cell. Her Cell culture research includes elements of In vitro, Cellular differentiation, Hepatic stellate cell, Drug metabolism and Toxicity.

Between 2010 and 2020, her most popular works were:

  • Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture (238 citations)
  • Optimization of the HepaRG cell model for drug metabolism and toxicity studies (111 citations)
  • Optimization of the HepaRG cell model for drug metabolism and toxicity studies (111 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Biochemistry, Pharmacology, Efflux, Bile acid and Cholestasis are her primary areas of study. Her work on Biochemistry is being expanded to include thematically relevant topics such as Cell culture. Her studies deal with areas such as Cell biology, Bioinformatics and Hepatocyte differentiation as well as Cell culture.

She has included themes like Toxicity, Steatosis, In vitro and Cellular differentiation in her Pharmacology study. Her work carried out in the field of Efflux brings together such families of science as Oxidative stress and Reactive oxygen species. The Bile acid study combines topics in areas such as Phosphorylation and Rho-associated protein kinase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Infection of a human hepatoma cell line by hepatitis B virus

Philippe Gripon;Sylvie Rumin;Stephan Urban;Jacques Le Seyec.
Proceedings of the National Academy of Sciences of the United States of America (2002)

1328 Citations

Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells

Caroline Aninat;Amélie Piton;Denise Glaise;Typhen Le Charpentier.
Drug Metabolism and Disposition (2006)

649 Citations

Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type.

Christiane Guguen-Guillouzo;Bruno Clément;Georges Baffet;Carole Beaumont.
Experimental Cell Research (1983)

613 Citations

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.

André Guillouzo;Anne Corlu;Caroline Aninat;Denise Glaise.
Chemico-Biological Interactions (2007)

582 Citations

Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture

Madhushree Bhattacharya;Melina M. Malinen;Patrick Lauren;Yan-Rou Lou.
Journal of Controlled Release (2012)

419 Citations

Transdifferentiation of hepatocyte‐like cells from the human hepatoma HepaRG cell line through bipotent progenitor

Virginie Cerec;Denise Glaise;Denise Glaise;Delphine Garnier;Delphine Garnier;Serban Morosan;Serban Morosan;Serban Morosan.
Hepatology (2007)

392 Citations

The Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G1 Phase Progression in Proliferating Hepatocytes

Hélène Talarmin;Claude Rescan;Sandrine Cariou;Denise Glaise.
Molecular and Cellular Biology (1999)

364 Citations

C/EBPα Regulates Hepatic Transcription of Hepcidin, an Antimicrobial Peptide and Regulator of Iron Metabolism: CROSS-TALK BETWEEN C/EBP PATHWAY AND IRON METABOLISM

Brice Courselaud;Christelle Pigeon;Yusuke Inoue;Junko Inoue.
Journal of Biological Chemistry (2002)

332 Citations

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1.

Pascal Loyer;Sandrine Cariou;Denise Glaise;Marc Bilodeau.
Journal of Biological Chemistry (1996)

318 Citations

Hepatitis B virus infection of adult human hepatocytes cultured in the presence of dimethyl sulfoxide.

P Gripon;C Diot;N Thézé;I Fourel.
Journal of Virology (1988)

317 Citations

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