D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 9,753 108 World Ranking 12059 National Ranking 953

Overview

What is he best known for?

The fields of study he is best known for:

  • Biochemistry
  • Amino acid
  • Metabolism

Harinder S. Hundal mainly investigates Biochemistry, Internal medicine, Endocrinology, Akt/PKB signaling pathway and Glycogen synthase. The study incorporates disciplines such as Function and Cell biology in addition to Biochemistry. His study connects Protein kinase A and Internal medicine.

Harinder S. Hundal interconnects GSK-3 and ASK1 in the investigation of issues within Akt/PKB signaling pathway. In his study, Myocyte is strongly linked to Glucose uptake, which falls under the umbrella field of Glucose transporter. His biological study spans a wide range of topics, including Effector, Intracellular and Amino acid transporter.

His most cited work include:

  • The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf (444 citations)
  • Amino acid transporters: roles in amino acid sensing and signalling in animal cells (280 citations)
  • Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism (267 citations)

What are the main themes of his work throughout his whole career to date?

Harinder S. Hundal spends much of his time researching Endocrinology, Internal medicine, Biochemistry, Skeletal muscle and Cell biology. His work carried out in the field of Endocrinology brings together such families of science as Protein kinase B and Wortmannin. Harinder S. Hundal works mostly in the field of Protein kinase B, limiting it down to topics relating to Protein kinase C and, in certain cases, IRS1, as a part of the same area of interest.

His Internal medicine research incorporates elements of Diabetes mellitus and Protein kinase A. His Skeletal muscle research is multidisciplinary, incorporating elements of Glucose transporter, Myocyte and GLUT5. His study looks at the intersection of MAP kinase kinase kinase and topics like Akt/PKB signaling pathway with GSK-3.

He most often published in these fields:

  • Endocrinology (43.52%)
  • Internal medicine (43.52%)
  • Biochemistry (39.81%)

What were the highlights of his more recent work (between 2011-2020)?

  • Internal medicine (43.52%)
  • Endocrinology (43.52%)
  • Cell biology (27.78%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Endocrinology, Cell biology, Skeletal muscle and Insulin resistance. In his study, which falls under the umbrella issue of Internal medicine, Obesity is strongly linked to Diabetes mellitus. His research ties Biochemistry and Cell biology together.

His Skeletal muscle research is multidisciplinary, incorporating perspectives in Myocyte and Polyunsaturated fatty acid. His Insulin resistance study is associated with Insulin. His research in Insulin intersects with topics in Protein kinase B and Energy homeostasis.

Between 2011 and 2020, his most popular works were:

  • Defining the Contribution of AMP-activated Protein Kinase (AMPK) and Protein Kinase C (PKC) in Regulation of Glucose Uptake by Metformin in Skeletal Muscle Cells (74 citations)
  • Lipid modulation of skeletal muscle mass and function. (62 citations)
  • Modulation of cellular redox homeostasis by the endocannabinoid system (39 citations)

In his most recent research, the most cited papers focused on:

  • Biochemistry
  • Amino acid
  • Metabolism

The scientist’s investigation covers issues in Biochemistry, Cell biology, Signal transduction, Skeletal muscle and Phosphorylation. His study in the fields of Unsaturated fatty acid, Amino acid and Linoleic acid under the domain of Biochemistry overlaps with other disciplines such as Cellular stress response. His research integrates issues of Glucose transporter and Insulin resistance in his study of Cell biology.

Internal medicine and Endocrinology are the two main areas of interest in his Skeletal muscle studies. His Internal medicine research integrates issues from AMP-activated protein kinase, AMPK and Protein kinase A. Harinder S. Hundal has included themes like Atrophy, Function and Ageing in his Endocrinology study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf

D A E Cross;D R Alessi;J R Vandenheede;H E McDowell.
Biochemical Journal (1994)

688 Citations

Ceramide Disables 3-Phosphoinositide Binding to the Pleckstrin Homology Domain of Protein Kinase B (PKB)/Akt by a PKCζ-Dependent Mechanism

Darren J. Powell;Eric Hajduch;Gursant Kular;Harinder S. Hundal.
Molecular and Cellular Biology (2003)

387 Citations

Amino acid transporters: roles in amino acid sensing and signalling in animal cells

Russell Hyde;Peter M. Taylor;Harinder S. Hundal.
Biochemical Journal (2003)

384 Citations

Protein kinase B (PKB/Akt) – a key regulator of glucose transport?

Eric Hajduch;Gary J Litherland;Harinder S Hundal.
FEBS Letters (2001)

371 Citations

Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells.

H S Hundal;T Ramlal;R Reyes;L A Leiter.
Endocrinology (1992)

322 Citations

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling.

Harinder Singh Hundal;Peter Maving Taylor.
American Journal of Physiology-endocrinology and Metabolism (2009)

319 Citations

Intracellular ceramide synthesis and protein kinase Cζ activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

Darren J. Powell;Sophie Turban;Alexander Gray;Eric Hajduch.
Biochemical Journal (2004)

307 Citations

Insulin induces translocation of the alpha 2 and beta 1 subunits of the Na+/K(+)-ATPase from intracellular compartments to the plasma membrane in mammalian skeletal muscle.

H.S. Hundal;A Marette;Y Mitsumoto;T Ramlal.
Journal of Biological Chemistry (1992)

306 Citations

L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport.

Karine Peyrollier;Eric Hajduch;Anne S. Blair;Russell Hyde.
Biochemical Journal (2000)

290 Citations

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

E. Hajduch;A. Balendran;I. H. Batty;G. J. Litherland.
Diabetologia (2001)

273 Citations

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