World's Best Scientists 2026 revealed!
Laurie J. Goodyear

Laurie J. Goodyear

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
115
Citations
49981
World Ranking
717
National Ranking
435

Medicine

D-Index
118
Citations
52187
World Ranking
4054
National Ranking
2220

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Laurie J. Goodyear is affiliated with Harvard University in the United States and has made significant contributions to the field of Medicine, with a strong focus on Physiology and related subfields. Their research extends across various topics including Adipose Tissue and Metabolism, Exercise and Physiological Responses, and Birth, Development, and Health.

Their frequent coauthors include Pasquale Nigro, Roeland J.W. Middelbeek, Michael F. Hirshman, and Maria Vamvini. These collaborations have contributed to the breadth and depth of Goodyear's work in metabolic studies and physiological processes.

Goodyear's publications are concentrated in several key scientific venues, most notably:

  • Diabetes
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Metabolism
  • Cell Metabolism
  • Molecular Metabolism

Recent notable papers by Laurie J. Goodyear include:

  • Temporal dynamics of the multi-omic response to endurance exercise training (2024, Nature)
  • Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells (2022, Cell Metabolism)
  • Effects of maternal and paternal exercise on offspring metabolism (2020, Nature Metabolism)
  • FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis (2020, Nature Communications)
  • Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation (2022, Nature Metabolism)

Their research topics encompass several areas within medicine, including:

  • Adipose Tissue and Metabolism
  • Exercise and Physiological Responses
  • Birth, Development, and Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Muscle metabolism and nutrition
  • Pregnancy and preeclampsia studies
  • Gestational Diabetes Research and Management

In terms of subfields, Laurie J. Goodyear's work is predominantly placed within:

  • Physiology
  • Rehabilitation
  • Pediatrics, Perinatology and Child Health
  • Molecular Biology
  • Epidemiology

Best Publications

  • Role of AMP-activated protein kinase in mechanism of metformin action

    Gaochao Zhou;Robert Myers;Ying Li;Yuli Chen

  • Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade.

    Margaret E. Griffin;Melissa J. Marcucci;Gary W. Cline;Kim Bell

  • Exercise, glucose transport, and insulin sensitivity.

    Laurie J. Goodyear;Barbara B. Kahn

  • A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

    Jens C Brüning;M.Dodson Michael;Jonathon N Winnay;Tatsuya Hayashi

  • Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

    Kristin I. Stanford;Roeland J.W. Middelbeek;Kristy L. Townsend;Ding An

  • Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport

    Tatsuya Hayashi;Michael F Hirshman;Emily J Kurth;William W Winder

  • Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.

    Nicolas Musi;Michael F. Hirshman;Jonas Nygren;Monika Svanfeldt

  • 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

    E J Kurth-Kraczek;M F Hirshman;L J Goodyear;W W Winder

  • Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

    Zisman A;Peroni Od;Abel Ed;Michael

  • Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

    M Sinha;Y. C. Jang;Y. C. Jang;Juhyun Oh;Juhyun Oh;Danika Mei Po Khong;Danika Mei Po Khong

  • Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.

    L J Goodyear;F Giorgino;L A Sherman;J Carey

  • Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism.

    T Hayashi;M F Hirshman;N Fujii;S A Habinowski

  • Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles.

    Massimiliano Cerletti;Sara Jurga;Sara Jurga;Carol A. Witczak;Michael F. Hirshman

  • Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

    Orsolya M. Palacios;Juan J. Carmona;Shaday Michan;Ke Yun Chen

  • Acute exercise induces GLUT4 translocation in skeletal muscle of normal human subjects and subjects with type 2 diabetes.

    J W Kennedy;M F Hirshman;E V Gervino;J V Ocel

  • Exercise regulation of glucose transport in skeletal muscle

    Tatsuya Hayashi;Jørgen F. P. Wojtaszewski;Laurie J. Goodyear

  • Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

    Andrew W. Norris;Lihong Chen;Simon J. Fisher;Ildiko Szanto

  • Exercise, MAPK, and NF-κB signaling in skeletal muscle

    Henning F. Kramer;Laurie J. Goodyear

  • AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise

    Nicolas Musi;Nobuharu Fujii;Michael F. Hirshman;Ingvar Ekberg

  • Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.

    Nobuharu Fujii;Tatsuya Hayashi;Michael F. Hirshman;Jeremy T. Smith

Frequent Co-Authors

Michael F. Hirshman
Michael F. Hirshman Harvard University
Edward S. Horton
Edward S. Horton Harvard Medical School
Jørgen F. P. Wojtaszewski
Jørgen F. P. Wojtaszewski University of Copenhagen
C. Ronald Kahn
C. Ronald Kahn Harvard University
Yu-Hua Tseng
Yu-Hua Tseng Harvard University
Kei Sakamoto
Kei Sakamoto University of Copenhagen
Roger A. Fielding
Roger A. Fielding Tufts University
Erik A. Richter
Erik A. Richter University of Copenhagen
Mary-Elizabeth Patti
Mary-Elizabeth Patti Harvard University
Olle Ljungqvist
Olle Ljungqvist Örebro University

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