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Bernard Jégou

Bernard Jégou

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
19279
World Ranking
4606
National Ranking
118

Overview

Bernard Jégou was a researcher primarily affiliated with Inserm in France. Their academic work focused extensively on medicine and biochemistry, genetics, and molecular biology, with significant contributions spanning various subfields such as molecular biology, public health, environmental and occupational health, pharmacology, pediatrics, perinatology, child health, and epidemiology.

The research topics explored by Bernard Jégou included pharmacological effects and toxicity studies, metabolomics and mass spectrometry studies, pregnancy and medication impact, sexual differentiation and disorders, drug-induced hepatotoxicity and protection, pharmacogenetics and drug metabolism, as well as health, environment, and cognitive aging.

Bernard Jégou authored multiple papers that appeared in well-recognized scientific venues. Notable recent publications included:

  • Paracetamol use during pregnancy - a call for precautionary action, 2021, Nature Reviews Endocrinology
  • Spatiotemporal trends in human semen quality, 2022, Nature Reviews Urology
  • Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis, 2020, Human Reproduction
  • Dynamics of the transcriptional landscape during human fetal testis and ovary development, 2020, Human Reproduction
  • Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring, 2021, Environment International

The frequent co-authors who collaborated on their research included Antoine D. Rolland, David M. Kristensen, Frédéric Chalmel, Arthur David, and Jade Chaker.

Bernard Jégou contributed to the academic literature through publications in several key venues:

  • Human Reproduction
  • Environment International
  • Analytical Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Reviews Endocrinology

Best Publications

  • Male reproductive health and environmental xenoestrogens

    J Toppari;JC Larsen;P Christiansen;A Giwercman

  • Antioxidant system in rat testicular cells

    Françoise Bauché;Marie Hélène Fouchard;Bernard Jégou

  • Viruses in the mammalian male genital tract and their effects on the reproductive system.

    Nathalie Dejucq;Bernard Jégou

  • Chlordecone Exposure and Risk of Prostate Cancer

    Luc Multigner;Jean Rodrigue Ndong;Arnaud Giusti;Marc Romana

  • Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

    David Møbjerg Boslev Kristensen;Ulla Hass;Laurianne Lesné;Grete Lottrup

  • Induction of CREM activator proteins in spermatids: down-stream targets and implications for haploid germ cell differentiation.

    V Delmas;F van der Hoorn;B Mellström;B Jégou

  • Expression of Antimicrobial Defensins in the Male Reproductive Tract of Rats, Mice, and Humans

    Emmanuelle Com;Frédéric Bourgeon;Bertrand Evrard;Tomas Ganz

  • The conserved transcriptome in human and rodent male gametogenesis.

    Frédéric Chalmel;Antoine D. Rolland;Christa Niederhauser-Wiederkehr;Sanny S. W. Chung

  • An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.

    Jean-Luc Pitetti;Pierre Calvel;Céline Zimmermann;Béatrice Conne

  • MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells

    Aminata Touré;Olivier Dorseuil;Laurence Morin;Paula Timmons

  • Human testis steroidogenesis is inhibited by phthalates.

    C. Desdoits-Lethimonier;O. Albert;O. Albert;B. Le Bizec;E. Perdu

  • Sertoli cell Dicer is essential for spermatogenesis in mice.

    Marilena D. Papaioannou;Jean-Luc Pitetti;Seungil Ro;Chanjae Park

  • Bcl-w Forms Complexes with Bax and Bak, and Elevated Ratios of Bax/Bcl-w and Bak/Bcl-w Correspond to Spermatogonial and Spermatocyte Apoptosis in the Testis

    Wei Yan;Michel Samson;Bernard Jégou;Jorma Toppari

  • Human Leydig cells and Sertoli cells are producers of interleukins-1 and -6.

    Corinne Cudicini;Corinne Cudicini;Hervé Lejeune;Edith Gomez;Eugène Bosmans

  • Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate.

    Chris McKinnell;Richard M. Sharpe;Kim Mahood;Nina Hallmark

  • Paracetamol, aspirin and indomethacin display endocrine disrupting properties in the adult human testis in vitro

    Océane Albert;Océane Albert;Christele Desdoits-Lethimonier;Christele Desdoits-Lethimonier;Laurianne Lesné;Laurianne Lesné;Alain Legrand;Alain Legrand

  • Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.

    Séverine Mazaud-Guittot;Christophe Nicolas Nicolaz;Christèle Desdoits-Lethimonier;Isabelle Coiffec

  • Involvement of Bcl-2 family proteins in germ cell apoptosis during testicular development in the rat and pro-survival effect of stem cell factor on germ cells in vitro.

    Wei Yan;Janne Suominen;Michel Samson;Bernard Jégou

  • Analgesic use — prevalence, biomonitoring and endocrine and reproductive effects

    David Møbjerg Kristensen;Sverine Mazaud-Guittot;Pierre Gaudriault;Laurianne Lesne

  • Multidrug Resistance Genes and P-Glycoprotein in the Testis of the Rat, Mouse, Guinea Pig, and Human

    Nathalie Melaine;Marie-Odile Liénard;Isabelle Dorval;Claude Le Goascogne

Frequent Co-Authors

Michel Samson
Michel Samson University of Rennes
Jorma Toppari
Jorma Toppari University of Turku
Richard M. Sharpe
Richard M. Sharpe University of Edinburgh
Tina Kold Jensen
Tina Kold Jensen University of Southern Denmark
Ewa Rajpert-De Meyts
Ewa Rajpert-De Meyts University of Copenhagen
Jean-Philippe Antignac
Jean-Philippe Antignac INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Søren Brunak
Søren Brunak University of Copenhagen
Christiane Guguen-Guillouzo
Christiane Guguen-Guillouzo University of Rennes
Henrik Leffers
Henrik Leffers Copenhagen University Hospital
Anders Hay-Schmidt
Anders Hay-Schmidt University of Copenhagen

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