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Biology and Biochemistry

D-Index
71
Citations
19094
World Ranking
6601
National Ranking
58

Overview

Henrik Leffers is affiliated with Copenhagen University Hospital in Denmark. Their research primarily focuses on systemic lupus erythematosus (SLE), with significant attention to comorbidities and clinical phenotypes related to autoimmune and cardiovascular conditions.

The scientist's main field of study is medicine, with a concentration in rheumatology. Subfields also include immunology, pathology and forensic medicine, cardiology and cardiovascular medicine, and epidemiology.

Topics addressed in their work cover a range of areas such as systemic lupus erythematosus research, systemic sclerosis and related diseases, atherosclerosis and cardiovascular diseases, rheumatoid arthritis research and therapies, heart rate variability and autonomic control, stress responses and cortisol, and cytokine signaling pathways and interactions.

Frequent venues for publication include:

  • Annals of the Rheumatic Diseases
  • Poster presentations
  • Lupus Science & Medicine
  • Clinical and Experimental Rheumatology
  • Joint Bone Spine

Selected recent papers authored or coauthored by Henrik Leffers are:

  • Smoking associates with distinct clinical phenotypes in patients with systemic lupus erythematosus: a nationwide Danish cross-sectional study, 2021, Lupus Science & Medicine
  • Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: A Danish genome-wide association study, 2022, Joint Bone Spine

Other notable papers include:

  • Characteristics of cardiovascular autonomic dysfunction and association with quality of life in patients with systemic lupus erythematosus, 2021, Lupus Science & Medicine
  • Patient-reported outcome measures in systemic lupus erythematosus by a web-based application: A randomized, crossover, agreement study, 2021, Lupus
  • POS0484 THE NATIONWIDE DANISH DANBIO REGISTRY FOR PATIENT CARE AND DECISION SUPPORT: IMPROVED MONITORING IN >25.000 PATIENTS WITH RHEUMATOID ARTHRITIS, 2024, Annals of the Rheumatic Diseases

Henrik Leffers collaborates frequently with several researchers, including:

  • Søren Jacobsen
  • Lene Dreyer
  • Anne Troldborg
  • Anne Voss
  • Salome Kristensen

Best Publications

  • Male reproductive health and environmental xenoestrogens

    J Toppari;JC Larsen;P Christiansen;A Giwercman

  • The structural basis for 14-3-3:phosphopeptide binding specificity.

    Michael B Yaffe;Katrin Rittinger;Stefano Volinia;Paul R Caron

  • Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals.

    Helle Raun Andersen;Anna-Maria Andersson;Steven F. Arnold;Herman Autrup

  • Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin.

    Peder Madsen;Hanne H Rasmussen;Henrik Leffers;Bent Honoré

  • Do perfluoroalkyl compounds impair human semen quality

    Ulla Nordström Joensen;Rossana Bossi;Henrik Leffers;Allan Astrup Jensen

  • Emerging endocrine disrupters: perfluoroalkylated substances

    Allan Astrup Jensen;Henrik Leffers

  • Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract

    Martin Blomberg Jensen;John E Nielsen;Anne Jørgensen;Ewa Rajpert-De Meyts

  • Is human fecundity declining

    Niels E Skakkebaek;Niels Jørgensen;Katharina M Main;Ewa Rajpert-De Meyts

  • Molecular Cloning and Expression of a Novel Keratinocyte Protein (Psoriasis-associated fatty acid-binding protein [PA-FABP]) that Is Highly Up-Regulated in Psoriatic Skin and that Shares Similarity to Fatty Acid-Binding Proteins

    Peder. Madsen;Hanne H Rasmussen;Henrik. Leffers;Bent. Honoré

  • Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat

    David Møbjerg Boslev Kristensen;Ulla Hass;Laurianne Lesné;Grete Lottrup

  • Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome

    Gabriela Puhler;Henrik Leffers;Felix Gropp;Peter Palm

  • Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.

    Kristian Almstrup;Christina E. Hoei-Hansen;Ute Wirkner;Jonathon Blake

  • Characterisation of Two Major Cellular Poly(rC)-Binding Human Proteins, Each Containing Three K-homologous (KH) Domains

    Henrik Leffers;Kurt Dejgaard;Julio E. Celis

  • Molecular Cloning and Expression of the Transformation Sensitive Epithelial Marker Stratifin: A Member of a Protein Family that has been Involved in the Protein Kinase C Signalling Pathway

    Henrik Leffers;Peder Madsen;Hanne H. Rasmussen;Bent Honore

  • Possible impact of phthalates on infant reproductive health.

    G. Lottrup;A.‐M. Andersson;H. Leffers;G. K. Mortensen

  • Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours.

    C E Hoei-Hansen;K Almstrup;J E Nielsen;S Brask Sonne

  • Determination of phthalate monoesters in human milk, consumer milk, and infant formula by tandem mass spectrometry (LC-MS-MS).

    Gerda K. Mortensen;Katharina M. Main;Anna-Maria Andersson;Henrik Leffers

  • Evolutionary relationships amongst archaebacteria. A comparative study of 23 S ribosomal RNAs of a sulphur-dependent extreme thermophile, an extreme halophile and a thermophilic methanogen.

    Henrik Leffers;Jørgen Kjems;Laust Østergaard;Niels Larsen

  • Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.

    Christina E. Hoei-Hansen;John E. Nielsen;Kristian Almstrup;Si Brask Sonne

  • Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of puberty

    A. Mouritsen;L. Aksglaede;K. Sørensen;S. Sloth Mogensen

Frequent Co-Authors

Niels E. Skakkebæk
Niels E. Skakkebæk University of Copenhagen
Ewa Rajpert-De Meyts
Ewa Rajpert-De Meyts University of Copenhagen
Bent Honoré
Bent Honoré Aarhus University
Peder Madsen
Peder Madsen Aarhus University
Julio E. Celis
Julio E. Celis Breast Cancer Research Foundation
Anders Juul
Anders Juul University of Copenhagen
Søren Brunak
Søren Brunak University of Copenhagen
Joël Vandekerckhove
Joël Vandekerckhove Ghent University
Niels Jørgensen
Niels Jørgensen University of Copenhagen
Jørgen Holm Petersen
Jørgen Holm Petersen University of Copenhagen

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