World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
76
Citations
21288
World Ranking
1151
National Ranking
90

Research.com Recognitions

  • 2002 - Fellow of the Royal Society of Edinburgh
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

J. Julian Blow is affiliated with the University of Dundee in the United Kingdom, where their research primarily focuses on biochemistry, genetics, and molecular biology. Their work spans areas such as molecular biology, cell biology, hematology, genetics, and plant science, with a particular emphasis on DNA repair mechanisms and genomics.

The scientist's recent publications highlight contributions to protein degradation and inhibitors, as well as chromatin dynamics and genome replication. Notable papers include:

  • Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins (2021, Journal of Medicinal Chemistry)
  • The role of DDK and Treslin-MTBP in coordinating replication licensing and pre-initiation complex formation (2021, Open Biology)
  • DDK: The Outsourced Kinase of Chromosome Maintenance (2022, Biology)
  • The location and development of Replicon Cluster Domains in early replicating DNA (2023, Wellcome Open Research)

J. Julian Blow frequently collaborates with several researchers, including:

  • Peter J. Gillespie
  • Adam G. Bond
  • Conner Craigon
  • Kwok-Ho Chan
  • Andrea Testa

The scientist publishes regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Medicinal Chemistry, Wellcome Open Research, Nature Communications, and Open Biology.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • Wellcome Open Research
  • Nature Communications
  • Open Biology

Research interests and topics addressed by J. Julian Blow encompass:

  • DNA Repair Mechanisms
  • Genomics and Chromatin Dynamics
  • Microtubule and mitosis dynamics
  • Protein Degradation and Inhibitors
  • Multiple Myeloma Research and Treatments
  • Bacterial Genetics and Biotechnology
  • RNA Research and Splicing

J. Julian Blow has been recognized with several awards and honors, including:

  • Fellow of the Royal Society of Edinburgh (2002)
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5

    Laurent Meijer;Annie Borgne;Odile Mulner;James P.J. Chong

  • Preventing re-replication of chromosomal DNA

    J. Julian Blow;Anindya Dutta

  • A role for the nuclear envelope in controlling DNA replication within the cell cycle.

    J. Julian Blow;Ronald A. Laskey

  • Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs.

    J.Julian Blow;Ronald A. Laskey

  • Dormant origins licensed by excess Mcm2–7 are required for human cells to survive replicative stress

    Xin Quan Ge;Dean A. Jackson;J. Julian Blow

  • Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

    C Norbury;J Blow;P Nurse

  • Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

    Shusuke Tada;Anatoliy Li;Domenico Maiorano;Marcel Méchali

  • Translation of Cyclin mRNA Is Necessary for Extracts of Activated Xenopus Eggs to Enter Mitosis

    Jeremy Minshull;J.Julian Blow;Tim Hunt

  • Purification of an MCM-containing complex as a component of the DNA replication licensing system

    James P. J. Chong;Hiro M. Mahbubani;Chong-Yee Khoo;J. Julian Blow

  • Excess Mcm2–7 license dormant origins of replication that can be used under conditions of replicative stress

    Anna M. Woodward;Thomas Göhler;M. Gloria Luciani;Maren Oehlmann

  • S phase of the cell cycle

    Ronald A. Laskey;Micaela P. Fairman;J. Julian Blow

  • Replication licensing — Origin licensing: defining the proliferative state?

    J.Julian Blow;Ben Hodgson

  • Interaction between the origin recognition complex and the replication licensing system in Xenopus.

    Alison Rowles;James P.J Chong;Lamorna Brown;Mike Howell

  • Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

    Panagiotis Galanos;Konstantinos Vougas;David Walter;Alexander Polyzos

  • Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

    Xin Quan Ge;J. Julian Blow

  • How dormant origins promote complete genome replication.

    J. Julian Blow;Xin Quan Ge;Dean A. Jackson

  • The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin.

    Piotr Romanowski;Mark A. Madine;Alison Rowles;J.Julian Blow

  • A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

    J.Julian Blow;Paul Nurse

  • Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs.

    M A Sheehan;A D Mills;A M Sleeman;R A Laskey

  • Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

    A.D. Mills;J.J. Blow;J.G. White;W.B. Amos

Frequent Co-Authors

Ronald A. Laskey
Ronald A. Laskey University of Cambridge
Anton Gartner
Anton Gartner University of Dundee
Jason R. Swedlow
Jason R. Swedlow University of Dundee
Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
Jens S. Andersen
Jens S. Andersen University of Southern Denmark
Tim Hunt
Tim Hunt University of Cambridge
Michael Howell
Michael Howell The Francis Crick Institute
Melvin L. DePamphilis
Melvin L. DePamphilis National Institutes of Health
Paul Nurse
Paul Nurse The Francis Crick Institute
David M. Gilbert
David M. Gilbert Florida State University

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