D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 72 Citations 19,723 161 World Ranking 810 National Ranking 64

Research.com Recognitions

Awards & Achievements

2002 - Fellow of the Royal Society of Edinburgh

Member of the European Molecular Biology Organization (EMBO)

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Chromosome

Cell biology, Origin recognition complex, DNA replication, Control of chromosome duplication and Eukaryotic DNA replication are his primary areas of study. His work deals with themes such as Molecular biology, Cell cycle, Semiconservative replication and Cyclin A, which intersect with Cell biology. His research investigates the connection with Origin recognition complex and areas like MCM Protein which intersect with concerns in Computational biology, MCM complex and MCM Protein Complex.

His DNA replication research incorporates themes from Xenopus and Replicon. His Control of chromosome duplication research is within the category of Genetics. His study in Pre-replication complex, DNA replication factor CDT1, Licensing factor and Replication factor C is carried out as part of his Eukaryotic DNA replication studies.

His most cited work include:

  • Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5 (1189 citations)
  • Preventing re-replication of chromosomal DNA (562 citations)
  • Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. (515 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, DNA replication, Origin recognition complex, Control of chromosome duplication and Eukaryotic DNA replication. His Cell biology research includes themes of G2-M DNA damage checkpoint, Xenopus and Cell cycle, Cyclin-dependent kinase. His DNA replication research incorporates elements of Chromatin, Molecular biology and Cell division.

His study looks at the intersection of Molecular biology and topics like Cyclin A with Cyclin E. J. Julian Blow has researched Origin recognition complex in several fields, including MCM Protein, DNA replication factor CDT1, Minichromosome maintenance, ORC6 and Licensing factor. His Control of chromosome duplication research is included under the broader classification of Genetics.

He most often published in these fields:

  • Cell biology (64.85%)
  • DNA replication (57.58%)
  • Origin recognition complex (53.33%)

What were the highlights of his more recent work (between 2013-2021)?

  • DNA replication (57.58%)
  • Cell biology (64.85%)
  • Origin recognition complex (53.33%)

In recent papers he was focusing on the following fields of study:

J. Julian Blow mostly deals with DNA replication, Cell biology, Origin recognition complex, Genetics and Mitosis. Specifically, his work in DNA replication is concerned with the study of Origin of replication. His studies in Cell biology integrate themes in fields like Cell cycle, Mitotic chromosome, Xenopus and Chromosome organisation.

His Origin recognition complex study combines topics from a wide range of disciplines, such as Chromatin and DNA replication factor CDT1, Control of chromosome duplication. His studies deal with areas such as S phase and Eukaryotic DNA replication as well as Control of chromosome duplication. His research on Eukaryotic DNA replication focuses in particular on Licensing factor.

Between 2013 and 2021, his most popular works were:

  • Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing (138 citations)
  • Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells (86 citations)
  • The contribution of dormant origins to genome stability: from cell biology to human genetics. (79 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Chromosome

His primary areas of study are DNA replication, Cell biology, Genetics, Origin recognition complex and Genome instability. J. Julian Blow works in the field of DNA replication, namely DNA re-replication. His Cell biology study combines topics in areas such as Cell cycle, Cell cycle progression, Caenorhabditis elegans and Mitotic chromosome.

While the research belongs to areas of Genetics, he spends his time largely on the problem of Computational biology, intersecting his research to questions surrounding Robustness and Phenotypic plasticity. His research investigates the connection between Origin recognition complex and topics such as Control of chromosome duplication that intersect with issues in S phase. As a part of the same scientific family, he mostly works in the field of Genome instability, focusing on Phenotype and, on occasion, Effector, Ubiquitin ligase, Kinase, Downregulation and upregulation and Senescence.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5

Laurent Meijer;Annie Borgne;Odile Mulner;James P.J. Chong.
FEBS Journal (1997)

1579 Citations

Preventing re-replication of chromosomal DNA

J. Julian Blow;Anindya Dutta.
Nature Reviews Molecular Cell Biology (2005)

808 Citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle.

J. Julian Blow;Ronald A. Laskey.
Nature (1988)

748 Citations

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs.

J.Julian Blow;Ronald A. Laskey.
Cell (1986)

718 Citations

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

C Norbury;J Blow;P Nurse.
The EMBO Journal (1991)

643 Citations

Dormant origins licensed by excess Mcm2–7 are required for human cells to survive replicative stress

Xin Quan Ge;Dean A. Jackson;J. Julian Blow.
Genes & Development (2007)

586 Citations

Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin

Shusuke Tada;Anatoliy Li;Domenico Maiorano;Marcel Méchali.
Nature Cell Biology (2001)

564 Citations

Translation of Cyclin mRNA Is Necessary for Extracts of Activated Xenopus Eggs to Enter Mitosis

Jeremy Minshull;J.Julian Blow;Tim Hunt.
Cell (1989)

542 Citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

James P. J. Chong;Hiro M. Mahbubani;Chong-Yee Khoo;J. Julian Blow.
Nature (1995)

469 Citations

Excess Mcm2–7 license dormant origins of replication that can be used under conditions of replicative stress

Anna M. Woodward;Thomas Göhler;M. Gloria Luciani;Maren Oehlmann.
Journal of Cell Biology (2006)

413 Citations

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