What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include DNA replication, Origin recognition complex, Control of chromosome duplication, Genetics and Pre-replication complex.
The various areas that Marcel Méchali examines in his DNA replication study include Molecular biology, Xenopus and Plasmid.
In Molecular biology, Marcel Méchali works on issues like Chromatin, which are connected to TATA-Box Binding Protein, TAF2 and TATA-binding protein.
His Origin recognition complex research is multidisciplinary, incorporating perspectives in Licensing factor and Cell biology.
His research on Control of chromosome duplication focuses in particular on Replication factor C.
His study in Pre-replication complex is interdisciplinary in nature, drawing from both DNA replication factor CDT1 and DNA re-replication.
His most cited work include:
- Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin. (412 citations)
- Eukaryotic DNA replication origins: many choices for appropriate answers (325 citations)
- XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis (317 citations)
What are the main themes of his work throughout his whole career to date?
DNA replication, Cell biology, Molecular biology, Genetics and Origin recognition complex are his primary areas of study.
The concepts of his DNA replication study are interwoven with issues in Cell cycle and DNA synthesis.
His Cell biology research includes elements of Chromatin and Xenopus.
His Molecular biology study integrates concerns from other disciplines, such as Replication Initiation, Midblastula, Somatic cell and DNA polymerase.
His Origin recognition complex research integrates issues from Control of chromosome duplication, Pre-replication complex, DNA replication origin, Licensing factor and DNA re-replication.
His work on DNA replication factor CDT1 and Replication factor C as part of general Control of chromosome duplication study is frequently linked to Replication protein A, therefore connecting diverse disciplines of science.
He most often published in these fields:
- DNA replication (49.06%)
- Cell biology (41.51%)
- Molecular biology (32.70%)
What were the highlights of his more recent work (between 2009-2020)?
- DNA replication (49.06%)
- Genetics (30.82%)
- Cell biology (41.51%)
In recent papers he was focusing on the following fields of study:
Marcel Méchali mainly focuses on DNA replication, Genetics, Cell biology, Control of chromosome duplication and Origin recognition complex.
His DNA replication study frequently intersects with other fields, such as Chromatin.
His research in Chromatin intersects with topics in Xenopus, Molecular biology, Homologous recombination and DNA repair.
The study incorporates disciplines such as Enhancer and G-quadruplex in addition to Cell biology.
His Eukaryotic DNA replication research extends to Control of chromosome duplication, which is thematically connected.
His research investigates the connection between Origin recognition complex and topics such as Licensing factor that intersect with issues in Interkinesis and Meiosis II.
Between 2009 and 2020, his most popular works were:
- Eukaryotic DNA replication origins: many choices for appropriate answers (325 citations)
- DNA replication origin activation in space and time (249 citations)
- Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features (247 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Genetics, DNA replication, Origin recognition complex, Pre-replication complex and Control of chromosome duplication.
His study brings together the fields of Cancer research and Genetics.
He studies Origin of replication, a branch of DNA replication.
The Origin recognition complex study combines topics in areas such as Chromatin and DNA replication origin.
His studies deal with areas such as Cell biology, DNA replication factor CDT1 and DNA re-replication as well as Pre-replication complex.
He works mostly in the field of Cell biology, limiting it down to topics relating to S phase and, in certain cases, MCM Protein Complex and G2 phase.
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