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Genetics
France
2024
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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Genetics

D-Index
81
Citations
24720
World Ranking
1523
National Ranking
59

Medicine

D-Index
81
Citations
24495
World Ranking
16629
National Ranking
543

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Thierry Soussi is affiliated with Université Paris Cité in France and has contributed significantly to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Oncology, Molecular Biology, Cancer Research, Genetics, and Pulmonary and Respiratory Medicine.

Their main topics of investigation include:

  • Cancer-related Molecular Pathways
  • Cancer Genomics and Diagnostics
  • Chronic Lymphocytic Leukemia Research
  • Epigenetics and DNA Methylation
  • Advanced Breast Cancer Therapies
  • Acute Myeloid Leukemia Research
  • Genomic variations and chromosomal abnormalities

Thierry Soussi has published research in several notable journals with frequent appearances in:

  • Cell Death and Differentiation
  • Leukemia
  • Scientific Reports
  • American Journal of Hematology
  • British Journal of Haematology

Among their recent publications are:

  • Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene, 2020, Cell Death and Differentiation
  • Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations, 2025, Nature Genetics
  • Comprehensive assessment of TP53 loss of function using multiple combinatorial mutagenesis libraries, 2020, Scientific Reports
  • TP53: the unluckiest of genes?, 2024, Cell Death and Differentiation
  • ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update, 2024, Leukemia

They frequently collaborate with several researchers, including:

  • Panagiotis Baliakas
  • Grégory Lazarian
  • Florence Cymbalista
  • Fanny Baran-Marszak
  • Andreas C. Joerger

Best Publications

  • Database of p53 gene somatic mutations in human tumors and cell lines.

    M. Hollstein;K. Rice;M. S. Greenblatt;T. Soussi

  • Assessing TP53 status in human tumours to evaluate clinical outcome.

    Thierry Soussi;Christophe Béroud

  • Structural aspects of the p53 protein in relation to gene evolution.

    Soussi T;Caron de Fromentel C;May P

  • p53 Antibodies in the Sera of Patients with Various Types of Cancer: A Review

    Thierry Soussi

  • TP53 tumor suppressor gene: a model for investigating human mutagenesis.

    Claude Caron De Fromentel;Thierry Soussi

  • Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation.

    M. Hollstein;Benny Shomer;M. Greenblatt;Thierry Soussi

  • Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas.

    Lawrence A. Donehower;Thierry Soussi;Anil Korkut;Yuexin Liu

  • Multifactorial analysis of p53 alteration in human cancer: a review.

    T. Soussi;Y. Legros;R. Lubin;K. Ory

  • The TP53 Colorectal Cancer International Collaborative Study on the Prognostic and Predictive Significance of p53 Mutation: Influence of Tumor Site, Type of Mutation, and Adjuvant Treatment

    Antonio Russo;Viviana Bazan;Barry Iacopetta;David Kerr

  • Shaping genetic alterations in human cancer: the p53 mutation paradigm.

    Thierry Soussi;Klas G. Wiman

  • The p53 tumor suppressor gene: from molecular biology to clinical investigation.

    Thierry Soussi

  • Lymphomas in Patients With Sjögren's Syndrome Are Marginal Zone B-Cell Neoplasms, Arise in Diverse Extranodal and Nodal Sites, and Are Not Associated With Viruses

    Bruno Royer;Dominique Cazals-Hatem;Jean Sibilia;Felix Agbalika

  • TP53 mutations in human cancer: database reassessment and prospects for the next decade.

    Bernard Leroy;Martha Anderson;Thierry Soussi;Thierry Soussi

  • APC Gene: Database of Germline and Somatic Mutations in Human Tumors and Cell Lines

    Christophe Béroud;Thierry Soussi

  • Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

    Pierre Hainaut;Thierry Soussi;Benny Shomer;M. Hollstein

  • p53 mutation heterogeneity in cancer

    T. Soussi;Guillermina Lozano

  • p53 website and analysis of p53 gene mutations in human cancer: forging a link between epidemiology and carcinogenesis.

    Thierry Soussi;Karim Dehouche;Christophe Béroud

  • Serum p53 antibodies as early markers of lung cancer

    Richard Lubin;Gerard Zalcman;Laurence Bouchet;Jean Trédaniel

  • The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.

    Beata Schlichtholz;Yann Legros;Daniel Gillet;Claire Gaillard

  • p53 alterations in human cancer: more questions than answers.

    T Soussi;T Soussi

Frequent Co-Authors

Christophe Béroud
Christophe Béroud Aix-Marseille University
Chikashi Ishioka
Chikashi Ishioka Tohoku University
Guido Kroemer
Guido Kroemer Université Paris Cité
Marcel Méchali
Marcel Méchali Centre national de la recherche scientifique, CNRS
Oliver Kepp
Oliver Kepp Institut Gustave Roussy
Šárka Pospíšilová
Šárka Pospíšilová Masaryk University
Catherine Boileau
Catherine Boileau Université Paris Cité
Luigi Maiuri
Luigi Maiuri European Institute
Mehmet Ozturk
Mehmet Ozturk Izmir Biomedicine and Genome Center
Monica Hollstein
Monica Hollstein University of Leeds

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