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Genetics

D-Index
44
Citations
6941
World Ranking
4265
National Ranking
100

Overview

Alberto Inga is affiliated with the University of Trento in Italy. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology and Oncology. The work includes significant contributions in Cancer Research and Biotechnology.

They have published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancers, Nucleic Acids Research, SSRN Electronic Journal, and Cell Reports. These publications cover topics related to RNA modifications and cancer, RNA research and splicing, RNA and protein synthesis mechanisms, cancer-related molecular pathways, epigenetics and DNA methylation, ubiquitin and proteasome pathways, and cancer-related molecular mechanisms research.

Recent papers authored or coauthored by Alberto Inga include:

  • SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy, 2020, Nature Cell Biology
  • Structural and Drug Targeting Insights on Mutant p53, 2021, Cancers
  • Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer, 2021, Cell Systems
  • A selective p53 activator and anticancer agent to improve colorectal cancer therapy, 2021, Cell Reports
  • Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30, 2020, Cell Reports

Frequent coauthors collaborating with Alberto Inga include Erik Dassi, Annalisa Rossi, Paola Monti, Meriem Hadjer Hamadou, and Alessandra Bisio.

Their research covers a variety of scientific topics, notably:

  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Cancer-related molecular mechanisms research

Alberto Inga's studies have contributed to a better understanding of molecular mechanisms in cancer biology and RNA function, reflecting an interdisciplinary approach involving molecular biology, oncology, and biochemistry.

Best Publications

  • The expanding universe of p53 targets

    Daniel Menendez;Alberto Inga;Michael A. Resnick

  • A highly specific SpCas9 variant is identified by in vivo screening in yeast.

    Antonio Casini;Michele Olivieri;Gianluca Petris;Claudia Montagna

  • Differential Transactivation by the p53 Transcription Factor Is Highly Dependent on p53 Level and Promoter Target Sequence

    Alberto Inga;Francesca Storici;Thomas A. Darden;Michael A. Resnick

  • The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis

    Bernard Leroy;Jean Louis Fournier;Chikashi Ishioka;Paola Monti

  • Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

    Michael A. Resnick;Alberto Inga

  • p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.

    Paola Campomenosi;Paola Monti;Anna Aprile;Angelo Abbondandolo;Angelo Abbondandolo

  • Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway.

    Tina Uroda;Eleni Anastasakou;Annalisa Rossi;Jean-Marie Teulon

  • Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation

    Daniel J. Tomso;Alberto Inga;Daniel Menendez;Gary S. Pittman

  • Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity.

    Zdenek Andrysik;Zdenek Andrysik;Matthew D Galbraith;Matthew D Galbraith;Anna L Guarnieri;Anna L Guarnieri;Sara Zaccara

  • Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53

    Jennifer J. Jordan;Jennifer J. Jordan;Daniel Menendez;Alberto Inga;Maher Nourredine

  • The Ribonucleic Complex HuR-MALAT1 Represses CD133 Expression and Suppresses Epithelial-Mesenchymal Transition in Breast Cancer.

    Elisa Latorre;Elisa Latorre;Stephana Carelli;Ivan Raimondi;Vito D'Agostino

  • The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes.

    Daniel Menendez;Alberto Inga;Michael A. Resnick

  • More targets, more pathways and more clues for mutant p53

    Sonia Iolanda Garritano;A Inga;Federica Gemignani;Stefano Landi

  • A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

    Daniel Menendez;Oliver Krysiak;Alberto Inga;Bianca Krysiak

  • Altered-Function p53 Missense Mutations Identified in Breast Cancers Can Have Subtle Effects on Transactivation

    Jennifer J. Jordan;Alberto Inga;Kathleen Conway;Sharon Edmiston

  • Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

    Paola Monti;Chiara Perfumo;Alessandra Bisio;Yari Ciribilli

  • Tumour p53 mutations exhibit promoter selective dominance over wild type p53.

    Paola Monti;Paola Campomenosi;Paola Campomenosi;Yari Ciribilli;Raffaella Iannone

  • Functional evolution of the p53 regulatory network through its target response elements

    Anil G. Jegga;Alberto Inga;Daniel Menendez;Bruce J. Aronow

  • A functional genetic study identifies HAND1 mutations in septation defects of the human heart

    Stella Marie Reamon-Buettner;Yari Ciribilli;Ilaria Traverso;Beate Kuhls

  • p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

    Alberto Inga;Paola Monti;Gilberto Fronza;Tom Darden

Frequent Co-Authors

Michael A. Resnick
Michael A. Resnick National Institutes of Health
Alessandro Quattrone
Alessandro Quattrone University of Trento
Francesca Demichelis
Francesca Demichelis University of Trento
Douglas A. Bell
Douglas A. Bell National Institutes of Health
Olivier Elemento
Olivier Elemento Cornell University
Anil G. Jegga
Anil G. Jegga Cincinnati Children's Hospital Medical Center
Joaquín M. Espinosa
Joaquín M. Espinosa University of Colorado Anschutz Medical Campus
Richard Iggo
Richard Iggo University of Bordeaux
Madalena Pinto
Madalena Pinto University of Porto
Mark A. Rubin
Mark A. Rubin University of Bern

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