World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11392
World Ranking
15557
National Ranking
628

Overview

Richard Iggo is affiliated with the University of Bordeaux in France. Their research focuses primarily on biochemistry, genetics, and molecular biology, with significant contributions to the fields of medicine, cancer research, molecular biology, oncology, pulmonary and respiratory medicine, and genetics.

The scientist's work covers a range of topics within cancer research, including:

  • Breast Cancer Treatment Studies
  • S100 Proteins and Annexins
  • Cancer Genomics and Diagnostics
  • Cancer Cells and Metastasis
  • Advanced Breast Cancer Therapies
  • Prostate Cancer Treatment and Research
  • HER2/EGFR in Cancer Research

Among recent publications authored or co-authored by Richard Iggo are:

  • The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer (2021, Nature Medicine)
  • Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer (2021, Cell Reports)
  • ACSM1 and ACSM3 Regulate Fatty Acid Metabolism to Support Prostate Cancer Growth and Constrain Ferroptosis (2024, Cancer Research)
  • TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape (2022, PLoS Pathogens)
  • A genome-scale CRISPR knock-out screen in chronic myeloid leukemia identifies novel drug resistance mechanisms along with intrinsic apoptosis and MAPK signaling (2020, Cancer Medicine)

Frequent collaborators in their research include:

  • Wayne D. Tilley
  • Theresa E. Hickey
  • Luke A. Selth
  • Gaëtan MacGrogan
  • Valérie Prouzet-Mauleon

Richard Iggo publishes regularly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Methods in molecular biology
  • Research Square (Research Square)
  • Nature Medicine

Best Publications

  • Induction of an interferon response by RNAi vectors in mammalian cells

    Alan J Bridge;Stephanie Pebernard;Annick Ducraux;Anne-Laure Nicoulaz

  • Identification of molecular apocrine breast tumours by microarray analysis

    Pierre Farmer;Herve Bonnefoi;Véronique Becette;Michele Tubiana-Hulin

  • Identification of molecular apocrine breast tumours by microarray analysis

    P Farmer;H Bonnefoi;V Becette;M Tubiana-Hulin

  • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

    Pierre Farmer;Pierre Farmer;Pierre Farmer;Hervé Bonnefoi;Pascale Anderle;David Cameron;David Cameron

  • Screening patients for heterozygous p53 mutations using a functional assay in yeast.

    Chikashi Ishioka;Thierry Frebourg;Yu Xin Yan;Marc Vidal

  • Retraction--Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial.

    Hervé Bonnefoi;Anil Potti;Mauro Delorenzi;Louis Mauriac

  • Patient-derived xenograft (PDX) models in basic and translational breast cancer research

    Lacey E. Dobrolecki;Susie D. Airhart;Denis G. Alferez;Samuel Aparicio

  • Field cancerisation and polyclonal p53 mutation in the upper aero-digestive tract.

    Waridel F;Waridel F;Estreicher A;Bron L;Flaman Jm

  • Determinants of interferon-stimulated gene induction by RNAi vectors

    Stephanie Pebernard;Richard D. Iggo

  • Mammalian p53 can function as a transcription factor in yeast

    E Schärer;R Iggo

  • A rapid PCR fidelity assay

    Jean michel Flaman;Thierry Frebourg;Viviane Moreau;Francoise Charbonnier

  • Functional Analysis of Human MLH1 Variants Using Yeast and In vitro Mismatch Repair Assays

    Masanobu Takahashi;Hideki Shimodaira;Corinne Andreutti-Zaugg;Richard Iggo

  • Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses.

    Connie Chao;Manfred Hergenhahn;Matthias D. Kaeser;Zhiqun Wu

  • The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer

    Theresa E. Hickey;Luke A. Selth;Luke A. Selth;Kee Ming Chia;Geraldine Laven-Law

  • p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.

    Paola Campomenosi;Paola Monti;Anna Aprile;Angelo Abbondandolo;Angelo Abbondandolo

  • TP53 status for prediction of sensitivity to taxane versus non-taxane neoadjuvant chemotherapy in breast cancer (EORTC 10994/BIG 1-00): a randomised phase 3 trial

    Hervé Bonnefoi;Hervé Bonnefoi;Martine Piccart;Jan Bogaerts;Louis Mauriac

  • Increased apoptosis induction by 121F mutant p53.

    Elisabeth Saller;Edward Tom;Michele Brunori;Michèle Otter

  • Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells

    Matthias D. Kaeser;Stephanie Pebernard;Richard D. Iggo

  • The human tumour suppressor gene p53 is alternatively spliced in normal cells.

    J M Flaman;F Waridel;A Estreicher;A Vannier

  • Evidence of frequent recombination among human adenoviruses.

    Alexander N. Lukashev;Olga E. Ivanova;Tatiana P. Eremeeva;Richard D. Iggo

Frequent Co-Authors

Jonas Bergh
Jonas Bergh Karolinska Institute
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Thierry Frebourg
Thierry Frebourg Grenoble Alpes University
Chikashi Ishioka
Chikashi Ishioka Tohoku University
Jacek Jassem
Jacek Jassem Gdańsk Medical University
Mario Campone
Mario Campone Grenoble Alpes University
Stephen H. Friend
Stephen H. Friend Sage Bionetworks
Alberto Inga
Alberto Inga University of Trento
Hiroshi Abe
Hiroshi Abe Nagoya University
Thierry Soussi
Thierry Soussi Université Paris Cité

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