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Molecular Biology
Israel
2026
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Genetics and Molecular Biology
Israel
2024

D-Index & Metrics

Molecular Biology

D-Index
97
Citations
30187
World Ranking
598
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Israel Leader Award
  • 2025 - Research.com Molecular Biology in Israel Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Israel Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Israel Leader Award
  • 2023 - Research.com Molecular Biology in Israel Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Israel Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Varda Rotter is affiliated with the Weizmann Institute of Science in Israel, focusing primarily on research within biochemistry, genetics, and molecular biology as well as medicine. Their work intersects multiple specialized subfields, including molecular biology, oncology, cancer research, hematology, and biotechnology.

The scientist's research covers several main topics, namely:

  • Cancer-related Molecular Pathways
  • Cancer Genomics and Diagnostics
  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • Ubiquitin and proteasome pathways
  • Acute Myeloid Leukemia Research
  • Cancer Research and Treatments

Varda Rotter's recent papers illustrate active involvement in cancer biology and cellular signaling studies. Notable publications include:

  • "Principles of signaling pathway modulation for enhancing human naive pluripotency induction," 2021, Cell Stem Cell
  • "Mutant p53 oncogenicity: dominant-negative or gain-of-function?," 2020, Carcinogenesis
  • "Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis," 2023, Nature Communications
  • "Visual barcodes for clonal-multiplexing of live microscopy-based assays," 2022, Nature Communications
  • "Egr1 regulates regenerative senescence and cardiac repair," 2024, Nature Cardiovascular Research

Their publications have appeared most frequently in Nature Communications and Carcinogenesis, along with contributions in Cell Stem Cell, Nature Cardiovascular Research, and bioRxiv (Cold Spring Harbor Laboratory).

Frequent co-authors collaborating with Varda Rotter include Moshe Oren, Perry Tal, Ayush Attery, Himanshi Agarwal, and David Malkin. These collaborations reflect a network within cancer and molecular biology research communities.

Varda Rotter has been recognized as a member of the European Molecular Biology Organization (EMBO), reflecting acknowledgment within the professional scientific community.

Best Publications

  • When mutants gain new powers: news from the mutant p53 field

    Ran Brosh;Varda Rotter

  • Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis

    Noa Rivlin;Ran Brosh;Moshe Oren;Varda Rotter

  • Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation

    Luis F. Parada;Hartmut Land;Robert A. Weinberg;David Wolf

  • Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

    Alex Sigal;Varda Rotter

  • Mutant p53 Gain-of-Function in Cancer

    Moshe Oren;Varda Rotter

  • Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

    David Wolf;Varda Rotter

  • Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

    Tomer Cooks;Ioannis S. Pateras;Ohad Tarcic;Hilla Solomon

  • Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis.

    G. Shaulsky;N. Goldfinger;Avri Ben-Ze'ev;V. Rotter

  • Nitric oxide-induced cellular stress and p53 activation in chronic inflammation.

    Lorne J. Hofseth;Shin'ichi Saito;S. Perwez Hussain;Michael G. Espey

  • ‘Cancer associated fibroblasts’ – more than meets the eye

    Shalom Madar;Ido Goldstein;Varda Rotter

  • Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene

    David Wolf;Nicholas Harris;Varda Rotter

  • Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

    Gilad Landan;Netta Mendelson Cohen;Zohar Mukamel;Amir Bar

  • c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif.

    D. Reisman;N. B. Elkind;B. Roy;J. Beamon

  • Human p53 gene localized to short arm of chromosome 17

    Carl Miller;T. Mohandas;D. Wolf;M. Prokocimer

  • p53 Plays a Regulatory Role in Differentiation and Apoptosis of Central Nervous System-Associated Cells

    O Eizenberg;A Faber-Elman;E Gottlieb;M Oren

  • Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

    Perry Stambolsky;Yuval Tabach;Giulia Fontemaggi;Lilach Weisz

  • Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells.

    Lilach Weisz;Alexander Damalas;Michalis Liontos;Panagiotis Karakaidos

  • Transcription regulation by mutant p53

    L Weisz;M Oren;V Rotter

  • p53-dependent cell cycle control: response to genotoxic stress.

    Dov Schwartz;Varda Rotter

  • Subcellular distribution of the p53 protein during the cell cycle of Balb/c 3T3 cells.

    G Shaulsky;A Ben-Ze'ev;V Rotter

Frequent Co-Authors

Naomi Goldfinger
Naomi Goldfinger Weizmann Institute of Science
Moshe Oren
Moshe Oren Weizmann Institute of Science
Irun R. Cohen
Irun R. Cohen Weizmann Institute of Science
Lars A. Akslen
Lars A. Akslen University of Bergen
Curtis C. Harris
Curtis C. Harris National Institutes of Health
Dana G. Wolf
Dana G. Wolf Hebrew University of Jerusalem
Gad Shaulsky
Gad Shaulsky Baylor College of Medicine
Giovanni Blandino
Giovanni Blandino McMaster University
Ansgar W. Lohse
Ansgar W. Lohse Universität Hamburg
Guillermina Lozano
Guillermina Lozano The University of Texas MD Anderson Cancer Center

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