D-Index & Metrics Best Publications
Molecular Biology
Israel
2023
Genetics and Molecular Biology
Israel
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 91 Citations 25,180 282 World Ranking 429 National Ranking 4

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in Israel Leader Award

2022 - Research.com Genetics and Molecular Biology in Israel Leader Award

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Cancer

Varda Rotter mostly deals with Cancer research, Molecular biology, Mutant, Gene and Carcinogenesis. Her biological study spans a wide range of topics, including Cancer, Cell cycle, Gene rearrangement, Immunology and Tumor suppressor gene. Her Molecular biology research includes elements of Cell culture, Transfection, Promoter, Gene expression and Transcription factor.

Varda Rotter has researched Mutant in several fields, including Cancer cell, Malignant transformation and Mutation. Many of her studies on Gene involve topics that are commonly interrelated, such as DNA. Her biological study spans a wide range of topics, including Cell cycle checkpoint, Regulation of gene expression, Drug resistance and Cell biology.

Her most cited work include:

  • When mutants gain new powers: news from the mutant p53 field (797 citations)
  • Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. (576 citations)
  • Mutant p53 Gain-of-Function in Cancer (512 citations)

What are the main themes of her work throughout her whole career to date?

Molecular biology, Cell biology, Cancer research, Mutant and Gene are her primary areas of study. The various areas that she examines in her Molecular biology study include Cell culture, Transfection, Gene expression, Regulation of gene expression and Antibody. Her Cell biology research includes themes of Cellular differentiation, Apoptosis, Cell cycle, Programmed cell death and Transcription factor.

Her research investigates the connection between Cancer research and topics such as Carcinogenesis that intersect with issues in Stem cell and Malignant transformation. The concepts of her Mutant study are interwoven with issues in Cancer cell, Downregulation and upregulation, Protein structure and Mutation. Her research on Gene concerns the broader Genetics.

She most often published in these fields:

  • Molecular biology (33.67%)
  • Cell biology (29.67%)
  • Cancer research (25.33%)

What were the highlights of her more recent work (between 2012-2021)?

  • Cell biology (29.67%)
  • Mutant (22.00%)
  • Cancer research (25.33%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Cell biology, Mutant, Cancer research, Stem cell and Carcinogenesis. Her research integrates issues of Genetics, Transcription factor, Wild type, Regulation of gene expression and Gene isoform in her study of Cell biology. Her Mutant research incorporates elements of Cancer cell, Molecular biology, Stromal cell and Mutation.

Her Cancer research research integrates issues from Cancer, Metastasis, Mesenchymal stem cell and Immunology. Her studies in Stem cell integrate themes in fields like Embryonic stem cell, Induced pluripotent stem cell, Cell type and DNA repair. Her study in Carcinogenesis is interdisciplinary in nature, drawing from both Tumor progression and Somatic cell.

Between 2012 and 2021, her most popular works were:

  • Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer (259 citations)
  • ‘Cancer associated fibroblasts’ – more than meets the eye (242 citations)
  • Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery (98 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

The scientist’s investigation covers issues in Cancer research, Cell biology, Mutant, Stem cell and Cancer stem cell. She has included themes like Immunology, KLF4, RNA interference, Colorectal cancer and Mesenchymal stem cell in her Cancer research study. Varda Rotter studied Cell biology and Malignant transformation that intersect with Regenerative medicine, Endothelial stem cell, Clinical uses of mesenchymal stem cells, Cellular differentiation and Carcinogenesis.

Her Mutant study combines topics from a wide range of disciplines, such as Mutation, Molecular biology, Metastasis and Peptide. Her Mutation research is multidisciplinary, incorporating perspectives in Cancer cell, Lysophosphatidic acid and Somatic evolution in cancer. Her Molecular biology study incorporates themes from Cell culture, Gene knockdown, Wild type, Protein structure and DNA-binding domain.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

When mutants gain new powers: news from the mutant p53 field

Ran Brosh;Varda Rotter.
Nature Reviews Cancer (2009)

1216 Citations

Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis

Noa Rivlin;Ran Brosh;Moshe Oren;Varda Rotter.
Genes & Cancer (2011)

963 Citations

Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.

Alex Sigal;Varda Rotter.
Cancer Research (2000)

957 Citations

Mutant p53 Gain-of-Function in Cancer

Moshe Oren;Varda Rotter.
Cold Spring Harbor Perspectives in Biology (2010)

833 Citations

Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

David Wolf;Varda Rotter.
Proceedings of the National Academy of Sciences of the United States of America (1985)

556 Citations

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis.

G. Shaulsky;N. Goldfinger;Avri Ben-Ze'ev;V. Rotter.
Molecular and Cellular Biology (1990)

487 Citations

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

Tomer Cooks;Ioannis S. Pateras;Ohad Tarcic;Hilla Solomon.
Cancer Cell (2013)

435 Citations

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation.

Lorne J. Hofseth;Shin'ichi Saito;S. Perwez Hussain;Michael G. Espey.
Proceedings of the National Academy of Sciences of the United States of America (2003)

406 Citations

‘Cancer associated fibroblasts’ – more than meets the eye

Shalom Madar;Ido Goldstein;Varda Rotter.
Trends in Molecular Medicine (2013)

367 Citations

Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene

David Wolf;Nicholas Harris;Varda Rotter.
Cell (1984)

354 Citations

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