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Molecular Biology
USA
2026
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Genetics and Molecular Biology
USA
2024

D-Index & Metrics

Molecular Biology

D-Index
164
Citations
178986
World Ranking
52
National Ranking
35

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2020 - Fellow of the American Psychological Association (APA)
  • 2001 - Albany Medical Center Prize in Medicine and Biomedical Research
  • 2000 - Keio Medical Science Prize, Keio University, Tokyo, Japan
  • 1999 - Charles S. Mott Prize, General Motors Cancer Research Foundation
  • 1998 - Louisa Gross Horwitz Prize, Columbia University
  • 1998 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 1995 - Member of the National Academy of Medicine (NAM)
  • 1991 - Member of the National Academy of Sciences
  • 1990 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Arnold J. Levine is affiliated with the Institute for Advanced Study in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their principal fields and subfields of study include molecular biology, oncology, cancer research, immunology, and biotechnology.

Their research topics cover various areas related to cancer and molecular pathways, including cancer-related molecular pathways, epigenetics and DNA methylation, cancer genomics and diagnostics, ubiquitin and proteasome pathways, hedgehog signaling pathway studies, cancer research and treatments, and immunotherapy and immune responses.

Levine has a series of notable recent publications, illustrating their ongoing contributions to these fields. These include:

  • p53: 800 million years of evolution and 40 years of discovery (2020, Nature Reviews. Cancer)
  • P53 and The Immune Response: 40 Years of Exploration-A Plan for the Future (2020, International Journal of Molecular Sciences)
  • Spontaneous and inherited TP53 genetic alterations (2021, Oncogene)

They have coauthored multiple papers with several frequent collaborators, including Benjamin D. Greenbaum, Pierre Hainaut, Claire Freyçon, Joseph O. Deasy, and Allen Tannenbaum. These collaborations have contributed to a broad scope of studies in related areas.

Levine regularly publishes in several venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Death and Differentiation
  • Nature Aging
  • Nature
  • Nature Communications

Their body of work has garnered recognition through a series of awards and honors, such as membership in the National Academy of Sciences (1991) and the National Academy of Medicine (1995). In addition, they have received prestigious prizes including the Albany Medical Center Prize in Medicine and Biomedical Research (2001), the Keio Medical Science Prize from Keio University, Tokyo (2000), the Charles S. Mott Prize from the General Motors Cancer Research Foundation (1999), the Louisa Gross Horwitz Prize from Columbia University (1998), and the Paul Ehrlich and Ludwig Darmstaedter Prize (1998). More recently, they were named a Fellow of the American Psychological Association in 2020 and a Fellow of the John Simon Guggenheim Memorial Foundation in 1990.

Best Publications

  • The Sequence of the Human Genome

    J. Craig Venter;Mark D. Adams;Eugene W. Myers;Peter W. Li

  • p53, the Cellular Gatekeeper for Growth and Division

    Arnold J Levine

  • Surfing the p53 network

    Bert Vogelstein;David Lane;Arnold J. Levine

  • Stochastic Gene Expression in a Single Cell

    Michael B. Elowitz;Arnold J. Levine;Eric D. Siggia;Peter S. Swain

  • The p53 tumour suppressor gene

    Arnold J. Levine;Jamil Momand;Cathy A. Finlay

  • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

    Martin Scheffner;Bruce A. Werness;Jon M. Huibregtse;Arnold J. Levine

  • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

    Jamil Momand;Gerard P. Zambetti;David C. Olson;Donna George

  • Association of human papillomavirus types 16 and 18 E6 proteins with p53.

    Bruce A. Werness;Arnold J. Levine;Peter M. Howley

  • Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.

    Paul H. Kussie;Svetlana Gorina;Vincent Marechal;Brian Elenbaas

  • The p53 proto-oncogene can act as a suppressor of transformation

    Cathy A. Finlay;Philip W. Hinds;Arnold J. Levine

  • The p53 pathway: positive and negative feedback loops

    Sandra L Harris;Arnold J Levine

  • The p53-mdm-2 autoregulatory feedback loop

    Xiangwei Wu;J. H. Bayle;D. Olson;A. J. Levine

  • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor.

    Zhenyu Yue;Shengkan Jin;Chingwen Yang;Arnold J. Levine

  • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells.

    Daniel I.H. Linzer;Arnold J. Levine

  • Transcriptional control of human p53-regulated genes

    Todd Riley;Todd Riley;Eduardo Sontag;Patricia Chen;Arnold Levine

  • The first 30 years of p53: growing ever more complex

    Arnold J. Levine;Moshe Oren

  • Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis.

    Megan Cully;Han You;Arnold J. Levine;Tak W. Mak

  • The coordinate regulation of the p53 and mTOR pathways in cells.

    Zhaohui Feng;Haiyan Zhang;Arnold J. Levine;Shengkan Jin

  • The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes

    Arnold J. Levine;Anna M. Puzio-Kuter

  • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

    C A Finlay;P W Hinds;T H Tan;D Eliyahu

Frequent Co-Authors

Wenwei Hu
Wenwei Hu Rutgers, The State University of New Jersey
Zhaohui Feng
Zhaohui Feng Rutgers, The State University of New Jersey
Thomas Shenk
Thomas Shenk Princeton University
Raul Rabadan
Raul Rabadan Columbia University
Harlan Robins
Harlan Robins Adaptive Biotechnologies (United States)
Diane Pennica
Diane Pennica Genentech
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Maureen E. Murphy
Maureen E. Murphy The Wistar Institute
Guillermina Lozano
Guillermina Lozano The University of Texas MD Anderson Cancer Center
Laura H. Tang
Laura H. Tang Memorial Sloan Kettering Cancer Center

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