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Biology and Biochemistry

D-Index
71
Citations
25592
World Ranking
6525
National Ranking
3036

Overview

Zhaohui Feng is affiliated with Rutgers, The State University of New Jersey in the United States. Their scholarly activity spans biochemistry, genetics, and molecular biology, with significant engagement in medicine. The scientist's research focuses prominently on molecular biology and oncology, particularly cancer research, with contributions also in immunology and genetics.

Their main research topics are centered around cancer-related molecular pathways and the intersection of cancer, hypoxia, and metabolism. Additional thematic areas include cytokine signaling pathways and interactions, RNA modifications in cancer, immune cell function and interaction, interferon and immune responses, as well as epigenetics and DNA methylation.

Zhaohui Feng has published research in several high-impact venues. Frequent publication outlets include:

  • Nature Communications
  • Cancer Research
  • Journal of Molecular Cell Biology
  • Journal of Clinical Investigation
  • Cell Death and Disease

Recent papers authored or co-authored by this researcher cover a range of topics related to tumor biology and cancer therapeutics. Selected recent works include:

  • Gain-of-function mutant p53 in cancer progression and therapy, 2020, Journal of Molecular Cell Biology
  • The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway, 2020, International Journal of Molecular Sciences
  • The Interplay Between Tumor Suppressor p53 and Hypoxia Signaling Pathways in Cancer, 2021, Frontiers in Cell and Developmental Biology
  • Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression, 2020, Journal of Clinical Investigation
  • The emerging role of leukemia inhibitory factor in cancer and therapy, 2020, Pharmacology & Therapeutics

The scientist collaborates frequently with several co-authors, reflecting a network of research contributors. These frequent collaborators include:

  • Wenwei Hu
  • Jianming Wang
  • Cen Zhang
  • Chun-Yuan Chang
  • Lanjing Zhang

Best Publications

  • Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

    Andrei V. Krivtsov;David Twomey;David Twomey;Zhaohui Feng;Matthew C. Stubbs

  • The coordinate regulation of the p53 and mTOR pathways in cells.

    Zhaohui Feng;Haiyan Zhang;Arnold J. Levine;Shengkan Jin

  • Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

    Wenwei Hu;Cen Zhang;Rui Wu;Yvonne Sun

  • MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L

    Kathrin M. Bernt;Nan Zhu;Amit U. Sinha;Sridhar Vempati

  • The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

    Yingzi Wang;Andrei Krivtsov;Amit U. Sinha;Trista Elizabeth North;Trista Elizabeth North

  • The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways

    Zhaohui Feng;Wenwei Hu;Elisa de Stanchina;Angelika K. Teresky

  • H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

    Andrei V. Krivtsov;Zhaohui Feng;Madeleine E. Lemieux;Joerg Faber

  • p53 regulates maternal reproduction through LIF

    Wenwei Hu;Zhaohui Feng;Angelika K. Teresky;Arnold J. Levine;Arnold J. Levine

  • Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair

    Zhaohui Feng;Wenwei Hu;Yu Hu;Moon-shong Tang

  • Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

    Cen Zhang;Meihua Lin;Rui Wu;Xiaowen Wang

  • The Regulation of Energy Metabolism and the IGF-1/mTOR Pathways by the p53 Protein

    Zhaohui Feng;Arnold J. Levine;Arnold J. Levine

  • Coordination and communication between the p53 and IGF-1–AKT–TOR signal transduction pathways

    Arnold J. Levine;Zhaohui Feng;Tak W. Mak;Han You

  • Tumour-associated mutant p53 drives the Warburg effect.

    Cen Zhang;Juan Liu;Yingjian Liang;Rui Wu

  • Negative regulation of tumor suppressor p53 by microRNA miR-504.

    Wenwei Hu;Chang S. Chan;Rui Wu;Cen Zhang

  • The major lipid peroxidation product, trans- 4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

    Wenwei Hu;Zhaohui Feng;Jamie Eveleigh;Ganesh Iyer

  • Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older populations

    Zhaohui Feng;Wenwei Hu;Angelika K Teresky;Eva Hernando

  • Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.

    Xuetian Yue;Yuhan Zhao;Yang Xu;Min Zheng

  • Tumor suppressor p53 and its mutants in cancer metabolism.

    Juan Liu;Cen Zhang;Wenwei Hu;Zhaohui Feng

  • Tumor suppressor p53 meets microRNAs

    Zhaohui Feng;Cen Zhang;Rui Wu;Wenwei Hu

  • Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML.

    Florian H. Heidel;Lars Bullinger;Lars Bullinger;Zhaohui Feng;Zhaohui Feng;Zhu Wang;Zhu Wang

Frequent Co-Authors

Wenwei Hu
Wenwei Hu Rutgers, The State University of New Jersey
Arnold J. Levine
Arnold J. Levine Institute for Advanced Study
Bruce G. Haffty
Bruce G. Haffty Rutgers, The State University of New Jersey
William N. Rom
William N. Rom New York University
Shantu Amin
Shantu Amin Pennsylvania State University
Frederick A. Beland
Frederick A. Beland National Center for Toxicological Research
Mien Chie Hung
Mien Chie Hung China Medical University
Max Costa
Max Costa New York University
Eileen White
Eileen White Rutgers, The State University of New Jersey
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center

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