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Molecular Biology

D-Index
65
Citations
50628
World Ranking
1636
National Ranking
827

Overview

Maureen E. Murphy is affiliated with The Wistar Institute in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on Molecular Biology, Oncology, and Cancer Research among the subfields.

The scientist's work covers multiple specialized topics, including:

  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Ferroptosis and cancer prognosis
  • Cancer, Lipids, and Metabolism
  • Viral-associated cancers and disorders
  • Cytomegalovirus and herpesvirus research

Recent publications by Maureen E. Murphy include the following papers:

  • RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance, 2020, Nature
  • Functional interplay among thiol-based redox signaling, metabolism, and ferroptosis unveiled by a genetic variant of TP53, 2020, Proceedings of the National Academy of Sciences
  • African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin, 2020, Nature Communications
  • PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis, 2022, Journal of Biological Chemistry
  • A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers, 2020, Cancer Research

The scientist collaborates frequently with several coauthors, including:

  • Alexandra Indeglia
  • Andrew V. Kossenkov
  • Thibaut Barnoud
  • Julia I-Ju Leu
  • Donna L. George

Publication venues where Maureen E. Murphy has frequently appeared include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • eLife
  • Nature

In addition to journal publications, Maureen E. Murphy has contributed to book publications, notably one titled Déborder la négritude, published in 2020 by the Centre National de la Recherche Scientifique.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

    Brent R. Stockwell;José Pedro Friedmann Angeli;Hülya Bayir;Ashley I. Bush

  • Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer

    Charles L. Vogel;Melody A. Cobleigh;Debu Tripathy;John C. Gutheil

  • Cardiac Dysfunction in the Trastuzumab Clinical Trials Experience

    Andrew Seidman;Clifford Hudis;Mary Kathryn Pierri;Steven Shak

  • The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.

    Patrick Dumont;J. I-Ju Leu;Anthony C. Della Pietra;Donna L. George

  • p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

    Tongxiang Lin;Connie Chao;Shin'ichi Saito;Sharlyn J. Mazur

  • Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

    William H. Hoffman;Siham Biade;Jack T. Zilfou;Jiandong Chen

  • Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex

    J. I-Ju Leu;Patrick Dumont;Michael Hafey;Maureen E. Murphy

  • Analysis of p53-regulated gene expression patterns using oligonucleotide arrays

    Renbin Zhao;Kurt Gish;Maureen Murphy;Yuxin Yin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The HSP70 family and cancer

    Maureen E. Murphy

  • Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a

    Maureen Murphy;Jaimo Ahn;Kristen K. Walker;William H. Hoffman

  • A small molecule inhibitor of inducible heat shock protein 70.

    J. I-Ju Leu;Julia Pimkina;Amanda Frank;Maureen E. Murphy

  • BID regulation by p53 contributes to chemosensitivity

    Joanna K. Sax;Peiwen Fei;Maureen E. Murphy;Eric Bernhard

  • Fatty acid transport protein 2 reprograms neutrophils in cancer

    Filippo Veglia;Vladimir A. Tyurin;Maria Blasi;Alessandra De Leo

  • Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

    Constantinos Koumenis;Rodolfo Alarcon;Ester Hammond;Patrick Sutphin

  • The p53 family and programmed cell death.

    E C Pietsch;S M Sykes;S B McMahon;M E Murphy

  • An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model

    Matthew Jennis;Che-Pei Kung;Subhasree Basu;Anna Budina-Kolomets

  • Wild-type p53 negatively regulates the expression of a microtubule-associated protein.

    M Murphy;A Hinman;A J Levine

Frequent Co-Authors

Andrew V. Kossenkov
Andrew V. Kossenkov The Wistar Institute
Ashani T. Weeraratna
Ashani T. Weeraratna Johns Hopkins University
Arnold J. Levine
Arnold J. Levine Institute for Advanced Study
Wafik S. El-Deiry
Wafik S. El-Deiry Brown University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Monica Hollstein
Monica Hollstein University of Leeds
Sam W. Lee
Sam W. Lee Broad Institute
Sergio Lavandero
Sergio Lavandero University of Chile
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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