World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
111
Citations
67671
World Ranking
921
National Ranking
575

Research.com Recognitions

  • 2016 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2011 - Fellow of the American Society of Mechanical Engineers

Overview

Wei Gu is affiliated with Columbia University in the United States. Their research spans several domains within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology and biomedical engineering. The scientist's work also covers various subfields including cancer research, oncology, and endocrinology, diabetes, and metabolism.

The primary topics in Wei Gu's research include:

  • Advanced biosensing and bioanalysis techniques
  • RNA interference and gene delivery
  • Extracellular vesicles in disease
  • Cancer-related molecular pathways
  • Biosensors and analytical detection
  • RNA modifications and cancer
  • Acute ischemic stroke management

Wei Gu has published extensively in several prominent scientific journals, often contributing multiple papers to the following venues:

  • Small
  • Genes & Development
  • Advanced Functional Materials
  • Frontiers in Endocrinology
  • Small Methods

Recent papers authored or co-authored by Wei Gu include:

  • Spatiotemporally Controllable MicroRNA Imaging in Living Cells via a Near-Infrared Light-Activated Nanoprobe, 2020, ACS Applied Materials & Interfaces
  • Refining Cancer Management Using Integrated Liquid Biopsy, 2020, Theranostics
  • High-Fidelity Determination and Tracing of Small Extracellular Vesicle Cargoes, 2020, Small
  • Morphological, Physiological, and Secondary Metabolic Responses of Taraxacum officinale to Salt Stress, 2022, Plant Physiology and Biochemistry
  • Mutant p53 Regulates Survivin to Foster Lung Metastasis, 2021, Genes & Development

Frequent collaborators in Wei Gu's research include:

  • Yang Luo
  • Xiaopei Qiu
  • Xiaohong Chen
  • Xiaolin Hu
  • Liangliang Zhang

Wei Gu has been recognized with fellowships from notable scientific organizations, including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2016
  • Fellow of the American Society of Mechanical Engineers, 2011

Best Publications

  • Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

    Wei Gu;Robert G Roeder

  • Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

    Jianyuan Luo;Anatoly Y. Nikolaev;Shin ichiro Imai;Delin Chen

  • CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

    Weimin Wang;Michael Green;Jae Eun Choi;Miguel Gijón

  • Ferroptosis as a p53-mediated activity during tumour suppression

    Le Jiang;Ning Kon;Tongyuan Li;Shang–Jui Wang

  • Modes of p53 regulation.

    Jan Philipp Kruse;Wei Gu

  • Mammalian SIRT1 Represses Forkhead Transcription Factors

    Maria Carla Motta;Nullin Divecha;Madeleine Lemieux;Christopher Kamel

  • Ferroptosis as a target for protection against cardiomyopathy.

    Xuexian Fang;Hao Wang;Hao Wang;Dan Han;Enjun Xie

  • Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

    Muyang Li;Delin Chen;Ariel Shiloh;Jianyuan Luo

  • p53 ubiquitination: Mdm2 and beyond.

    Christopher L. Brooks;Wei Gu

  • Deacetylation of p53 modulates its effect on cell growth and apoptosis

    Jianyuan Luo;Fei Su;Delin Chen;Ariel Shiloh

  • Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2

    Muyang Li;Christopher L. Brooks;Foon Wu-Baer;Delin Chen

  • Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

    Christopher L Brooks;Wei Gu

  • Acetylation Is Indispensable for p53 Activation

    Yi Tang;Wenhui Zhao;Yue Chen;Yingming Zhao

  • Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

    Tongyuan Li;Ning Kon;Le Jiang;Minjia Tan

  • Cysteine depletion induces pancreatic tumor ferroptosis in mice.

    Michael A. Badgley;Daniel M. Kremer;H. Carlo Maurer;H. Carlo Maurer;Kathleen E. DelGiorno

  • Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

    Wei Gu;Jay W. Schneider;Jay W. Schneider;Gianluigi Condorelli;Gianluigi Condorelli;Sunjay Kaushal

  • Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

    Li Qiang;Liheng Wang;Ning Kon;Wenhui Zhao

  • Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis.

    Yi Tang;Jianyuan Luo;Wenzhu Zhang;Wei Gu

  • SIRT1 transgenic mice show phenotypes resembling calorie restriction.

    Laura Bordone;Dena Cohen;Ashley Robinson;Maria Carla Motta

  • Emerging Mechanisms and Disease Relevance of Ferroptosis.

    Brent R. Stockwell;Xuejun Jiang;Wei Gu

Frequent Co-Authors

Jun Qin
Jun Qin Baylor College of Medicine
Wei-Guo Zhu
Wei-Guo Zhu Shenzhen University
Yingming Zhao
Yingming Zhao University of Chicago
Yue Chen
Yue Chen University of Minnesota
Robert G. Roeder
Robert G. Roeder Rockefeller University
Riccardo Dalla-Favera
Riccardo Dalla-Favera Columbia University
Michael W. McBurney
Michael W. McBurney University of Ottawa
Domenico Accili
Domenico Accili Columbia University
Richard Baer
Richard Baer Columbia University

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