2016 - Fellow of the American Association for the Advancement of Science (AAAS)
2011 - Fellow of the American Society of Mechanical Engineers
Wei Gu spends much of his time researching Cell biology, Cancer research, Molecular biology, Transcription factor and Ubiquitin. His Cell biology research includes elements of Acetylation, DNA damage, Cell growth, Mdm2 and Ubiquitin ligase. Wei Gu combines subjects such as Carcinogenesis, Cell cycle checkpoint, Histone and Senescence with his study of Acetylation.
His DNA damage study integrates concerns from other disciplines, such as Apoptosis, Gene silencing and Sirtuin 1. His Molecular biology study combines topics from a wide range of disciplines, such as Coactivator, Transcription, Licensing factor, Pre-replication complex and DNA replication. His studies in Ubiquitin integrate themes in fields like Proto-Oncogene Proteins c-mdm2 and Nuclear protein.
Wei Gu mostly deals with Cell biology, Cancer research, Ubiquitin, Mdm2 and Acetylation. His work deals with themes such as DNA damage, Cell growth, Apoptosis, Molecular biology and Ubiquitin ligase, which intersect with Cell biology. His research integrates issues of Carcinogenesis, Signal transduction, Regulation of gene expression, Nuclear protein and Programmed cell death in his study of Cancer research.
He interconnects Gene knockdown and Phosphorylation in the investigation of issues within Ubiquitin. His research investigates the link between Mdm2 and topics such as In vivo that cross with problems in In vitro. The Acetylation study combines topics in areas such as Regulator, Histone, SUMO protein and Lysine.
Cell biology, Cancer research, Programmed cell death, Ubiquitin and Apoptosis are his primary areas of study. His Cell biology research includes themes of Carcinogenesis, Downregulation and upregulation, Cell growth and Mdm2. His Mdm2 research incorporates elements of Ubiquitin ligase and DNA damage.
Wei Gu has included themes like Cancer, Metastasis, In vitro, Acetylation and PI3K/AKT/mTOR pathway in his Cancer research study. His work on SLC7A11 is typically connected to Dexrazoxane as part of general Programmed cell death study, connecting several disciplines of science. His Ubiquitin research is multidisciplinary, relying on both Gene knockdown, DNA methyltransferase, Mutant protein, Transcription and DNA replication.
His primary areas of investigation include Cell biology, Programmed cell death, SLC7A11, Cancer research and Apoptosis. His Cell biology study incorporates themes from Histone, Ubiquitin, Gene and Cell growth. His Ubiquitin research is multidisciplinary, incorporating perspectives in Cell fate determination and Phosphorylation.
His Programmed cell death research is multidisciplinary, incorporating elements of Mitochondrion, Glutathione and Pharmacology. His SLC7A11 study combines topics in areas such as OTUB1, Interferon gamma, Immunotherapy, Cancer immunotherapy and Cytotoxic T cell. His research in Cancer research focuses on subjects like Motility, which are connected to Cancer cell.
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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
Wei Gu;Robert G Roeder.
Cell (1997)
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
Jianyuan Luo;Anatoly Y. Nikolaev;Shin ichiro Imai;Delin Chen.
Cell (2001)
Modes of p53 regulation.
Jan Philipp Kruse;Wei Gu.
Cell (2009)
Mammalian SIRT1 Represses Forkhead Transcription Factors
Maria Carla Motta;Nullin Divecha;Madeleine Lemieux;Christopher Kamel.
Cell (2004)
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang;Ning Kon;Tongyuan Li;Shang–Jui Wang.
Nature (2015)
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
Muyang Li;Delin Chen;Ariel Shiloh;Jianyuan Luo.
Nature (2002)
Mono- Versus Polyubiquitination: Differential Control of p53 Fate by Mdm2
Muyang Li;Christopher L. Brooks;Foon Wu-Baer;Delin Chen.
Science (2003)
p53 ubiquitination: Mdm2 and beyond.
Christopher L. Brooks;Wei Gu.
Molecular Cell (2006)
Deacetylation of p53 modulates its effect on cell growth and apoptosis
Jianyuan Luo;Fei Su;Delin Chen;Ariel Shiloh.
Nature (2000)
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
Christopher L Brooks;Wei Gu.
Current Opinion in Cell Biology (2003)
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