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Biology and Biochemistry
Greece
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
87
Citations
35516
World Ranking
2779
National Ranking
4

Medicine

D-Index
87
Citations
35772
World Ranking
13466
National Ranking
34

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2025 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2023 - Research.com Biology and Biochemistry in Greece Leader Award
  • 2022 - Research.com Biology and Biochemistry in Greece Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Vassilis G. Gorgoulis is affiliated with the National and Kapodistrian University of Athens in Greece. Their research spans multiple fields within the broad area of biochemistry, genetics, molecular biology, and medicine. With a total of 138 publications in Biochemistry, Genetics, and Molecular Biology and 126 in Medicine, their work covers a variety of subfields including molecular biology, physiology, immunology, infectious diseases, and cancer research.

Their main research topics include:

  • Telomeres, Telomerase, and Senescence
  • DNA Repair Mechanisms
  • Epigenetics and DNA Methylation
  • SARS-CoV-2 and COVID-19 Research
  • Advanced biosensing and bioanalysis techniques
  • COVID-19 Clinical Research Studies
  • Computational Drug Discovery Methods

Vassilis G. Gorgoulis has published numerous articles across several prominent venues. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Mechanisms of Ageing and Development
  • Cancers
  • Molecular Cell

Recent notable papers by Gorgoulis include the following:

  • "FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2", 2022, Nature
  • "Guidelines for minimal information on cellular senescence experimentation in vivo", 2024, Cell
  • "Algorithmic assessment of cellular senescence in experimental and clinical specimens", 2021, Nature Protocols
  • "Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression", 2021, Molecular Cell
  • "Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution", 2021, Cancer Discovery

The researcher's frequent collaborators include Konstantinos Evangelou, Nefeli Lagopati, Dimitris Veroutis, Sophia Havaki, and Angelos Papaspyropoulos. These collaborations highlight a network of contributors primarily focused on molecular biology and related biomedical fields.

Vassilis G. Gorgoulis holds membership in the European Molecular Biology Organization (EMBO), representing recognition within the molecular biology community.

Best Publications

  • Genomic instability — an evolving hallmark of cancer

    Simona Negrini;Vassilis G Gorgoulis;Thanos D Halazonetis

  • Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

    Vassilis G. Gorgoulis;Leandros-Vassilios F. Vassiliou;Panagiotis Karakaidos;Panayotis Zacharatos

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • Cellular Senescence: Defining a Path Forward

    Vassilis Gorgoulis;Peter D. Adams;Andrea Alimonti;Dorothy C. Bennett

  • An oncogene-induced DNA damage model for cancer development.

    Thanos D. Halazonetis;Vassilis G. Gorgoulis;Jiri Bartek

  • Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

    Yentram Huyen;Omar Zgheib;Omar Zgheib;Richard A. DiTullio;Richard A. DiTullio;Vassilis G. Gorgoulis;Vassilis G. Gorgoulis

  • Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

    Tomer Cooks;Ioannis S. Pateras;Ohad Tarcic;Hilla Solomon

  • Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

    Tomer Cooks;Ioannis S. Pateras;Lisa M. Jenkins;Keval M. Patel

  • Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

    Raffaella Di Micco;Gabriele Sulli;Miryana Dobreva;Michalis Liontos

  • Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues.

    EA Georgakopoulou;K Tsimaratou;K Evangelou;Marcos-PJ Fernandez

  • “High Risk” HPV Types Are Frequently Detected in Potentially Malignant and Malignant Oral Lesions, But Not in Normal Oral Mucosa

    Martha Bouda;Vassilis G Gorgoulis;Nikos G Kastrinakis;Athina Giannoudis

  • Ageing, Cellular Senescence and Neurodegenerative Disease.

    Marios Kritsilis;Sophia V Rizou;Paraskevi N Koutsoudaki;Konstantinos Evangelou

  • Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer.

    Alexandros Daskalos;Georgios Nikolaidis;George Xinarianos;Paraskevi Savvari

  • Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation.

    M Ogrunc;R Di Micco;M Liontos;L Bombardelli

  • Advances in the biology of oral cancer.

    P.K. Tsantoulis;N.G. Kastrinakis;A.D. Tourvas;G. Laskaris

  • Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

    Panagiotis Galanos;Konstantinos Vougas;David Walter;Alexander Polyzos

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress.

    Ioanna Andreadou;Fragiska Sigala;Efstathios K. Iliodromitis;Maria Papaefthimiou

  • Oncogene-induced senescence: the bright and dark side of the response.

    Vassilis G Gorgoulis;Thanos D Halazonetis

  • Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells.

    Lilach Weisz;Alexander Damalas;Michalis Liontos;Panagiotis Karakaidos

Frequent Co-Authors

Dimitris Kletsas
Dimitris Kletsas National Centre of Scientific Research Demokritos
Jiri Bartek
Jiri Bartek Karolinska Institute
Thanos D. Halazonetis
Thanos D. Halazonetis University of Geneva
Alexandros G. Georgakilas
Alexandros G. Georgakilas National Technical University of Athens
Paul A. Townsend
Paul A. Townsend University of Manchester
Athanasios G. Papavassiliou
Athanasios G. Papavassiliou National and Kapodistrian University of Athens
Petros P. Sfikakis
Petros P. Sfikakis National and Kapodistrian University of Athens
Aristides G. Eliopoulos
Aristides G. Eliopoulos National and Kapodistrian University of Athens
Moshe Oren
Moshe Oren Weizmann Institute of Science
Jirina Bartkova
Jirina Bartkova Karolinska Institute

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