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Biology and Biochemistry
Sweden
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
157
Citations
118793
World Ranking
136
National Ranking
3

Medicine

D-Index
156
Citations
119994
World Ranking
903
National Ranking
20

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2025 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jiri Bartek is affiliated with the Karolinska Institute in Sweden. Their research spans primarily the fields of Biochemistry, Genetics, and Molecular Biology, with a significant portion also covering Medicine. Within these broader areas, their work encompasses subfields such as Molecular Biology, Oncology, Cell Biology, Epidemiology, and Cancer Research.

The scientist's main research topics include:

  • DNA Repair Mechanisms
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Cancer-related Molecular Pathways
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation

Jiri Bartek has frequently published in the following scientific venues:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Death and Differentiation
  • Molecular Cell
  • Cancer Research

Notable recent papers include:

  • "Apoptotic cell death in disease-Current understanding of the NCCD 2023" (2023), published in Cell Death and Differentiation
  • "The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin" (2022), published in Nature Cell Biology
  • "AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity" (2021), published in Nature
  • "p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways" (2022), published in Cell Death and Differentiation
  • "Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution" (2021), published in Cancer Discovery

Jiri Bartek has collaborated extensively with several frequent co-authors, including Apolinar Maya-Mendoza, Martin Mistrík, Panagiotis Galanos, Dimitris C. Kanellis, and Zdeněk Hodný.

Among distinctions, Jiri Bartek is a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • The DNA-damage response in human biology and disease

    Stephen P. Jackson;Jiri Bartek

  • Cell-cycle checkpoints and cancer

    Michael B. Kastan;Jiri Bartek

  • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

    Jirina Bartkova;Zuzana Horejsí;Karen Koed;Alwin Krämer

  • The causes and consequences of genetic heterogeneity in cancer evolution.

    Rebecca A. Burrell;Nicholas McGranahan;Nicholas McGranahan;Jiri Bartek;Charles Swanton

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

  • An oncogene-induced DNA damage model for cancer development.

    Thanos D. Halazonetis;Vassilis G. Gorgoulis;Jiri Bartek

  • Chk1 and Chk2 kinases in checkpoint control and cancer.

    Jiri Bartek;Jiri Lukas

  • Human CtIP promotes DNA end resection

    Alessandro A. Sartori;Claudia Lukas;Julia Coates;Martin Mistrik

  • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.

    Jacob Falck;Niels Mailand;Randi G. Syljuåsen;Jiri Bartek

  • Increased expression of mutant forms of p53 oncogene in primary lung cancer.

    R Iggo;K Gatter;J Bartek;D Lane

  • ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

    Ali Jazayeri;Jacob Falck;Claudia Lukas;Jiri Bartek

  • RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

    Niels Mailand;Simon Bekker-Jensen;Helene Faustrup;Fredrik Melander

  • Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

    Jiri Lukas;David Parry;Louise Aagaard;David J. Mann

  • 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

    Peter Bouwman;Amal Mahmoud Aly;Jose M. Escandell;Mark Pieterse

  • RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

    Carsten Doil;Niels Mailand;Simon Bekker-Jensen;Patrice Menard

  • Rapid destruction of human Cdc25A in response to DNA damage.

    Niels Mailand;Jacob Falck;Claudia Lukas;Randi G. Syljuåsen

  • Checking on DNA damage in S phase

    Jiri Bartek;Claudia Lukas;Jiri Lukas

  • DNA damage checkpoints: from initiation to recovery or adaptation.

    Jiri Bartek;Jiri Lukas

  • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage

    Jirina Bartkova;Nousin Rezaei;Michalis Liontos;Panagiotis Karakaidos

Frequent Co-Authors

Jiri Lukas
Jiri Lukas University of Copenhagen
Jirina Bartkova
Jirina Bartkova Karolinska Institute
Claudia Lukas
Claudia Lukas University of Copenhagen
Niels Mailand
Niels Mailand University of Copenhagen
Claus Storgaard Sørensen
Claus Storgaard Sørensen University of Copenhagen
Simon Bekker-Jensen
Simon Bekker-Jensen University of Copenhagen
Markus Maeurer
Markus Maeurer Champalimaud Foundation
Charles Swanton
Charles Swanton The Francis Crick Institute
Thomas Helleday
Thomas Helleday Karolinska Institute
Ewa Rajpert-De Meyts
Ewa Rajpert-De Meyts University of Copenhagen

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