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D-Index & Metrics

Molecular Biology

D-Index
97
Citations
36543
World Ranking
590
National Ranking
51

Research.com Recognitions

  • 1998 - Member of Academia Europaea

Overview

Martin Eilers is affiliated with the University of Würzburg in Germany. Their research focuses primarily on the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions in Medicine. Subfields of study within their work include Molecular Biology, Oncology, Immunology, Cancer Research, and Cell Biology.

The scientist's research topics cover a range of specialized areas, such as:

  • Ubiquitin and proteasome pathways
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • Neuroblastoma Research and Treatments
  • Cancer-related gene regulation
  • Protein Degradation and Inhibitors

Martin Eilers has published extensively, with frequent contributions to several prominent venues. Some of the primary publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nature Communications
  • Genes & Development
  • Cancer Research

Their recent significant papers include:

  • "Target gene-independent functions of MYC oncoproteins" (2020) published in Nature Reviews Molecular Cell Biology
  • "MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling" (2022) published in Nature Communications
  • "Combined inhibition of Aurora-A and ATR kinases results in regression of MYCN-amplified neuroblastoma" (2021) published in Nature Cancer
  • "MYC multimers shield stalled replication forks from RNA polymerase" (2022) published in Nature
  • "Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination" (2021) published in Molecular Cell

Throughout their career, Martin Eilers has collaborated frequently with several researchers. Notable coauthors include:

  • Carsten P. Ade
  • Elmar Wolf
  • Peter Gallant
  • Christina Schülein-Völk
  • Gabriele Büchel

Recognition of their contributions to research is exemplified by their membership in Academia Europaea, awarded in 1998.

Best Publications

  • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.

    Marc van de Wetering;Elena Sancho;Cornelis Verweij;Wim de Lau

  • Transcriptional regulation and transformation by Myc proteins

    Sovana Adhikary;Martin Eilers

  • MYC regulates the antitumor immune response through CD47 and PD-L1

    Stephanie C. Casey;Ling Tong;Yulin Li;Rachel Do

  • Myc's broad reach.

    Martin Eilers;Robert N. Eisenman

  • Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria

    Martin Eilers;Gottfried Schatz

  • The MYC protein activates transcription of the alpha-prothymosin gene.

    M. Eilers;S. Schirm;J. M. Bishop

  • Repression of p15INK4b expression by Myc through association with Miz-1.

    Peter Staller;Karen Peukert;Astrid Kiermaier;Joan Seoane

  • Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

    Caroline Bouchard;Katja Thieke;Antje Maier;Rainer Saffrich

  • TGFbeta Influences Myc, Miz-1 and Smad to Control the CDK Inhibitor p15INK4b

    Joan Seoane;Celio Pouponnot;Peter Staller;Manuela Schader

  • Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

    M Eilers;D Picard;K R Yamamoto;J M Bishop

  • Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

    Tobias Otto;Sebastian Horn;Markus Brockmann;Ursula Eilers

  • The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.

    Sovana Adhikary;Federica Marinoni;Andreas Hock;Esther Hulleman

  • The ubiquitin-specific protease USP28 is required for MYC stability

    Nikita Popov;Michael Wanzel;Mandy Madiredjo;Dong Zhang

  • Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

    Susanne Walz;Francesca Lorenzin;Jennifer Morton;Katrin E. Wiese

  • N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

    Etienne Dardenne;Himisha Beltran;Matteo Benelli;Kaitlyn Gayvert

  • An alternative pathway for gene regulation by Myc.

    Karen Peukert;Peter Staller;Andreas Schneider;Gordon Carmichael

  • Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma

    Ximena Bonilla;Laurent Parmentier;Bryan King;Fedor Bezrukov;Fedor Bezrukov

  • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

    Caroline Bouchard;Oliver Dittrich;Astrid Kiermaier;Karen Dohmann

  • Differential modulation of cyclin gene expression by MYC

    Pidder Jansen-Durr;Albrecht Meichle;Philipp Steiner;Michele Pagano

  • Negative Regulation of the Mammalian UV Response by Myc through Association with Miz-1

    Steffi Herold;Michael Wanzel;Vincent Beuger;Carsten Frohme

Frequent Co-Authors

Lars Zender
Lars Zender German Cancer Research Center
Andreas Rosenwald
Andreas Rosenwald University of Würzburg
Tarik Möröy
Tarik Möröy University of Montreal
Tero Aittokallio
Tero Aittokallio University of Helsinki
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Gottfried Schatz
Gottfried Schatz University of Basel
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Richard Bayliss
Richard Bayliss University of Leeds
Owen J. Sansom
Owen J. Sansom University of Glasgow
Johannes H. Schulte
Johannes H. Schulte Charité - University Medicine Berlin

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