World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
119
Citations
88098
World Ranking
654
National Ranking
414

Medicine

D-Index
119
Citations
88135
World Ranking
3805
National Ranking
2087

Overview

Chi V. Dang is primarily affiliated with the University of Pennsylvania in the United States. Their research spans multiple disciplines, notably within biochemistry, genetics, molecular biology, and medicine. The scientist's work is focused on several subfields including molecular biology, cancer research, oncology, immunology, and pathology and forensic medicine.

The main topics explored in their research include:

  • Cancer, Hypoxia, and Metabolism
  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • Neuroblastoma Research and Treatments
  • Genetic factors in colorectal cancer
  • Circadian rhythm and melatonin
  • Mitochondrial Function and Pathology

The scientist has published extensively, with frequent publications in venues such as Cancer Research (13 publications), bioRxiv (Cold Spring Harbor Laboratory) with 7 publications, Cell Reports, Proceedings of the National Academy of Sciences, and SSRN Electronic Journal, each having two publications.

Recent papers by Chi V. Dang showcase a focus on cancer metabolism, immune response, and targeted therapies. Examples include:

  • Targeting cancer metabolism in the era of precision oncology, 2021, Nature Reviews Drug Discovery
  • The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer, 2022, Science Immunology
  • Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma, 2021, Nature Cancer
  • Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy, 2020, Cell Reports
  • Time-of-day specificity of anticancer drugs may be mediated by circadian regulation of the cell cycle, 2021, Science Advances

In collaboration, Chi V. Dang frequently works with a core group of co-authors who have contributed substantially across many projects. These collaborators include Adam J. Wolpaw, Kenneth C. Anderson, Lewis C. Cantley, Riccardo Dalla-Favera, and Luis A. Díaz, each maintaining significant joint publication counts.

Best Publications

  • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

    Jung Whan Kim;Irina Tchernyshyov;Gregg L. Semenza;Chi V. Dang

  • Otto Warburg's contributions to current concepts of cancer metabolism

    Willem H. Koppenol;Patricia L. Bounds;Chi V. Dang

  • c-Myc-regulated microRNAs modulate E2F1 expression.

    Kathryn A. O'Donnell;Erik A. Wentzel;Karen I. Zeller;Chi V. Dang

  • MYC on the Path to Cancer

    Chi V. Dang

  • c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.

    Ping Gao;Irina Tchernyshyov;Tsung Cheng Chang;Yun Sil Lee

  • c-Myc target genes involved in cell growth, apoptosis, and metabolism

    Chi V. Dang

  • From Krebs to clinic: glutamine metabolism to cancer therapy.

    Brian J. Altman;Zachary E. Stine;Chi V. Dang

  • Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

    Eric V. Dang;Joseph Barbi;Huang Yu Yang;Huang Yu Yang;Dilini Jinasena

  • Widespread microRNA repression by Myc contributes to tumorigenesis.

    Tsung Cheng Chang;Duonan Yu;Yun Sil Lee;Erik A. Wentzel

  • Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

    Anne Le;Charles R. Cooper;Arvin M. Gouw;Ramani Dinavahi

  • Cancer's Molecular Sweet Tooth and the Warburg Effect

    Jung Whan Kim;Chi V. Dang

  • Oncogenic alterations of metabolism.

    Chi V Dang;Gregg L Semenza

  • HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells

    Ryo Fukuda;Huafeng Zhang;Jung whan Kim;Larissa Shimoda

  • The c-Myc target gene network.

    Chi V. Dang;Kathryn A. O’Donnell;Karen I. Zeller;Tam Nguyen

  • Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

    Suraj Peri;Suraj Peri;J. Daniel Navarro;J. Daniel Navarro;Ramars Amanchy;Troels Z. Kristiansen;Troels Z. Kristiansen

  • c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth

    Hyunsuk Shim;Christine Dolde;Brian C. Lewis;Chyi Sun Wu

  • Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

    Anne Le;Andrew N. Lane;Max Hamaker;Sminu Bose

  • Links between metabolism and cancer

    Chi V. Dang

  • c-MYC-regulated micro RNAs modulate E2F1 expression

    Kathryn A. O'Donnell;Erik A. Wentzel;Karen I. Zeller;Chi V. Dang

  • Erratum: Otto Warburg's contributions to current concepts of cancer metabolism

    Willem H. Koppenol;Patricia L. Bounds;Chi V. Dang

Frequent Co-Authors

Gregg L. Semenza
Gregg L. Semenza Johns Hopkins University School of Medicine
Gregory J. Kato
Gregory J. Kato CSL Behring
John B. Hogenesch
John B. Hogenesch Cincinnati Children's Hospital Medical Center
Anirban Maitra
Anirban Maitra The University of Texas MD Anderson Cancer Center
Angelo M. De Marzo
Angelo M. De Marzo Johns Hopkins University School of Medicine
Lin Zhang
Lin Zhang University of Pennsylvania
Linzhao Cheng
Linzhao Cheng Chinese Academy of Sciences
Joshua T. Mendell
Joshua T. Mendell The University of Texas Southwestern Medical Center
Joshua D. Rabinowitz
Joshua D. Rabinowitz Princeton University
Huafeng Zhang
Huafeng Zhang University of Science and Technology of China

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