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Biology and Biochemistry

D-Index
65
Citations
58337
World Ranking
8907
National Ranking
3956

Overview

Joshua T. Mendell is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily falls within the broader field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cancer Research, Pulmonary and Respiratory Medicine, Immunology, and Oncology as key subfields.

The scientist's work extensively explores various topics, including:

  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Prostate Cancer Treatment and Research

Joshua T. Mendell has published in several prominent venues, with multiple papers appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genes & Development
  • Molecular Cell
  • Cell Reports
  • Cancer Research

Frequent co-authors collaborating with this scientist include:

  • He Zhang
  • Jaeil Han
  • Benjamin T. Jones
  • Bret M. Evers
  • Asha Acharya

Significant recent publications include:

  • "Long non-coding RNAs: definitions, functions, challenges and recommendations" (2023), Nature Reviews Molecular Cell Biology
  • "NORAD-induced Pumilio phase separation is required for genome stability" (2021), Nature
  • "A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming" (2020), Science
  • "Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation" (2020), Cancer Cell
  • "Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination" (2020), Molecular Cell

Best Publications

  • StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

    Mihaela Pertea;Geo M. Pertea;Corina M. Antonescu;Tsung Cheng Chang

  • c-Myc-regulated microRNAs modulate E2F1 expression.

    Kathryn A. O'Donnell;Erik A. Wentzel;Karen I. Zeller;Chi V. Dang

  • Functional Classification and Experimental Dissection of Long Noncoding RNAs

    Florian Kopp;Joshua T. Mendell

  • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

    Tsung Cheng Chang;Erik A. Wentzel;Oliver A. Kent;Kalyani Ramachandran

  • c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.

    Ping Gao;Irina Tchernyshyov;Tsung Cheng Chang;Yun Sil Lee

  • Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

    Janaiah Kota;Raghu R. Chivukula;Kathryn A. O'Donnell;Erik A. Wentzel

  • MicroRNAs in Stress Signaling and Human Disease

    Joshua T. Mendell;Eric N. Olson

  • Widespread microRNA repression by Myc contributes to tumorigenesis.

    Tsung Cheng Chang;Duonan Yu;Yun Sil Lee;Erik A. Wentzel

  • MicroRNAs in cell proliferation, cell death, and tumorigenesis.

    H. W. Hwang;J. T. Mendell

  • miRiad roles for the miR-17-92 cluster in development and disease

    Joshua T. Mendell

  • Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

    Michael Dews;Asal Homayouni;Duonan Yu;Danielle Murphy

  • MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

    Tamia A. Harris;Munekazu Yamakuchi;Marcella Ferlito;Joshua T. Mendell

  • Involvement of Human Micro-RNA in Growth and Response to Chemotherapy in Human Cholangiocarcinoma Cell Lines

    Fanyin Meng;Roger Henson;Molly Lang;Hania Wehbe

  • Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise.

    Joshua T. Mendell;Neda A. Sharifi;Jennifer L. Meyers;Francisco Martinez-Murillo

  • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

    Shu Hao Hsu;Bo Wang;Janaiah Kota;Jianhua Yu

  • A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes.

    O. A. Kent;J. T. Mendell

  • Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.

    Sungyul Lee;Florian Kopp;Tsung Cheng Chang;Anupama Sataluri

  • A hexanucleotide element directs microRNA nuclear import.

    Hun Way Hwang;Erik A. Wentzel;Joshua T. Mendell

  • microRNAs in Vertebrate Physiology and Human Disease

    Tsung Cheng Chang;Joshua T. Mendell

  • Abstract #LB-186: c-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism

    Ping Gao;Irina Tchernyshyov;Tsung-Cheng Chang;Yun-Sil Lee

Frequent Co-Authors

Zarife Sahenk
Zarife Sahenk Nationwide Children's Hospital
Jerry R. Mendell
Jerry R. Mendell The Ohio State University
Anirban Maitra
Anirban Maitra The University of Texas MD Anderson Cancer Center
Yang Xie
Yang Xie The University of Texas Southwestern Medical Center
Harry C. Dietz
Harry C. Dietz Johns Hopkins University School of Medicine
Chi V. Dang
Chi V. Dang University of Pennsylvania
Hongtao Yu
Hongtao Yu The University of Texas Southwestern Medical Center
Michael Goggins
Michael Goggins Johns Hopkins University
George A. Marzluf
George A. Marzluf The Ohio State University
Dan E. Arking
Dan E. Arking Johns Hopkins University School of Medicine

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