D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 41 Citations 7,991 89 World Ranking 17498 National Ranking 808

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Bacteria

His primary areas of investigation include Mycobacterium tuberculosis, Microbiology, Virulence, Mutant and Gene. The various areas that Christophe Guilhot examines in his Mycobacterium tuberculosis study include Mutagenesis and Genetics. His Microbiology research is multidisciplinary, incorporating elements of Mycolic acid, Cell envelope and Bacteria.

His Virulence research includes themes of Locus and Virology. His Mutant study combines topics in areas such as Cell membrane, Membrane fluidity, Cell biology, Phagosome acidification and Membrane lipids. Gene is closely attributed to Molecular biology in his work.

His most cited work include:

  • Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis (554 citations)
  • Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis (424 citations)
  • Analysis of the Phthiocerol Dimycocerosate Locus ofMycobacterium tuberculosis EVIDENCE THAT THIS LIPID IS INVOLVED IN THE CELL WALL PERMEABILITY BARRIER (312 citations)

What are the main themes of his work throughout his whole career to date?

Christophe Guilhot spends much of his time researching Mycobacterium tuberculosis, Microbiology, Virulence, Mutant and Gene. He interconnects Pathogen, Phagocytosis, Cell biology, Polyketide and Macrophage in the investigation of issues within Mycobacterium tuberculosis. His Microbiology study incorporates themes from Glycolipid, Mycobacterium bovis, Cell envelope and Bacteria.

The study incorporates disciplines such as Virology, Secretion, Point mutation, Locus and Human pathogen in addition to Virulence. The concepts of his Mutant study are interwoven with issues in Molecular biology, Mycobacterium and Mycobacterium smegmatis. His work in Gene covers topics such as Tuberculosis vaccines which are related to areas like Genetically engineered.

He most often published in these fields:

  • Mycobacterium tuberculosis (82.61%)
  • Microbiology (70.65%)
  • Virulence (54.35%)

What were the highlights of his more recent work (between 2016-2020)?

  • Mycobacterium tuberculosis (82.61%)
  • Virulence (54.35%)
  • Cell biology (11.96%)

In recent papers he was focusing on the following fields of study:

Christophe Guilhot mainly focuses on Mycobacterium tuberculosis, Virulence, Cell biology, Virulence factor and Mycobacterium. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Pathogen, Microbiology and Polyketide. His Microbiology study combines topics from a wide range of disciplines, such as Secretion, ESAT-6, Lipoarabinomannan and Bacterial outer membrane.

Christophe Guilhot regularly links together related areas like Mutant in his Virulence studies. In his study, which falls under the umbrella issue of Mutant, Gene and Homologous recombination is strongly linked to Paratuberculosis. Christophe Guilhot combines subjects such as Receptor and Macrophage with his study of Cell biology.

Between 2016 and 2020, his most popular works were:

  • ESX-1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis. (89 citations)
  • The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages (22 citations)
  • Mycobacterial Phenolic Glycolipids Selectively Disable TRIF-Dependent TLR4 Signaling in Macrophages. (13 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Bacteria

Christophe Guilhot mainly investigates Mycobacterium tuberculosis, Secretion, Cell biology, Microbiology and Virulence. His biological study spans a wide range of topics, including Virulence factor and Pathogen. His studies in Secretion integrate themes in fields like Receptor, Internalization, Lipid droplet and Intracellular.

In general Cell biology, his work in Signal transduction and TLR4 is often linked to TRIF and Complement receptor linking many areas of study. His Microbiology research includes elements of TLR2, Mutant and Lipoarabinomannan. His work deals with themes such as Bacterial outer membrane, Mycobacterium bovis, ESAT-6 and Mycobacterium, which intersect with Virulence.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis

Luis Reinaldo Camacho;Danielle Ensergueix;Esther Perez;Brigitte Gicquel.
Molecular Microbiology (1999)

757 Citations

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

Vladimir Pelicic;Mary Jackson;Jean Marc Reyrat;William R. Jacobs.
Proceedings of the National Academy of Sciences of the United States of America (1997)

548 Citations

An essential role for phoP in Mycobacterium tuberculosis virulence.

Esther Pérez;Sofía Samper;Yann Bordas;Christophe Guilhot.
Molecular Microbiology (2001)

444 Citations

A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

Damien Portevin;Célia de Sousa-D'Auria;Christine Houssin;Christine Grimaldi.
Proceedings of the National Academy of Sciences of the United States of America (2004)

431 Citations

Analysis of the Phthiocerol Dimycocerosate Locus ofMycobacterium tuberculosis EVIDENCE THAT THIS LIPID IS INVOLVED IN THE CELL WALL PERMEABILITY BARRIER

Luis R. Camacho;Patricia Constant;Catherine Raynaud;Marie Antoinette Lanéelle.
Journal of Biological Chemistry (2001)

429 Citations

Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope.

Mary Jackson;Catherine Raynaud;Marie‐Antoinette Lanéelle;Christophe Guilhot.
Molecular Microbiology (1999)

338 Citations

Phthiocerol dimycocerosates of M. tuberculosis participate in macrophage invasion by inducing changes in the organization of plasma membrane lipids.

Catherine Astarie-Dequeker;Laurent Le Guyader;Wladimir Malaga;Fam-Ky Seaphanh.
PLOS Pathogens (2009)

270 Citations

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis.

Catherine Raynaud;Christophe Guilhot;Jean Rauzier;Yann Bordat.
Molecular Microbiology (2002)

249 Citations

Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials.

Ainhoa Arbues;Ainhoa Arbues;Juan I. Aguilo;Juan I. Aguilo;Jesus Gonzalo-Asensio;Jesus Gonzalo-Asensio;Dessislava Marinova;Dessislava Marinova.
Vaccine (2013)

249 Citations

Persistence and Protective Efficacy of a Mycobacterium tuberculosis Auxotroph Vaccine

Mary Jackson;Susan W. Phalen;Micheline Lagranderie;Danielle Ensergueix.
Infection and Immunity (1999)

228 Citations

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