His primary areas of investigation include Mycobacterium tuberculosis, Microbiology, Virulence, Mutant and Gene. The various areas that Christophe Guilhot examines in his Mycobacterium tuberculosis study include Mutagenesis and Genetics. His Microbiology research is multidisciplinary, incorporating elements of Mycolic acid, Cell envelope and Bacteria.
His Virulence research includes themes of Locus and Virology. His Mutant study combines topics in areas such as Cell membrane, Membrane fluidity, Cell biology, Phagosome acidification and Membrane lipids. Gene is closely attributed to Molecular biology in his work.
Christophe Guilhot spends much of his time researching Mycobacterium tuberculosis, Microbiology, Virulence, Mutant and Gene. He interconnects Pathogen, Phagocytosis, Cell biology, Polyketide and Macrophage in the investigation of issues within Mycobacterium tuberculosis. His Microbiology study incorporates themes from Glycolipid, Mycobacterium bovis, Cell envelope and Bacteria.
The study incorporates disciplines such as Virology, Secretion, Point mutation, Locus and Human pathogen in addition to Virulence. The concepts of his Mutant study are interwoven with issues in Molecular biology, Mycobacterium and Mycobacterium smegmatis. His work in Gene covers topics such as Tuberculosis vaccines which are related to areas like Genetically engineered.
Christophe Guilhot mainly focuses on Mycobacterium tuberculosis, Virulence, Cell biology, Virulence factor and Mycobacterium. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Pathogen, Microbiology and Polyketide. His Microbiology study combines topics from a wide range of disciplines, such as Secretion, ESAT-6, Lipoarabinomannan and Bacterial outer membrane.
Christophe Guilhot regularly links together related areas like Mutant in his Virulence studies. In his study, which falls under the umbrella issue of Mutant, Gene and Homologous recombination is strongly linked to Paratuberculosis. Christophe Guilhot combines subjects such as Receptor and Macrophage with his study of Cell biology.
Christophe Guilhot mainly investigates Mycobacterium tuberculosis, Secretion, Cell biology, Microbiology and Virulence. His biological study spans a wide range of topics, including Virulence factor and Pathogen. His studies in Secretion integrate themes in fields like Receptor, Internalization, Lipid droplet and Intracellular.
In general Cell biology, his work in Signal transduction and TLR4 is often linked to TRIF and Complement receptor linking many areas of study. His Microbiology research includes elements of TLR2, Mutant and Lipoarabinomannan. His work deals with themes such as Bacterial outer membrane, Mycobacterium bovis, ESAT-6 and Mycobacterium, which intersect with Virulence.
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Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature‐tagged transposon mutagenesis
Luis Reinaldo Camacho;Danielle Ensergueix;Esther Perez;Brigitte Gicquel.
Molecular Microbiology (1999)
Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis
Vladimir Pelicic;Mary Jackson;Jean Marc Reyrat;William R. Jacobs.
Proceedings of the National Academy of Sciences of the United States of America (1997)
An essential role for phoP in Mycobacterium tuberculosis virulence.
Esther Pérez;Sofía Samper;Yann Bordas;Christophe Guilhot.
Molecular Microbiology (2001)
A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms
Damien Portevin;Célia de Sousa-D'Auria;Christine Houssin;Christine Grimaldi.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Analysis of the Phthiocerol Dimycocerosate Locus ofMycobacterium tuberculosis EVIDENCE THAT THIS LIPID IS INVOLVED IN THE CELL WALL PERMEABILITY BARRIER
Luis R. Camacho;Patricia Constant;Catherine Raynaud;Marie Antoinette Lanéelle.
Journal of Biological Chemistry (2001)
Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope.
Mary Jackson;Catherine Raynaud;Marie‐Antoinette Lanéelle;Christophe Guilhot.
Molecular Microbiology (1999)
Phthiocerol dimycocerosates of M. tuberculosis participate in macrophage invasion by inducing changes in the organization of plasma membrane lipids.
Catherine Astarie-Dequeker;Laurent Le Guyader;Wladimir Malaga;Fam-Ky Seaphanh.
PLOS Pathogens (2009)
Phospholipases C are involved in the virulence of Mycobacterium tuberculosis.
Catherine Raynaud;Christophe Guilhot;Jean Rauzier;Yann Bordat.
Molecular Microbiology (2002)
Construction, characterization and preclinical evaluation of MTBVAC, the first live-attenuated M. tuberculosis-based vaccine to enter clinical trials.
Ainhoa Arbues;Ainhoa Arbues;Juan I. Aguilo;Juan I. Aguilo;Jesus Gonzalo-Asensio;Jesus Gonzalo-Asensio;Dessislava Marinova;Dessislava Marinova.
Persistence and Protective Efficacy of a Mycobacterium tuberculosis Auxotroph Vaccine
Mary Jackson;Susan W. Phalen;Micheline Lagranderie;Danielle Ensergueix.
Infection and Immunity (1999)
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