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Microbiology

D-Index
87
Citations
24610
World Ranking
807
National Ranking
44

Overview

Mamadou Daffé is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Infectious Diseases, Molecular Biology, Ecology, Surgery, and Microbiology. Their work is situated at the intersection of several scientific domains including tuberculosis research, bacteriophage biology, and microbial infections.

Their recent publications cover a range of topics related to infectious diseases and microbial interactions. Notable papers include:

  • "Mycobacterium tuberculosis bloodstream infection prevalence, diagnosis, and mortality risk in seriously ill adults with HIV: a systematic review and meta-analysis of individual patient data," 2020, The Lancet Infectious Diseases
  • "FX11 limits Mycobacterium tuberculosis growth and potentiates bactericidal activity of isoniazid through host-directed activity," 2020, Disease Models & Mechanisms
  • "Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection," 2021, Viruses
  • "Role of Premycofactocin Synthase in Growth, Microaerophilic Adaptation, and Metabolism of Mycobacterium tuberculosis," 2021, mBio
  • "ESX-5-targeted export of ESAT-6 in BCG combines enhanced immunogenicity & efficacy against murine tuberculosis with low virulence and reduced persistence," 2021, Vaccine

Daffé has collaborated frequently with several researchers, including Martin Witzenrath, Geraldine Nouailles, Stefan H. E. Kaufmann, Sandra-Maria Wienhold, and Imke H. E. Korf. These collaborations have contributed to work published in various scientific venues.

Their publications have appeared multiple times in venues such as Pneumologie, International Journal of Molecular Sciences, The Lancet Infectious Diseases, Disease Models & Mechanisms, and Viruses. This range reflects an interdisciplinary approach that bridges clinical and molecular research.

Their main research topics include:

  • Tuberculosis Research and Epidemiology
  • Bacteriophages and microbial interactions
  • Microbial infections and disease research
  • Diagnosis and treatment of tuberculosis
  • Biochemical and Molecular Research
  • Mycobacterium research and diagnosis
  • Immune responses and vaccinations

Best Publications

  • The envelope layers of mycobacteria with reference to their pathogenicity.

    Mamadou Daffé;Philip Draper

  • Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

    Pascale Peyron;Julien Vaubourgeix;Julien Vaubourgeix;Yannick Poquet;Yannick Poquet;Florence Levillain;Florence Levillain

  • Mycolic acids: structures, biosynthesis, and beyond.

    Hedia Marrakchi;Hedia Marrakchi;Marie-Antoinette Lanéelle;Marie-Antoinette Lanéelle;Mamadou Daffé;Mamadou Daffé

  • Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State

    Benoît Zuber;Mohamed Chami;Christine Houssin;Christine Houssin;Jacques Dubochet

  • A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

    Damien Portevin;Célia de Sousa-D'Auria;Christine Houssin;Christine Grimaldi

  • The Mycobacterium tuberculosis PhoPR two‐component system regulates genes essential for virulence and complex lipid biosynthesis

    Shaun B. Walters;Eugenie Dubnau;Irina Kolesnikova;Francoise Laval

  • Analysis of the Phthiocerol Dimycocerosate Locus ofMycobacterium tuberculosis EVIDENCE THAT THIS LIPID IS INVOLVED IN THE CELL WALL PERMEABILITY BARRIER

    Luis R. Camacho;Patricia Constant;Catherine Raynaud;Marie Antoinette Lanéelle

  • Non Mycobacterial Virulence Genes in the Genome of the Emerging Pathogen Mycobacterium abscessus

    Fabienne Ripoll;Sophie Pasek;Chantal Schenowitz;Carole Dossat

  • Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer

    Timothy Paul Stinear;Torsten Seemann;Sacha James Pidot;Wafa Frigui

  • Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice.

    Eugenie Dubnau;John Chan;Catherine Raynaud;Vellore P. Mohan

  • AhR sensing of bacterial pigments regulates antibacterial defence

    Pedro Moura-Alves;Kellen Faé;Erica Houthuys;Anca Dorhoi

  • Predominant structural features of the cell wall arabinogalactan of Mycobacterium tuberculosis as revealed through characterization of oligoglycosyl alditol fragments by gas chromatography/mass spectrometry and by 1H and 13C NMR analyses.

    M Daffe;P J Brennan;M McNeil

  • Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins.

    Musa Sani;Edith N G Houben;Jeroen Geurtsen;Jason Pierson

  • Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species.

    A. Ortalo-Magne;A. Lemassu;M.-A. Laneelle;F. Bardou

  • Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope.

    Mary Jackson;Catherine Raynaud;Marie‐Antoinette Lanéelle;Christophe Guilhot

  • Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls.

    M McNeil;M Daffe;P J Brennan

  • Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene.

    Patricia Constant;Esther Perez;Wladimir Malaga;Marie-Antoinette Lanéelle

  • Location of the mycolyl ester substituents in the cell walls of mycobacteria.

    M McNeil;M Daffe;P J Brennan

  • Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane.

    Laura Chiaradia;Cyril Lefebvre;Julien Parra;Julien Marcoux

  • The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis.

    Jesús Gonzalo Asensio;Catarina Maia;Nadia L. Ferrer;Nathalie Barilone

  • Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy

    Lian-Yong Gao;Francoise Laval;Elise H. Lawson;Richard K. Groger

  • Structure of the cell envelope of corynebacteria: importance of the non-covalently bound lipids in the formation of the cell wall permeability barrier and fracture plane.

    Virginie Puech;Mohamed Chami;Mohamed Chami;Anne Lemassu;Marie Antoinette Lanéelle

Frequent Co-Authors

Christophe Guilhot
Christophe Guilhot Paul Sabatier University
Lionel Mourey
Lionel Mourey Federal University of Toulouse Midi-Pyrénées
Mary Jackson
Mary Jackson Colorado State University
Brigitte Gicquel
Brigitte Gicquel Institut Pasteur
Roland Brosch
Roland Brosch Institut Pasteur
Isabelle Maridonneau-Parini
Isabelle Maridonneau-Parini Federal University of Toulouse Midi-Pyrénées
Jean-Louis Gaillard
Jean-Louis Gaillard Hôpital Ambroise-Paré
Olivier Neyrolles
Olivier Neyrolles Paul Sabatier University
Roland Benz
Roland Benz Jacobs University
Tanya Parish
Tanya Parish Seattle Children's Hospital

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