Her primary scientific interests are in Immunology, Microbiology, Dendritic cell, Mycobacterium tuberculosis and Mycobacterium bovis. When carried out as part of a general Immunology research project, her work on T cell, Tumor antigen and Antigen is frequently linked to work in Lymph, therefore connecting diverse disciplines of study. Her studies deal with areas such as Virulence and Virology as well as Microbiology.
Her Virology research is multidisciplinary, relying on both Buruli ulcer, Mycobacterium ulcerans and Mycolactone. Her Dendritic cell research entails a greater understanding of Immune system. Her Mycobacterium bovis study integrates concerns from other disciplines, such as ESAT-6 and Immunogenicity.
Her scientific interests lie mostly in Mycolactone, Immunology, Microbiology, Buruli ulcer and Mycobacterium ulcerans. Her Mycolactone research includes elements of In vitro, Toxin, Total synthesis, Stereochemistry and Cell biology. Immune system, Inflammation, Dendritic cell, Chemokine and Cytokine are subfields of Immunology in which her conducts study.
Her studies in Dendritic cell integrate themes in fields like Interleukin 12, Antigen presentation, CD40 and Antigen-presenting cell. Her work deals with themes such as Mycobacterium bovis, Mycobacterium tuberculosis, Virology, Immunogenicity and Virulence, which intersect with Microbiology. Her work deals with themes such as Mycobacterium tuberculosis complex and Secretion, which intersect with Mycobacterium bovis.
Caroline Demangel mainly investigates Mycolactone, Cell biology, Buruli ulcer, Secretory protein and Endoplasmic reticulum. Her Mycolactone research is multidisciplinary, relying on both Toxin, Microbiology and Immunization, Antigen. Her studies deal with areas such as Lipid droplet and Virulence as well as Microbiology.
The various areas that Caroline Demangel examines in her Cell biology study include Cell cycle and Downregulation and upregulation. Her work carried out in the field of Buruli ulcer brings together such families of science as Cytotoxic T cell, Antibody, Phage display and Virology. Her research investigates the connection with Cytotoxic T cell and areas like Blockade which intersect with concerns in Immunology.
The scientist’s investigation covers issues in Secretory protein, Sec61, Cell biology, Endoplasmic reticulum and Mycolactone. Her biological study spans a wide range of topics, including Unfolded protein response and ATF4. Her Unfolded protein response study integrates concerns from other disciplines, such as Signal peptide, Transmembrane domain and Transmembrane protein.
Many of her studies on ATF4 involve topics that are commonly interrelated, such as Buruli ulcer. The study incorporates disciplines such as Transport protein, Biogenesis, Protein subunit and Drug discovery in addition to Translocon.
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TNF Regulates Chemokine Induction Essential for Cell Recruitment, Granuloma Formation, and Clearance of Mycobacterial Infection
Daniel R. Roach;Andrew G. D. Bean;Caroline Demangel.
Journal of Immunology (2002)
Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.
Alexander S. Pym;Alexander S. Pym;Priscille Brodin;Laleh Majlessi;Roland Brosch.
Nature Medicine (2003)
Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis
Roselyne Binétruy-Tournaire;Caroline Demangel;Bernard Malavaud;Roger Vassy.
The EMBO Journal (2000)
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria
Diane Houben;Caroline Demangel;Jakko Van Ingen;Jorge Perez.
Cellular Microbiology (2012)
Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence
Priscille Brodin;Laleh Majlessi;Laurent Marsollier;Marien I. de Jonge.
Infection and Immunity (2006)
Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapy.
Christina L. van Broekhoven;Christopher R. Parish;Caroline Demangel;Warwick J. Britton.
Cancer Research (2004)
Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures
Serge Mostowy;Serge Mostowy;Serge Mostowy;Matteo Bonazzi;Matteo Bonazzi;Matteo Bonazzi;Mélanie Anne Hamon;Mélanie Anne Hamon;Mélanie Anne Hamon;To Nam Tham;To Nam Tham;To Nam Tham.
Cell Host & Microbe (2010)
Autocrine IL‐10 impairs dendritic cell (DC)‐derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL‐12 production
Caroline Demangel;Patrick Bertolino;Warwick J. Britton;Warwick J. Britton.
European Journal of Immunology (2002)
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans.
Caroline Demangel;Timothy Paul Stinear;Stewart T Cole.
Nature Reviews Microbiology (2009)
Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer
Claire Biot;Claire Biot;Claire Biot;Cyrill A. Rentsch;Cyrill A. Rentsch;Cyrill A. Rentsch;Joel R. Gsponer;Joel R. Gsponer;Joel R. Gsponer;Frédéric D. Birkhäuser.
Science Translational Medicine (2012)
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