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Biology and Biochemistry

D-Index
57
Citations
9051
World Ranking
14071
National Ranking
539

Overview

Georges Bismuth is affiliated with Université Paris Cité in France and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work spans molecular biology, immunology, organic chemistry, oncology, and electrical and electronic engineering, reflecting interdisciplinary approaches in life sciences and technology.

The scientist's main research topics focus on glycosylation and glycoproteins, galectins and cancer biology, carbohydrate chemistry and synthesis, CAR-T cell therapy, viral infectious diseases, gene expression in insects, silicon carbide semiconductor technologies, and aspects of Cambodian history and society.

Recent research outputs include:

  • Lipopolysaccharide Induces GFAT2 Expression to Promote O-Linked β- N-Acetylglucosaminylation and Attenuate Inflammation in Macrophages, 2020, The Journal of Immunology
  • FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors, 2023, Cancer Immunology Research
  • LPS induces GFAT2 expression to promote O-GlcNAcylation and attenuate inflammation in macrophages, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • FOXO1, un acteur de l'interaction hôte-pathogène dans le contexte de l'infection par le VIH-1, 2020, médecine/sciences

These publications suggest a focus on immunological pathways related to inflammation and cancer, as well as molecular interactions during viral infections. The research on CAR T cell therapy highlights involvement in advanced cancer immunotherapy strategies.

Frequent collaborators include:

  • Hasanain Al-Mukh
  • Léa Baudoin
  • Nabih Maraqa
  • Mostafa Khair
  • Patrick Pagésy

Bismuth's work appears in a range of scientific venues, with publications recorded in The Journal of Immunology, Cancer Immunology Research, bioRxiv (Cold Spring Harbor Laboratory), and médecine/sciences. This diversity reflects engagement with both peer-reviewed journals and preprint archives.

Best Publications

  • Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation

    Rémi Lasserre;Xiao-Jun Guo;Fabien Conchonaud;Fabien Conchonaud;Yannick Hamon;Yannick Hamon

  • ERM proteins regulate cytoskeleton relaxation promoting T cell-APC conjugation.

    Sophie Faure;Laura Inés Salazar-Fontana;Monique Semichon;Victor L J Tybulewicz

  • αEβ7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

    Audrey Le Floc'h;Abdelali Jalil;Isabelle Vergnon;Béatrice Le Maux Chansac

  • CD3/TCR Complex-Associated Lymphocyte Activation Gene-3 Molecules Inhibit CD3/TCR Signaling

    Sigrid Hannier;Muriel Tournier;Georges Bismuth;Frédéric Triebel

  • Fine tuning the immune response with PI3K

    David A. Fruman;Georges Bismuth

  • Human CD5 promotes B-cell survival through stimulation of autocrine IL-10 production.

    Hélène Gary-Gouy;Julie Harriague;Julie Harriague;Julie Harriague;Georges Bismuth;Georges Bismuth;Georges Bismuth;Cornelia Platzer;Cornelia Platzer;Cornelia Platzer

  • FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase.

    Stéphanie Fabre;Florent Carrette;Florent Carrette;Jing Chen;Valérie Lang

  • Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium

    E. Donnadieu;G. Bismuth;A. Trautmann

  • CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3–kinase– independent manner

    François Asperti-Boursin;François Asperti-Boursin;Eliana Real;Eliana Real;Georges Bismuth;Georges Bismuth;Alain Trautmann;Alain Trautmann

  • Imaging antigen-induced PI3K activation in T cells.

    Julie Harriague;Georges Bismuth

  • Immunological Synapses Are Versatile Structures Enabling Selective T Cell Polarization

    David Depoil;Rossana Zaru;Martine Guiraud;Anne Chauveau

  • Biological Activity of Soluble CD100. I. The Extracellular Region of CD100 Is Released from the Surface of T Lymphocytes by Regulated Proteolysis

    Abdellah Elhabazi;Stéphanie Delaire;Armand Bensussan;Laurence Boumsell

  • Calcium fluxes in T lymphocytes.

    E Donnadieu;G Bismuth;A Trautmann

  • Stable Activation of Phosphatidylinositol 3-Kinase in the T Cell Immunological Synapse Stimulates Akt Signaling to FoxO1 Nuclear Exclusion and Cell Growth Control

    Stéphanie Fabre;Valérie Lang;Julie Harriague;Aude Jobart

  • Ca2+ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca2+ stores. A study with the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin.

    Hélène Gouy;Daniel Cefai;Soren Brogger Christensen;Patrice Debré

  • ICOS Ligation Recruits the p50α PI3K Regulatory Subunit to the Immunological Synapse

    Camille Fos;Audrey Salles;Valérie Lang;Valérie Lang;Florent Carrette;Florent Carrette

  • Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1.

    Marine Leclerc;Elodie Voilin;Gwendoline Gros;Stéphanie Corgnac

  • CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization.

    Helga Schneider;Xin Smith;Hebin Liu;Georges Bismuth

  • Imaging early steps of human T cell activation by antigen-presenting cells.

    E Donnadieu;D Cefai;Y P Tan;G Paresys

  • Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation

    Alix Delaguillaumie;Julie Harriague;Sylvie Kohanna;Georges Bismuth

Frequent Co-Authors

Alain Trautmann
Alain Trautmann Institut Cochin
Patrice Debré
Patrice Debré Sorbonne University
Fathia Mami-Chouaib
Fathia Mami-Chouaib Institut Gustave Roussy
Salem Chouaib
Salem Chouaib Gulf Medical University
Alexandre Benmerah
Alexandre Benmerah Institut Imagine
Anne Caignard
Anne Caignard Grenoble Alpes University
Armand Bensussan
Armand Bensussan Hôpital Saint-Louis
Stefano Marullo
Stefano Marullo Université Paris Cité
Caroline Demangel
Caroline Demangel Institut Pasteur

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