World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
93
Citations
44449
World Ranking
948
National Ranking
2

Medicine

D-Index
93
Citations
44622
World Ranking
10685
National Ranking
2

Overview

Salem Chouaib is affiliated with Gulf Medical University in the United Arab Emirates. Their research is primarily situated at the intersection of medicine, biochemistry, genetics, molecular biology, immunology, and microbiology.

The main fields of study contributing to their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Within these domains, the scientist's subfields of focus are:

  • Oncology
  • Immunology
  • Cancer Research
  • Molecular Biology
  • Pulmonary and Respiratory Medicine

Key research topics covered in their publications include:

  • Cancer, Hypoxia, and Metabolism
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • RNA modifications and cancer
  • Cancer Cells and Metastasis
  • Immune Cell Function and Interaction
  • Epigenetics and DNA Methylation

The scientist has published multiple papers in notable scientific venues, with frequent contributions to:

  • Frontiers in Immunology
  • Cancers
  • Journal of Clinical Oncology
  • OncoImmunology
  • Cancer Research

Recent papers authored or coauthored by Salem Chouaib include:

  • "CD103+CD8+ TRM Cells Accumulate in Tumors of Anti-PD-1-Responder Lung Cancer Patients and Are Tumor-Reactive Lymphocytes Enriched with Tc17," 2020, Cell Reports Medicine
  • "Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies," 2021, Frontiers in Immunology
  • "Targeting HIF-1 alpha transcriptional activity drives cytotoxic immune effector cells into melanoma and improves combination immunotherapy," 2021, Oncogene
  • "Hypoxia-driven intratumor heterogeneity and immune evasion," 2020, Cancer Letters
  • "Integrating tumor hypoxic stress in novel and more adaptable strategies for cancer immunotherapy," 2020, Seminars in Cancer Biology

The scientist collaborates frequently with colleagues including:

  • Stéphane Terry
  • Raefa Abou Khouzam
  • Goutham Hassan Venkatesh
  • Stéphanie Buart
  • Husam Nawafleh

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

    Muhammad Zaeem Noman;Giacomo Desantis;Bassam Janji;Meriem Hasmim

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The host—tumor immune conflict: from immunosuppression to resistance and destruction

    Salem Chouaib;Carine Asselin-Paturel;Fathia Mami-Chouaib;Anne Caignard

  • New insights into the role of EMT in tumor immune escape

    Stéphane Terry;Pierre Savagner;Sandra Ortiz-Cuaran;Linda Mahjoubi

  • Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression.

    S Chouaib;K Welte;R Mertelsmann;B Dupont

  • Alteration of the Antitumor Immune Response by Cancer-Associated Fibroblasts.

    Linda Ziani;Salem Chouaib;Salem Chouaib;Jerome Thiery;Jerome Thiery

  • Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia.

    Muhammad Zaeem Noman;Meriem Hasmim;Yosra Messai;Stéphane Terry

  • Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer

    S Chouaib;S Chouaib;M Z Noman;M Z Noman;K Kosmatopoulos;M A Curran

  • Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell–Mediated Lysis

    Intissar Akalay;Bassam Janji;Meriem Hasmim;Muhammad Zaeem Noman

  • Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

    Joanna Baginska;Elodie Viry;Guy Berchem;Aurélie Poli

  • Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer.

    Guy Berchem;Muhammad Zaeem Noman;Manon Bosseler;Jerome Paggetti

  • Microglia-derived TGF-β as an important regulator of glioblastoma invasion—an inhibition of TGF-β-dependent effects by shRNA against human TGF-β type II receptor

    A Wesolowska;A Kwiatkowska;L Slomnicki;M Dembinski

  • αEβ7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

    Audrey Le Floc'h;Abdelali Jalil;Isabelle Vergnon;Béatrice Le Maux Chansac

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

    Muhammad Zaeem Noman;Bassam Janji;Bozena Kaminska;Kris Van Moer

  • Phosphostim-Activated γδ T Cells Kill Autologous Metastatic Renal Cell Carcinoma

    Emilie Viey;Gaëlle Fromont;Bernard Escudier;Yannis Morel

  • The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200

    Muhammad Zaeem Noman;Bassam Janji;Abderemane Abdou;Meriem Hasmim

  • The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes.

    Salem Chouaib;L. Chatenoud;D. Klatzmann;D. Fradelizi

  • Biology and clinical applications

    Salem Chouaib;Zohra Soua;Jean-Michel Mencia-Huerta;Armand Bensussan

Frequent Co-Authors

Fathia Mami-Chouaib
Fathia Mami-Chouaib Institut Gustave Roussy
Bassam Janji
Bassam Janji Luxembourg Institute of Health
Anne Caignard
Anne Caignard Grenoble Alpes University
Jean Paul Thiery
Jean Paul Thiery National University of Singapore
Bernard Escudier
Bernard Escudier Institut Gustave Roussy
Jean-Yves Blay
Jean-Yves Blay Claude Bernard University Lyon 1
Jean Bourhis
Jean Bourhis University of Lausanne
Caroline Robert
Caroline Robert University of Paris-Saclay
Laurence Albiges
Laurence Albiges Institut Gustave Roussy
Alexander M.M. Eggermont
Alexander M.M. Eggermont Institut Gustave Roussy

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