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Ursula Grohmann

Ursula Grohmann

D-Index & Metrics

Immunology

D-Index
70
Citations
21325
World Ranking
2392
National Ranking
94

Overview

Ursula Grohmann is affiliated with the University of Perugia in Italy. Their research focuses primarily on the intersections of neuroscience, medicine, and biochemistry, genetics, and molecular biology.

The main fields of study for this scientist include:

  • Neuroscience
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Grohmann's work spans several specific subfields, notably:

  • Biological Psychiatry
  • Immunology
  • Genetics
  • Behavioral Neuroscience
  • Psychiatry and Mental Health

Their research topics are diverse, with significant focus areas including:

  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Immune Cell Function and Interaction
  • Bipolar Disorder and Treatment
  • Immune cells in cancer
  • Inflammatory Bowel Disease
  • Eosinophilic Esophagitis

Recent papers authored or coauthored by Grohmann include:

  • Indoleamine 2,3-dioxygenase 1 (IDO1): an up-to-date overview of an eclectic immunoregulatory enzyme, 2021, FEBS Journal
  • Polyamines and Kynurenines at the Intersection of Immune Modulation, 2020, Trends in Immunology
  • Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma, 2020, Clinical Cancer Research
  • Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation, 2020, Proceedings of the National Academy of Sciences
  • 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine, 2021, Nature Communications

Frequent coauthors in Grohmann's publications are:

  • Giada Mondanelli (10 joint publications)
  • Maria Teresa Pallotta (7 joint publications)
  • Antonio Macchiarulo (7 joint publications)
  • Elisa Proietti (7 joint publications)
  • Ciriana Orabona (6 joint publications)

Contributing to their research, Grohmann has published repeatedly in key scientific venues such as:

  • Proceedings of the National Academy of Sciences
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • Inflammatory Bowel Diseases
  • FEBS Journal

Best Publications

  • Modulation of tryptophan catabolism by regulatory T cells.

    Francesca Fallarino;Ursula Grohmann;Kwang Woo Hwang;Ciriana Orabona

  • CTLA-4-Ig regulates tryptophan catabolism in vivo.

    Ursula Grohmann;Ciriana Orabona;Francesca Fallarino;Carmine Vacca

  • The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

    Francesca Fallarino;Ursula Grohmann;Sylvaine You;Barbara C. McGrath

  • T cell apoptosis by tryptophan catabolism.

    Francesca Fallarino;Ursula Grohmann;Carmine Vacca;Roberta Bianchi

  • Tolerance, DCs and tryptophan: much ado about IDO

    Ursula Grohmann;Francesca Fallarino;Paolo Puccetti

  • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

    Maria T Pallotta;Ciriana Orabona;Claudia Volpi;Carmine Vacca

  • Aryl hydrocarbon receptor control of a disease tolerance defence pathway

    Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino

  • Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

    Luigina Romani;Francesca Fallarino;Antonella De Luca;Claudia Montagnoli

  • IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation

    Paolo Puccetti;Ursula Grohmann

  • CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

    Ciriana Orabona;Ursula Grohmann;Maria Laura Belladonna;Francesca Fallarino

  • Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

    Ursula Grohmann;Claudia Volpi;Francesca Fallarino;Silvia Bozza

  • IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

    Ursula Grohmann;Maria Laura Belladonna;Roberta Bianchi;Ciriana Orabona

  • IL-23 and IL-12 Have Overlapping, but Distinct, Effects on Murine Dendritic Cells

    Maria Laura Belladonna;Jean-Christophe Renauld;Roberta Bianchi;Carmine Vacca

  • A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.

    Giada Mondanelli;Roberta Bianchi;Maria Teresa Pallotta;Ciriana Orabona

  • Control of immune response by amino acid metabolism.

    Ursula Grohmann;Vincenzo Bronte

  • Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

    Francesca Fallarino;Carmine Vacca;Ciriana Orabona;Maria L. Belladonna

  • Murine Plasmacytoid Dendritic Cells Initiate the Immunosuppressive Pathway of Tryptophan Catabolism in Response to CD200 Receptor Engagement

    Francesca Fallarino;Carine Asselin-Paturel;Carmine Vacca;Roberta Bianchi

  • A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice.

    Ursula Grohmann;Francesca Fallarino;Roberta Bianchi;Ciriana Orabona

  • Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis.

    Luigina Romani;Antonella Mencacci;Ursula Grohmann;S. Mocci

  • T Cell Apoptosis by Kynurenines

    Francesca Fallarino;Ursula Grohmann;Carmine Vacca;Ciriana Orabona

Frequent Co-Authors

Paolo Puccetti
Paolo Puccetti University of Perugia
Maria C. Fioretti
Maria C. Fioretti University of Perugia
Roberta Bianchi
Roberta Bianchi University of Perugia
Francesca Fallarino
Francesca Fallarino University of Perugia
Ciriana Orabona
Ciriana Orabona University of Perugia
Carmine Vacca
Carmine Vacca University of Perugia
Luigina Romani
Luigina Romani University of Perugia
Silvio Bicciato
Silvio Bicciato University of Modena and Reggio Emilia
Louis Boon
Louis Boon University of Amsterdam
Vincenzo Bronte
Vincenzo Bronte University of Verona

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